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Chemical 17-Ketosteroids

1–50 of 106 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 16-hydroxyandrost-4-en-3,17-dione steroid biosynthetic process Colforsin [Colforsin results in increased steroid biosynthetic process] which results in increased secretion of 16-hydroxyandrost-4-en-3,17-dione 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
2. 17-dihydroequilenin lipoprotein oxidation 17-dihydroequilenin results in decreased lipoprotein oxidation 1: Homo sapiens Plasma   1
3. 19-hydroxy-4-androstene-3,17-dione steroid biosynthetic process Colforsin [Colforsin results in increased steroid biosynthetic process] which results in increased secretion of 19-hydroxy-4-androstene-3,17-dione analog 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
4. 2-methoxyestrone estrogen catabolic process Plant Extracts [Plant Extracts results in increased estrogen catabolic process] which results in increased chemical synthesis of 2-methoxyestrone 1: Homo sapiens MCF-7 Cells   1
5. 2-methoxyestrone estrogen catabolic process biochanin A [biochanin A results in increased estrogen catabolic process] which results in increased chemical synthesis of 2-methoxyestrone 1: Homo sapiens MCF-7 Cells   1
6. 2-methoxyestrone estrogen metabolic process Plant Extracts [Plant Extracts results in decreased estrogen metabolic process] which results in decreased chemical synthesis of 2-methoxyestrone 1: Homo sapiens Mammary Glands, Human | Epithelial Cells | Cell Line   1
7. 2-methoxyestrone estrogen catabolic process formononetin [formononetin results in increased estrogen catabolic process] which results in increased chemical synthesis of 2-methoxyestrone 1: Homo sapiens MCF-7 Cells   1
8. 2-methoxyestrone estrogen metabolic process isoliquiritigenin [isoliquiritigenin results in increased estrogen metabolic process] which results in increased chemical synthesis of 2-methoxyestrone 1: Homo sapiens Mammary Glands, Human | Epithelial Cells | Cell Line   1
9. 2-methoxyestrone estrogen metabolic process licochalcone A [licochalcone A results in decreased estrogen metabolic process] which results in decreased chemical synthesis of 2-methoxyestrone 1: Homo sapiens Mammary Glands, Human | Epithelial Cells | Cell Line   1
10. 4-hydroxyestrone estrogen metabolic process isoliquiritigenin [isoliquiritigenin results in increased estrogen metabolic process] which results in increased chemical synthesis of 4-hydroxyestrone metabolite 1: Homo sapiens Mammary Glands, Human | Epithelial Cells | Cell Line
3 genes: CYP1B1 | UGT1A1 | UGT2B11
1
11. 4-hydroxyestrone estrogen metabolic process Plant Extracts [Plant Extracts results in decreased estrogen metabolic process] which results in decreased chemical synthesis of 4-hydroxyestrone metabolite 1: Homo sapiens Mammary Glands, Human | Epithelial Cells | Cell Line
3 genes: CYP1B1 | UGT1A1 | UGT2B11
1
12. 4-hydroxyestrone DNA damage response, detection of DNA damage NFE2L2 NFE2L2 gene mutant form promotes the reaction [4-hydroxyestrone results in increased DNA damage response, detection of DNA damage] 1: Homo sapiens Breast | Epithelial Cells | Cell Line   1
13. 4-hydroxyestrone DNA damage response, detection of DNA damage LINC-ROR LINC-ROR mRNA promotes the reaction [4-hydroxyestrone results in increased DNA damage response, detection of DNA damage] 1: Homo sapiens Breast | Epithelial Cells | Cell Line   1
14. 4-hydroxyestrone DNA modification LINC-ROR | shikonin shikonin inhibits the reaction [LINC-ROR mRNA promotes the reaction [4-hydroxyestrone results in increased DNA modification]] 1: Homo sapiens Breast | Epithelial Cells | Cell Line 1 gene: CYP1B1 1
15. 4-hydroxyestrone DNA modification NFE2L2 NFE2L2 gene mutant form promotes the reaction [4-hydroxyestrone results in increased DNA modification] 1: Homo sapiens Breast | Epithelial Cells | Cell Line 1 gene: CYP1B1 1
16. 4-hydroxyestrone DNA damage response, detection of DNA damage LINC-ROR | shikonin shikonin inhibits the reaction [LINC-ROR mRNA promotes the reaction [4-hydroxyestrone results in increased DNA damage response, detection of DNA damage]] 1: Homo sapiens Breast | Epithelial Cells | Cell Line   1
17. 4-hydroxyestrone estrogen metabolic process licochalcone A [licochalcone A results in decreased estrogen metabolic process] which results in decreased chemical synthesis of 4-hydroxyestrone metabolite 1: Homo sapiens Mammary Glands, Human | Epithelial Cells | Cell Line
3 genes: CYP1B1 | UGT1A1 | UGT2B11
1
18. 4-hydroxyestrone DNA modification 4-hydroxyestrone results in increased DNA modification 1: Homo sapiens Breast | Epithelial Cells | Cell Line 1 gene: CYP1B1 1
19. 4-hydroxyestrone DNA modification LINC-ROR LINC-ROR mRNA promotes the reaction [4-hydroxyestrone results in increased DNA modification] 1: Homo sapiens Breast | Epithelial Cells | Cell Line 1 gene: CYP1B1 1
20. 4-hydroxyestrone estrogen metabolic process Plant Extracts [Plant Extracts results in increased estrogen metabolic process] which results in increased chemical synthesis of 4-hydroxyestrone metabolite 1: Homo sapiens Mammary Glands, Human | Epithelial Cells | Cell Line
3 genes: CYP1B1 | UGT1A1 | UGT2B11
1
21. 4-hydroxyestrone DNA damage response, detection of DNA damage 4-hydroxyestrone results in increased DNA damage response, detection of DNA damage 1: Homo sapiens Breast | Epithelial Cells | Cell Line   1
22. 4-hydroxyestrone-4-methyl ether estrogen catabolic process Plant Extracts [Plant Extracts results in increased estrogen catabolic process] which results in increased chemical synthesis of 4-hydroxyestrone-4-methyl ether 1: Homo sapiens MCF-7 Cells   1
23. 4-hydroxyestrone-4-methyl ether estrogen catabolic process biochanin A [biochanin A results in increased estrogen catabolic process] which results in increased chemical synthesis of 4-hydroxyestrone-4-methyl ether 1: Homo sapiens MCF-7 Cells   1
24. 4-hydroxyestrone-4-methyl ether estrogen catabolic process daidzein [daidzein results in increased estrogen catabolic process] which results in increased chemical synthesis of 4-hydroxyestrone-4-methyl ether 1: Homo sapiens MCF-7 Cells   1
25. 4-hydroxyestrone-4-methyl ether DNA modification 4-hydroxyestrone-4-methyl ether results in increased DNA modification MCF-7 Cells 1 gene: CYP1B1 1
26. 4-hydroxyestrone-4-methyl ether estrogen catabolic process Genistein [Genistein results in increased estrogen catabolic process] which results in increased chemical synthesis of 4-hydroxyestrone-4-methyl ether 1: Homo sapiens MCF-7 Cells   1
27. 4-hydroxyestrone-4-methyl ether estrogen catabolic process formononetin [formononetin results in increased estrogen catabolic process] which results in increased chemical synthesis of 4-hydroxyestrone-4-methyl ether 1: Homo sapiens MCF-7 Cells   1
28. androstane-3,17-dione lipid biosynthetic process androstane-3,17-dione results in increased lipid biosynthetic process 1: Cricetinae Ear | Sebaceous Glands   1
29. Androstenedione androgen biosynthetic process di-n-hexyl phthalate [di-n-hexyl phthalate results in decreased androgen biosynthetic process] which results in decreased abundance of Androstenedione 1: Rattus norvegicus Testis
4 genes: CYP17A1 | HSD17B2 | HSD17B3 | HSD3B1
1
30. Androstenedione cell proliferation Androstenedione results in increased cell proliferation 1: Homo sapiens Breast | Cell Line, Tumor
4 genes: AR | CREBBP | IGF1 | TNF
1
31. Androstenedione cell proliferation Estradiol Androstenedione inhibits the reaction [Estradiol results in increased cell proliferation] 1: Homo sapiens MCF-7 Cells
4 genes: AR | CREBBP | IGF1 | TNF
1
32. Androstenedione negative regulation of steroid hormone biosynthetic process Venlafaxine Hydrochloride [Venlafaxine Hydrochloride results in increased negative regulation of steroid hormone biosynthetic process] which results in decreased abundance of Androstenedione 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
33. Androstenedione androgen metabolic process bicalutamide | Dutasteride | Goserelin | Ketoconazole [[Goserelin co-treated with Dutasteride co-treated with bicalutamide co-treated with Ketoconazole] affects androgen metabolic process] which results in increased abundance of Androstenedione 1: Homo sapiens Prostate
3 genes: CYP19A1 | CYP3A4 | HSD17B1
1
34. Androstenedione androgen metabolic process bicalutamide | Dutasteride | Goserelin [[Goserelin co-treated with Dutasteride co-treated with bicalutamide] affects androgen metabolic process] which results in increased abundance of Androstenedione 1: Homo sapiens Prostate
3 genes: CYP19A1 | CYP3A4 | HSD17B1
1
35. Androstenedione steroid biosynthetic process Colforsin [Colforsin results in increased steroid biosynthetic process] which results in increased secretion of Androstenedione 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
12 genes: CYP11A1 | CYP11B1 | CYP11B2 | CYP17A1 | CYP19A1 | HSD17B1 | HSD17B12 | HSD17B2 | HSD17B3 | HSD3B1 | NR0B1 | STAR
1
36. Androstenedione C21-steroid hormone metabolic process Fluconazole [Fluconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of Androstenedione 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
2 genes: CYP19A1 | HSD3B1
1
37. Androstenedione negative regulation of steroid hormone biosynthetic process Tramadol [Tramadol results in increased negative regulation of steroid hormone biosynthetic process] which results in decreased abundance of Androstenedione 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
38. Androstenedione C21-steroid hormone metabolic process Fluconazole [Fluconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of Androstenedione 1: Homo sapiens Adrenal Cortex | Cell Line
2 genes: CYP19A1 | HSD3B1
1
39. Androstenedione C21-steroid hormone metabolic process Ketoconazole [Ketoconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of Androstenedione 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
2 genes: CYP19A1 | HSD3B1
1
40. Androstenedione C21-steroid hormone metabolic process Ketoconazole [Ketoconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of Androstenedione 1: Homo sapiens Adrenal Cortex | Cell Line
2 genes: CYP19A1 | HSD3B1
1
41. Androstenedione lipid biosynthetic process Androstenedione results in increased lipid biosynthetic process 1: Cricetinae Ear | Sebaceous Glands 1 gene: INS 1
42. Androstenedione androgen metabolic process Equol [Equol affects androgen metabolic process] which results in decreased abundance of Androstenedione 1: Mus musculus Ovarian Follicle
3 genes: CYP19A1 | CYP3A4 | HSD17B1
1
43. Androstenedione testosterone secretion Androstenedione results in increased testosterone secretion 1: Rattus norvegicus Leydig Cells | Cells, Cultured   1
44. Androstenedione negative regulation of steroid hormone biosynthetic process Duloxetine Hydrochloride [Duloxetine Hydrochloride results in increased negative regulation of steroid hormone biosynthetic process] which results in decreased abundance of Androstenedione 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
45. Androsterone androgen metabolic process bicalutamide | Dutasteride | Goserelin | Ketoconazole [[Goserelin co-treated with Dutasteride co-treated with bicalutamide co-treated with Ketoconazole] affects androgen metabolic process] which results in decreased abundance of Androsterone 1: Homo sapiens Serum 1 gene: UGT2B7 1
46. Androsterone androgen metabolic process bicalutamide | Dutasteride | Goserelin [[Goserelin co-treated with Dutasteride co-treated with bicalutamide] affects androgen metabolic process] which results in decreased abundance of Androsterone 1: Homo sapiens Serum 1 gene: UGT2B7 1
47. Dehydroepiandrosterone C21-steroid hormone metabolic process Ketoconazole [Ketoconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of Dehydroepiandrosterone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
2 genes: CYP19A1 | HSD3B1
1
48. Dehydroepiandrosterone androgen metabolic process bicalutamide | Dutasteride | Goserelin | Ketoconazole [[Goserelin co-treated with Dutasteride co-treated with bicalutamide co-treated with Ketoconazole] affects androgen metabolic process] which results in decreased abundance of Dehydroepiandrosterone 1: Homo sapiens Serum
8 genes: CYP19A1 | CYP3A4 | ESR1 | HSD17B1 | HSD17B4 | NR3C1 | PPARGC1A | SRD5A1
1
49. Dehydroepiandrosterone detection of temperature stimulus involved in sensory perception of pain Dehydroepiandrosterone results in decreased detection of temperature stimulus involved in sensory perception of pain 1: Rattus norvegicus Lower Extremity 1 gene: TLR4 1
50. Dehydroepiandrosterone cell proliferation 4-chlorobiphenyl Dehydroepiandrosterone promotes the reaction [4-chlorobiphenyl metabolite results in decreased cell proliferation] 1: Homo sapiens Keratinocytes | Cell Line
14 genes: AKT1 | AR | BAD | BAX | BCL2 | BCL2L1 | CYP1A1 | EGFR | EPO | GH1 | PRL | SRC | TNF | TP53
1
1–50 of 106 results.