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Chemical Dideoxynucleosides

Name Dideoxynucleosides
Equivalent Terms 2',3' Dideoxynucleosides | 2',3'-Dideoxynucleosides | ddNus | Dideoxyribonucleosides
Definition Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
Top Interacting
Genes
MeSH® ID D015224
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Top ↑ Ancestors

ChemicalsNucleic Acids, Nucleotides, and Nucleosides Has associated genes Has associated diseases Has associated exposure references Nucleosides Has associated genes Has associated diseases Has associated exposure references Deoxyribonucleosides Has associated genes Has associated diseases Has associated exposure references Dideoxynucleosides Has associated genes Has associated diseases

Top ↑ Descendants

Dideoxynucleosides Has associated genes Has associated diseases
  1-(2',3'-dideoxy-3'(hydroxymethyl)erythropentofuranosyl)cytosine
  1,2-dipalmitoylphosphatidyldideoxyguanosine
  1-(2-fluoro-4-iodo-2,4-dideoxyxylopyranosyl)-2-nitroimidazole
  2',3'-deoxy-D-apio-D-furanoadenosine
  2',3'-didehydro-2',3'-dideoxyuridine
  2',3'-dideoxy-2',3'-didehydroguanine nucleoside
  2',3'-dideoxy-3'-aminoadenosine
  2',3'-dideoxy-3'-fluoro-2-thiothymidine
  2',3'-dideoxy-3'-O-methylthymidine
  2',3'-dideoxy-6-iodoguanosine
  2',3'-dideoxycarbocyclic thymidine
  2',3'-dideoxyformycin A
  2',3'-dideoxyguanosine
  2',3'-dideoxy-N(6)-cyclohexyladenosine
  2',3'-dideoxythymidine
  2',3'-dideoxyuridine
  2',5'-dichloro-2',5'-dideoxyuridine
  2,6-diaminopurine 2',3'-didehydro-2',3'-dideoxyriboside
  2'-chloro-2',3'-dideoxyuridinene
  2'-fluoro-2',3'-dideoxyguanosine
  2'-methylcarbovir
  3'-(3-(2-chloroethyl)-3-nitrosourea)-3'-deoxythymidine
  3'-(3-(2-chloroethyl)-3-nitrosoureido)-2',3'-dideoxy-5-fluorouridine
  3' (3-(2-chloroethyl)-3-nitrosoureido)-2',3'-dideoxyuridine
  3',3'-difluoro-3'-deoxythymidine
  3',5'-dideoxythymidine
  3'-acetamido-2',3'-dideoxythymidine
  3'-amino-2',3'-dideoxyuridine
  3'amino-3'-deoxy-5'-glucopyranuronosylthymidine
  3'-aminothymidine
  3'-azido-2',3'-dideoxyguanosine
  3'-C-methylidene-2',3'-dideoxy-5-methyluridine
  3'-deoxy-2',3'-didehydro-2'fluorothymidine
  3'-deoxy-3'-iodothymidine
  3'-fluoro-2',3'-dideoxy-5-bromouridine
  3'-fluoro-2',3'-dideoxy-5-iodouridine
  3'-fluoro-2',3'-dideoxyguanosine Has associated diseases
  3'-fluoro-2',3'-dideoxyuridine
  3'-isocyano-2',3'-dideoxyuridine
  3'-methylamino-2',3'-dideoxyribosylthymine
  3'-thio-3'-deoxythymidine
  5'-amino-2',5'-dideoxyguanosine
  5'-amino-5'-deoxythymidine
  5-bromo-2',3'-dideoxyuridine
  5-bromo-6-methoxy-5,6-dihydro-3'-fluoro-3'-deoxythymidine
  5'-deoxy-5'fluorothymidine
  5-fluoro-2',3'-dideoxy-3'-fluorouridine
  5-iodo-2',3'-dideoxyuridine
  5-iodo-6-methoxy-5,6-dihydro-3'-fluoro-3'-deoxythymidine
  5'-isocyano-2',5'-dideoxyuridine
  5'-isocyano-5'-deoxythymidine
  5-o-carboranyl-2',3'-didehydro-2',3'-dideoxyuridine
  6-aminocarbovir
  6-chloro-2',3'-dideoxyguanosine
  6-chloro-2',3'-dideoxyinosine
  6-thioguanine-alpha-2,3-dideoxy-3-(hydroxymethyl)-D-erythro-pentafuranose
  9-(c-4,t-5-bis(hydroxymethyl)cyclopent-2-en-r-1-yl)-9H-adenine
  abacavir Has associated genes Has associated diseases
  abacavir, lamivudine drug combination Has associated diseases
  alovudine Has associated diseases
  carbocyclic 3'-oxa-2',3'-dideoxy-7-deazaguanosine
  carbocyclic 3'-oxa-2',3'-dideoxyguanosine
  carbovir
  carbovir-5'-O-glucuronide
View node Stavudine Has associated genes Has associated diseases
View node Zalcitabine Has associated genes Has associated diseases
View node Dideoxyadenosine Has associated genes Has associated diseases
View node Didanosine Has associated genes Has associated diseases
  Kivexa
  N-(5'-adenosyl)-N'-(5'-thymidyl)azelaamide
  N,N'-dideoxythymidine-3,4,9,10-perylene-tetracarboxylic acid diimide
  norabacavir
  norcarbovir
  raluridine
View node Zidovudine Has associated genes Has associated diseases