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Chemical Thiotepa

Name Thiotepa
CAS Type 1 Name Aziridine, 1,1',1''-phosphinothioylidynetris-
Equivalent Terms AI324916 | AI3 24916 | AI3-24916 | Girostan | NSC6396 | NSC 6396 | NSC-6396 | Tespa | Tespamin | Thiophosphamide | Thio Tepa | Thio-Tepa | Triethylenethiophosphoramide | Tris(1-aziridinyl)phosphine Sulfide
CAS Registry Number 52-24-4
Definition A very toxic alkylating antineoplastic agent also used as an insect sterilant. It causes skin, gastrointestinal, CNS, and bone marrow damage. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), thiotepa may reasonably be anticipated to be a carcinogen (Merck Index, 11th ed).
Structure Thiotepa
Curator Note For additional curated data about phosphorus, please also see Phosphorus and its chemical descendants.
Top Interacting
Genes
MeSH® ID D013852
External Links

Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Organophosphorus Compounds Has associated genes Has associated diseases Has associated exposure references Phosphoramides Has associated genes Has associated diseases Has associated exposure references Thiotepa Has associated genes Has associated diseases
2. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 1-Ring Has associated genes Has associated diseases Has associated exposure references Azirines Has associated genes Has associated diseases Aziridines Has associated genes Has associated diseases Triethylenephosphoramide Has associated genes Has associated diseases Thiotepa Has associated genes Has associated diseases

Top ↑ Descendants

Thiotepa Has associated genes Has associated diseases
  1-oxyl-2,2,6,6-tetramethyl-4-piperidyl-N,N,N',N'-bis(ethylene)phosphorodiamidothioate
  AVTMF protocol
  CTCb regimen Has associated diseases
  D-CECaT regimen
  MATILDE regimen
  MiCaT protocol
  MITT protocol
  MTV protocol
  MVT protocol
  STAMP V regimen
  TAVE protocol
  TAVH protocol
  TBV protocol
  thiotepa-glutathione conjugate
  TMF protocol Has associated diseases
  TMJ protocol
  TMM protocol
  T-NOP protocol
  TNT protocol
  TVTG protocol
  VTMFAP protocol
  VTMFP protocol
  VTMF protocol