These are exposure studies associated with the chemical and all of its children.
|Reference||Associated Study Title||Author's Summary||Study Factors||Stressor||Receptors||Country||Medium||Exposure Marker||Measurements||Outcome|
|1.||Wesselink AK, et al. (2016).||Pregnancy Study Online (PRESTO)||Total caffeine intake among males, but not females, was associated with fecundability, although the association was not monotonic; with respect to individual beverages, caffeinated black tea was associated with slight reductions among females, and caffeinated soda and energy drink were associated with reduced fecundability among males.||diet | sex||Caffeine||Study subjects||Canada|United States||beverage, caffeinated | tea, black||Caffeine||Details||female pregnancy|
|2.||Go YM, et al. (2015).||We examined quantification strategies to enhance the usefulness of high-resolution metabolomics data for cumulative exposome research; the results provide a simple reference standardization protocol in which individual chemical concentrations are estimated by comparison to a concurrently analyzed, pooled reference sample with known chemical concentrations.||Caffeine | Chlorobenzoates | chlorsulfuron | Cotinine | Fyrol PCF | hippuric acid | meobal | octylphenol | pirimicarb | Styrene||Study subjects||United States||plasma||Caffeine | Chlorobenzoates | chlorsulfuron | Cotinine | Fyrol PCF | hippuric acid | meobal | octylphenol | pirimicarb | Styrene||Details|
|3.||Yang H, et al. (2015).||Male Reproductive Health in Chongqing College students (MARHCS)||The primary objectives of the MARHCS study are to investigate the associations of male reproductive health in young adults with sociopsychobehavioral factors, as well as changes of environmental exposure due to the relocation from rural campus (in University Town) to metro-campus (in central downtown).||diet | tobacco||Caffeine | Tobacco Smoke Pollution||Study subjects||China||semen||Details||spermatogenesis | sperm motility|
|4.||Kataria A, et al. (2015).||National Health and Nutrition Examination Survey (NHANES)||Perfluoroalkyl acids are associated with a reduction in kidney function and increased uric acid levels in otherwise healthy adolescents.||Fluorocarbons||Children||United States||serum||perfluorooctane sulfonic acid | perfluorooctanoic acid | Uric Acid||Details||glomerular filtration|
|5.||Kasperczyk S, et al. (2014).||We examined the effects of N-acetylcysteine administration on the non-enzymatic defense systems (e.g., uric acid, albumin, bilirubin and alpha-tocopherol) in male workers exposed to lead, over a 12 week study period.||Lead||Workers||Poland||blood||ALB | alpha-Tocopherol | Bilirubin | Lead | Lipid Peroxides | Uric Acid | zinc protoporphyrin||Details|
|6.||Schreinemachers DM, et al. (2015).||National Health and Nutrition Examination Survey (NHANES)||This study investigated associations between urinary perchlorate and biomarkers of oxidative stress and iron homeostasis, including blood urea nitrogen, lymphocyte counts, serum uric acid, serum iron, and red blood cell counts.||perchlorate||Study subjects||United States||serum | urine||Iron | perchlorate | Uric Acid||Details||erythrocyte homeostasis | iron ion homeostasis | lymphocyte homeostasis|