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Chemical Toxins, Biological

These are exposure studies associated with the chemical and all of its children.

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  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Johnson NM, et al. (2010). Findings suggest that the incidence and level of aflatoxins and polycyclic aromatic hydrocarbon exposure was less than that observed in a high-risk population; however, participants consuming higher amounts of foods prone to aflatoxin contamination may be more vulnerable to exposure and interactions with other environmental/biological factors (i.e., hepatitis C virus). diet 1-hydroxypyrene | Aflatoxin M1 Study subjects United States urine 1-hydroxypyrene | Aflatoxin M1 Details
2. Lai H, et al. (2014). The findings of this study indicate that occupational aflatoxin B1 airway exposure might be associated with the risk of hepatocellular carcinoma among factory workers. Aflatoxin B1 Controls for disease:Carcinoma, Hepatocellular | Subjects with disease:Carcinoma, Hepatocellular | Workers China dust | serum aflatoxin-albumin adduct | Aflatoxin B1 Details Carcinoma, Hepatocellular
3. Groopman JD, et al. (2014). In this study we have found that aflatoxin exposure is ubiquitous among at least some of the rural populations of Nepal and Bangladesh, as assessed by a robust mass spectrometry-based albumin adduct biomarker. Aflatoxin B1 Children | Fetuses | Pregnant females Bangladesh|Nepal blood | blood, cord | serum aflatoxin B1-lysine adduct Details
4. Mitchell NJ, et al. (2017). Malnutrition and Enteric Disease Study (MAL-ED) Exposure to aflatoxin (a mycotoxin common in maize and groundnuts) has been associated with childhood stunting in sub-Saharan Africa; in an effort to further our understanding of growth impairment in relation to mycotoxins, biospecimens from a cohort of children in Bhaktapur (Nepal) were assessed for aflatoxin exposure at 15, 24, and 36 months of age. age Aflatoxins Children Nepal serum aflatoxin B1-lysine adduct Details
5. Mizrak D, et al. (2009). We have documented that in viral hepatitis patients, aflatoxin exposure is significantly higher than in healthy subjects in Turkey and it may play an important role in the development of hepatocellular carcinoma. diet | disease Aflatoxins Controls for disease:Hepatitis, Viral, Human | Subjects with disease:Hepatitis, Viral, Human Turkey serum Aflatoxin B1 | aflatoxin B2 | aflatoxin G1 | aflatoxin G2 Details
6. Jager AV, et al. (2014). We performed a longitudinal assessment to evaluate the short-term exposure to aflatoxins in Sao Paulo (Brazil) by determination of urine levels: aflatoxin M1 was found (but there was no significant difference among the mean levels in four sampling periods), and the levels indicate a low short-term exposure to aflatoxins through the diet. diet Aflatoxins Study subjects Brazil urine Aflatoxin M1 Details
7. Yard EE, et al. (2013). Kenya AIDS Indicator Survey (KAIS) Our findings suggest that aflatoxin exposure is a public health problem throughout Kenya, and it could be substantially impacting human health. Aflatoxins Pregnant females | Study subjects Kenya serum aflatoxin B1-lysine adduct Details
8. Liu Y, et al. (2010). Aflatoxin may play a causative role in 4.6-28.2% of all global hepatocellular carcinoma cases. Aflatoxins Study subjects Argentina|Australia|
Brazil|China|
Congo, the Democratic Republic of the|Egypt|
Ethiopia|Gambia|
India|Indonesia|
Iran, Islamic Republic of|Kenya|
Korea, Republic of|Malaysia|
Mexico|Mozambique|
Nigeria|Pakistan|
Philippines|South Africa|
Sudan|Tanzania, United Republic of|
Thailand|United States|
Zimbabwe
Aflatoxins Details Carcinoma, Hepatocellular
9. Shirima CP, et al. (2015). We investigated the association between child growth and aflatoxin and fumonisin exposure in Tanzania. Aflatoxins | fumonisin B1 Children Tanzania, United Republic of plasma | urine aflatoxin-albumin adduct | fumonisin B1 Details Growth Disorders
10. Liu L, et al. (2017). In an experimental situation, ambient coarse particulate matter (and its biological constituents of endotoxin and beta-1,3-D-glucan) may influence neural biomarker levels that reflect perturbations of blood-brain barrier integrity and systemic stress response in volunteers. beta-1,3-D-glucan | Endotoxins | Particulate Matter Study subjects Canada blood | urine Hydrocortisone | S100B | UCHL1 | Vanilmandelic Acid Details
11. Azziz-Baumgartner E, et al. (2012). Annual incidence of possible ciguatera fish poisoning was 4 per 1,000 person-years, and that of probable ciguatera fish poisoning was 7.5 per 1,000 person-years. Ciguatoxins Study subjects Puerto Rico Details Ciguatera Poisoning
12. Padhi BK, et al. (2017). Burning of household fuels could be a major source of endotoxin in homes; we measured endotoxin levels in different size fractions of particulate matter (PM10, PM2.5, and PM1) in homes using LPG (propane) vs. biomass fuel (complex mixtures), and estimated the deposition of particle-bound endotoxin in the respiratory tract. Complex Mixtures | Particulate Matter | Propane Study subjects India air, indoor | lung Carbon | Carbon Dioxide | Endotoxins | Particulate Matter Details Lung Diseases, Interstitial
13. Fessler MB, et al. (2017). Agricultural Lung Health Study (ALHS) | National Health and Nutrition Examination Survey (NHANES) We report an association between house dust endotoxin and leukocyte count in a national survey, and the finding was replicated in a farming population; peripheral leukocyte count may be influenced by residential endotoxin exposure in diverse settings. Dust | Endotoxins Study subjects | Subjects with gene influence:TLR4 United States dust, house | dust, indoor Endotoxins Details Leukocytosis | leukocyte differentiation | leukocyte homeostasis | lymphocyte differentiation | lymphocyte homeostasis | monocyte differentiation | monocyte homeostasis | neutrophil differentiation | neutrophil homeostasis
14. Stein MM, et al. (2016). The results of our studies in humans and mice indicate that the Amish environment provides protection against asthma by engaging and shaping the innate immune response. Dust | Endotoxins Children United States air Endotoxins Details Asthma | innate immune response
15. Mendy A, et al. (2018). National Health and Nutrition Examination Survey (NHANES) In a population-based sample of U.S. adults, endotoxin levels in homes were associated with a self-reported history of CBE diagnosis and chronic bronchitis symptoms, with stronger associations among people sensitized to inhalant allergens. Endotoxins Study subjects United States dust, house Endotoxins Details Bronchitis, Chronic | Emphysema
16. Wang Z, et al. (2012). We examined the difference in airborne bioaerosol levels in residential indoor environments measured using a robotic personal sampling surrogate (PIPER Mk IV) and a stationary sampler equipped with identical sampling equipment. PIPER, which is designed to simulate resuspension of the dust from flooring by young children, measured significantly higher endotoxin concentrations compared to the stationary sampler. Endotoxins Children United States air Endotoxins Details
17. Solomon GM, et al. (2006). We assessed potential human exposure to mold spores and endotoxin in New Orleans after the flooding of the city; unlike mold spores, the airborne endotoxin concentrations did not vary with flooded status or between indoor and outdoor environments. Endotoxins Study subjects United States air, indoor | air, outdoor Endotoxins Details
18. Semple S, et al. (2010). Airborne endotoxin concentrations in homes burning biomass fuels are orders of magnitude higher than those found in homes in developed countries where endotoxin exposure has been linked to respiratory illness in children. Endotoxins | Particulate Matter Malawi|Nepal Endotoxins | Particulate Matter Details
19. Lai PS, et al. (2016). Shanghai Textile Worker Study In this workplace-based cohort of occupational organic dust and smoking exposure, we find that occupational endotoxin exposure is associated with persistent increases in lung density, lung mass, and airway thickening even after exposure cessation. Endotoxins | Tobacco Smoke Pollution Workers China Details Lung Diseases | lung growth
20. de Rooij MMT, et al. (2018). The considerable spatial variation of ambient endotoxin concentrations measured in a livestock-dense area can largely be explained by land-use regression modeling based on livestock-related characteristics. Particulate Matter Netherlands air Endotoxins | Particulate Matter Details
1–20 of 20 results.