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Chemical Neprilysin

Name Neprilysin
Equivalent Terms Antigen, CD10 | Antigens, CD10 | Antigens, Leukemia, Common Acute Lymphoblastic | Atriopeptidase | CALLA Antigen | Carboxypeptidase, Enkephalin Dipeptidyl | CD10 Antigen | CD10 Antigens | Common Acute Lymphoblastic Leukemia Antigens | Dipeptidyl Carboxypeptidase, Enkephalin | Endopeptidase 24.11 | Endopeptidase-24.11 | Endopeptidase 24.11, Neutral | Endopeptidase, Neutral | Enkephalinase | Enkephalinase 24.11 | Enkephalinase-24.11 | Enkephalin Dipeptidyl Carboxypeptidase | Enzyme, YGG-Forming | Kidney Brush Border Neutral Proteinase | Kidney-Brush-Border Neutral Proteinase | Membrane Metallo Endopeptidase | Membrane Metallo-Endopeptidase | Metallo-Endopeptidase, Membrane | Metalloendopeptidase, Thermolysin-Like | Neutral Endopeptidase | Neutral Endopeptidase 24.11 | Neutral Proteinase, Kidney-Brush-Border | Thermolysin Like Metalloendopeptidase | Thermolysin-Like Metalloendopeptidase | YGG Forming Enzyme | YGG-Forming Enzyme
Definition Enzyme that is a major constituent of kidney brush-border membranes and is also present to a lesser degree in the brain and other tissues. It preferentially catalyzes cleavage at the amino group of hydrophobic residues of the B-chain of insulin as well as opioid peptides and other biologically active peptides. The enzyme is inhibited primarily by EDTA, phosphoramidon, and thiorphan and is reactivated by zinc. Neprilysin is identical to common acute lymphoblastic leukemia antigen (CALLA Antigen), an important marker in the diagnosis of human acute lymphocytic leukemia. There is no relationship with CALLA PLANT.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D015260
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1. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Antigens Has associated genes Has associated diseases Has associated exposure references Antigens, Neoplasm Has associated genes Has associated diseases Neprilysin
2. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Antigens Has associated genes Has associated diseases Has associated exposure references Antigens, Surface Has associated genes Has associated diseases Antigens, Differentiation Has associated genes Has associated diseases Antigens, CD Has associated genes Has associated diseases Neprilysin
3. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Biomarkers Has associated genes Has associated diseases Antigens, Differentiation Has associated genes Has associated diseases Antigens, CD Has associated genes Has associated diseases Neprilysin
4. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Biomarkers Has associated genes Has associated diseases Biomarkers, Tumor Has associated genes Has associated diseases Neprilysin

Top ↑ Descendants

Neprilysin
  endopeptidase 24.11, Bombyx
  KB220Z
  MMEL1 protein, human
  NEP-2 protein, C elegans
  neprilysin 2, Drosophila
  neprilysin 2, mouse
  neprilysin 2, rat