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Chemical Vinca Alkaloids

Name Vinca Alkaloids
Equivalent Term Alkaloids, Vinca
Definition A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.
Top Interacting
Genes
MeSH® ID D014748
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Top ↑ Ancestors

1. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Alkaloids Has associated genes Has associated diseases Has associated exposure references Indole Alkaloids Has associated genes Has associated diseases Has associated exposure references Secologanin Tryptamine Alkaloids Has associated genes Has associated diseases Vinca Alkaloids Has associated genes Has associated diseases
2. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, Fused-Ring Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated exposure references Indoles Has associated genes Has associated diseases Has associated exposure references Indole Alkaloids Has associated genes Has associated diseases Has associated exposure references Secologanin Tryptamine Alkaloids Has associated genes Has associated diseases Vinca Alkaloids Has associated genes Has associated diseases

Top ↑ Descendants

Vinca Alkaloids Has associated genes Has associated diseases
  11-methyl-20,21-dinoreburnamenine
  16a'-homo-leurosidine
  21'-oxoleurosine
  2'-hydroxyethyl apovincaminate
  2-(nitrooxy)ethyl apovincaminate
  6-hydroxyvinburnine
  AF 698
  apovincaminic acid
  catharanthine
  catharanthinol
  conophylline
  dihydrodinoreburnameninol
  eburnamonine Has associated genes Has associated diseases
  EC 0489
  EC140 compound
  EC145 Has associated diseases
  ent-4-desacetoxy-6,7-dihydrovindorosine
  ethyl 21,21,21-trifluoroapovincaminate
  formyl-leurosine Has associated diseases
  herbadine
  hunterioside
  leurosidine N'b-oxide
  leurosine
  leurosine methiodide
  LHT 2 - 02
  majdine
  methoxymethyl apovincaminate
  piracetam, vinpocetine drug combination
  pleurosine
  quebrachidine
  RGH 4417
  roseadine
  rutovincine
  S 12363
  strictosamide
  strictosidine
  VA 033
View node Vinblastine Has associated genes Has associated diseases
View node Vincamine Has associated genes Has associated diseases
  vincarubine
  vinconate
  vincorine
View node Vincristine Has associated genes Has associated diseases
View node Vindesine Has associated genes Has associated diseases
  vindolicine
  vinpocetine Has associated genes Has associated diseases
  vinzolidine