Skip navigation

Chemical Urea

1–50 of 2,281 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1,1,3,3-tetramethylurea positive regulation of natural killer cell mediated cytotoxicity 1,1,3,3-tetramethylurea results in decreased positive regulation of natural killer cell mediated cytotoxicity 1: Homo sapiens Killer Cells, Natural | Cells, Cultured   1
2. 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea cellular response to food Dietary Fats 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Dietary Fats results in increased cellular response to food] 1: Mus musculus Liver | Endoplasmic Reticulum   1
3. 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea cellular response to food Dietary Fats 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Dietary Fats results in increased cellular response to food] 1: Mus musculus Adipose Tissue | Endoplasmic Reticulum   1
4. 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea cell proliferation Diazepam | tetramethylenedisulfotetramine [Diazepam co-treated with 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea] promotes the reaction [tetramethylenedisulfotetramine results in increased cell proliferation] 1: Mus musculus Hippocampus | Astrocytes
2 genes: AKT1 | CYP1A1
1
5. 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea microglial cell activation Diazepam | tetramethylenedisulfotetramine [Diazepam co-treated with 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea] inhibits the reaction [tetramethylenedisulfotetramine results in increased microglial cell activation] 1: Mus musculus Hippocampus | Microglia   1
6. 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea positive regulation of monocyte extravasation AGT 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea inhibits the reaction [AGT protein modified form results in increased positive regulation of monocyte extravasation] 1: Mus musculus Aorta   1
7. 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea positive regulation of macrophage chemotaxis AGT 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea inhibits the reaction [AGT protein modified form results in increased positive regulation of macrophage chemotaxis] 1: Mus musculus Aorta   1
8. 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea positive regulation of T cell chemotaxis AGT 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea inhibits the reaction [AGT protein modified form results in increased positive regulation of T cell chemotaxis] 1: Mus musculus Aorta   1
9. 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea positive regulation of superoxide anion generation AGT 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea inhibits the reaction [AGT protein modified form results in increased positive regulation of superoxide anion generation] 1: Mus musculus Aorta
2 genes: AGT | CYBA
1
10. 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea positive regulation of NAD(P)H oxidase activity AGT | Superoxides 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea inhibits the reaction [[AGT protein modified form results in increased positive regulation of NAD(P)H oxidase activity] which results in increased chemical synthesis of Superoxides] 1: Mus musculus Aorta
2 genes: AGT | CYBA
1
11. 1-(2-chloroethyl)-1-nitrosourea cell death 1-(2-chloroethyl)-1-nitrosourea results in increased cell death     1
12. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea DNA repair 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased DNA repair 1: Homo sapiens MCF-7 Cells
9 genes: ATM | CHEK1 | CHEK2 | ERCC3 | ERCC5 | FANCD2 | MGMT | PARP1 | RAD51
1
13. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea mitotic cell cycle arrest 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased mitotic cell cycle arrest 1: Homo sapiens MCF-7 Cells   1
14. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea apoptotic process 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased apoptotic process 1: Homo sapiens MCF-7 Cells
8 genes: ATM | CASP7 | CASP8 | CASP9 | CHEK1 | CHEK2 | ERCC3 | PARP1
1
15. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea cell proliferation 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in decreased cell proliferation 1: Homo sapiens MCF-7 Cells   1
16. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea cell proliferation 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in decreased cell proliferation] 1: Homo sapiens MCF-7 Cells   1
17. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea cell proliferation 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in decreased cell proliferation] 1: Homo sapiens MCF-7 Cells   1
18. 1,3-dimethylthiourea apoptotic process Puromycin Aminonucleoside 1,3-dimethylthiourea inhibits the reaction [Puromycin Aminonucleoside results in increased apoptotic process] 1: Rattus norvegicus Kidney Glomerulus | Epithelial Cells | Cells, Cultured
19 genes: BAX | BCL2 | BCL2L2 | CASP3 | CASP8 | CASP9 | FAS | FASLG | HMOX1 | IL1B | MAPK3 | NFKB1 | POLB | PRKCA | RAF1 | TNF | TNFRSF1A | TP53 | TRP53
1
19. 1,3-dimethylthiourea positive regulation of Fas signaling pathway lead acetate 1,3-dimethylthiourea inhibits the reaction [lead acetate results in increased positive regulation of Fas signaling pathway] 1: Mus musculus Erythrocytes   1
20. 1,3-dimethylthiourea protein transport into plasma membrane raft lead acetate 1,3-dimethylthiourea inhibits the reaction [lead acetate results in increased protein transport into plasma membrane raft] 1: Mus musculus Erythrocytes   1
21. 1,3-dimethylthiourea apoptotic process Cadmium 1,3-dimethylthiourea inhibits the reaction [Cadmium results in increased apoptotic process] 1: Longpotamon honanense Gills
19 genes: BAX | BCL2 | BCL2L2 | CASP3 | CASP8 | CASP9 | FAS | FASLG | HMOX1 | IL1B | MAPK3 | NFKB1 | POLB | PRKCA | RAF1 | TNF | TNFRSF1A | TP53 | TRP53
1
22. 1,3-dimethylthiourea DNA damage response, detection of DNA damage Cadmium 1,3-dimethylthiourea inhibits the reaction [Cadmium results in increased DNA damage response, detection of DNA damage] 1: Longpotamon honanense Gills   1
23. 1,3-dimethylthiourea hydrogen peroxide biosynthetic process Cadmium 1,3-dimethylthiourea inhibits the reaction [Cadmium results in increased hydrogen peroxide biosynthetic process] 1: Longpotamon honanense Gills   1
24. 1,3-dimethylthiourea regulation of cell size Manganese 1,3-dimethylthiourea inhibits the reaction [Manganese affects regulation of cell size] 1: Rattus norvegicus Astrocytes | Cells, Cultured   1
25. 1,3-dimethylthiourea apoptotic process Asbestos, Amosite 1,3-dimethylthiourea inhibits the reaction [Asbestos, Amosite results in increased apoptotic process] 1: Homo sapiens Lung | Cell Line, Tumor
19 genes: BAX | BCL2 | BCL2L2 | CASP3 | CASP8 | CASP9 | FAS | FASLG | HMOX1 | IL1B | MAPK3 | NFKB1 | POLB | PRKCA | RAF1 | TNF | TNFRSF1A | TP53 | TRP53
1
26. 1,3-dimethylthiourea apoptotic process Hydrogen Peroxide 1,3-dimethylthiourea inhibits the reaction [Hydrogen Peroxide results in increased apoptotic process] 1: Homo sapiens Lung | Cell Line, Tumor
19 genes: BAX | BCL2 | BCL2L2 | CASP3 | CASP8 | CASP9 | FAS | FASLG | HMOX1 | IL1B | MAPK3 | NFKB1 | POLB | PRKCA | RAF1 | TNF | TNFRSF1A | TP53 | TRP53
1
27. 1,3-dimethylurea membrane lipid catabolic process Anthracyclines 1,3-dimethylurea inhibits the reaction [Anthracyclines results in increased membrane lipid catabolic process] 1: Mus musculus Heart | Microsomes   1
28. 1,3-dimethylurea membrane lipid catabolic process Anthracyclines 1,3-dimethylurea inhibits the reaction [Anthracyclines results in increased membrane lipid catabolic process] 1: Mus musculus Liver | Microsomes   1
29. 1-(4-chlorophenyl)-3-(3-(4-chlorophenyl)-5,5-dimethyl-1-(3-(5-nitrofuran-2-yl)allyldienehydrazinocarbonylmethyl)-2-oxoimidazolidin-4-yl)-1-hydroxyurea protein ubiquitination 1-(4-chlorophenyl)-3-(3-(4-chlorophenyl)-5,5-dimethyl-1-(3-(5-nitrofuran-2-yl)allyldienehydrazinocarbonylmethyl)-2-oxoimidazolidin-4-yl)-1-hydroxyurea results in decreased protein ubiquitination   1 gene: VCP 1
30. 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea positive regulation of cytosolic calcium ion concentration N-(1-azabicyclo(2.2.2)oct-3-yl)(5-(2-pyridyl)thiophene-2-carboxamide) [N-(1-azabicyclo(2.2.2)oct-3-yl)(5-(2-pyridyl)thiophene-2-carboxamide) co-treated with 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea] results in increased positive regulation of cytosolic calcium ion concentration 1: Homo sapiens Induced Pluripotent Stem Cells | Neurons | Cells, Cultured 1 gene: JAK2 1
31. 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea positive regulation of cytosolic calcium ion concentration epibatidine [epibatidine co-treated with 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea] results in increased positive regulation of cytosolic calcium ion concentration 1: Homo sapiens Induced Pluripotent Stem Cells | Neurons | Cells, Cultured 1 gene: JAK2 1
32. 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea positive regulation of cytosolic calcium ion concentration Choline [Choline co-treated with 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea] results in increased positive regulation of cytosolic calcium ion concentration 1: Homo sapiens Induced Pluripotent Stem Cells | Neurons | Cells, Cultured 1 gene: JAK2 1
33. 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea positive regulation of sodium ion transmembrane transport Acetylcholine [Acetylcholine co-treated with 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea] results in increased positive regulation of sodium ion transmembrane transport 1: Homo sapiens Induced Pluripotent Stem Cells | Neurons | Cells, Cultured   1
34. 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea positive regulation of potassium ion transmembrane transport Acetylcholine [Acetylcholine co-treated with 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea] results in increased positive regulation of potassium ion transmembrane transport 1: Homo sapiens Induced Pluripotent Stem Cells | Neurons | Cells, Cultured   1
35. 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea positive regulation of cytosolic calcium ion concentration methyllycaconitine | N-(1-azabicyclo(2.2.2)oct-3-yl)(5-(2-pyridyl)thiophene-2-carboxamide) methyllycaconitine inhibits the reaction [[N-(1-azabicyclo(2.2.2)oct-3-yl)(5-(2-pyridyl)thiophene-2-carboxamide) co-treated with 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea] results in increased positive regulation of cytosolic calcium ion concentration] 1: Homo sapiens Induced Pluripotent Stem Cells | Neurons | Cells, Cultured 1 gene: JAK2 1
36. 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea negative regulation of acetylcholine-gated cation channel activity Nicotine 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea inhibits the reaction [Nicotine results in increased negative regulation of acetylcholine-gated cation channel activity] 1: Homo sapiens CHO Cells   1
37. 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea negative regulation of acetylcholine-gated cation channel activity CHRNA7 | Nicotine 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea inhibits the reaction [[Nicotine results in increased negative regulation of acetylcholine-gated cation channel activity] which results in decreased activity of CHRNA7 protein] 1: Homo sapiens CHO Cells   1
38. 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea negative regulation of acetylcholine-gated cation channel activity Acetylcholine 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea inhibits the reaction [Acetylcholine results in increased negative regulation of acetylcholine-gated cation channel activity] 1: Homo sapiens CHO Cells   1
39. 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea negative regulation of acetylcholine-gated cation channel activity Acetylcholine | CHRNA7 1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea inhibits the reaction [[Acetylcholine results in increased negative regulation of acetylcholine-gated cation channel activity] which results in decreased activity of CHRNA7 protein] 1: Homo sapiens CHO Cells   1
40. 1-(6-((2-(dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo(3,4-b)pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea monocyte chemotaxis CCL2 1-(6-((2-(dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo(3,4-b)pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea inhibits the reaction [CCL2 protein results in increased monocyte chemotaxis] 1: Homo sapiens Monocytes | Cell Line, Tumor   1
41. 1-(6-((2-(dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo(3,4-b)pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea chemotaxis CCL4 1-(6-((2-(dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo(3,4-b)pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea affects the reaction [CCL4 protein results in increased chemotaxis] 1: Homo sapiens Blood | Leukocytes, Mononuclear   1
42. 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea response to endoplasmic reticulum stress Carbon Tetrachloride 1-trifluoromethoxyphenyl-3-(1-propionylpiperidine-4-yl)urea inhibits the reaction [Carbon Tetrachloride results in increased response to endoplasmic reticulum stress] 1: Mus musculus Liver
8 genes: ATF4 | DDIT3 | EIF2AK3 | EIF2S1 | ERN1 | HSPA5 | THBS1 | XBP1
1
43. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate apoptotic process Ouabain 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Ouabain results in increased apoptotic process] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured
3 genes: IL1B | MAPK1 | MAPK3
1
44. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate cell death Digoxin 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Digoxin results in increased cell death] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured   1
45. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate sodium ion import across plasma membrane Scorpion Venoms 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Scorpion Venoms results in increased sodium ion import across plasma membrane] 1: Rattus norvegicus Cerebellum | Neurons | Cells, Cultured 1 gene: SLC8A1 1
46. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate sodium ion import across plasma membrane Dizocilpine Maleate | Scorpion Venoms 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate promotes the reaction [Dizocilpine Maleate inhibits the reaction [Scorpion Venoms results in increased sodium ion import across plasma membrane]] 1: Rattus norvegicus Cerebellum | Neurons | Cells, Cultured 1 gene: SLC8A1 1
47. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate sodium ion import across plasma membrane Dizocilpine Maleate | Nifedipine | Scorpion Venoms Nifedipine promotes the reaction [2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate promotes the reaction [Dizocilpine Maleate inhibits the reaction [Scorpion Venoms results in increased sodium ion import across plasma membrane]]] 1: Rattus norvegicus Cerebellum | Neurons | Cells, Cultured 1 gene: SLC8A1 1
48. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate cell death Scorpion Venoms 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [Scorpion Venoms results in increased cell death] 1: Rattus norvegicus Cerebellum | Neurons | Cells, Cultured   1
49. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate cell death Dizocilpine Maleate | Scorpion Venoms [Dizocilpine Maleate co-treated with 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate] inhibits the reaction [Scorpion Venoms results in increased cell death] 1: Rattus norvegicus Cerebellum | Neurons | Cells, Cultured   1
50. 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate cell death Dizocilpine Maleate | Nifedipine | Scorpion Venoms [Dizocilpine Maleate co-treated with 2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate co-treated with Nifedipine] inhibits the reaction [Scorpion Venoms results in increased cell death] 1: Rattus norvegicus Cerebellum | Neurons | Cells, Cultured   1
1–50 of 2,281 results.