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Chemical Leukotrienes

Name Leukotrienes
Definition A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.
Top Interacting
Genes
MeSH® ID D015289
External Links

Top ↑ Ancestors

1. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Unsaturated Has associated genes Has associated diseases Has associated exposure references Eicosanoids Has associated genes Has associated diseases Has associated exposure references Arachidonic Acids Has associated genes Has associated diseases Has associated exposure references Leukotrienes Has associated genes Has associated diseases Has associated exposure references
2. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Unsaturated Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Essential Has associated genes Has associated diseases Has associated exposure references Arachidonic Acids Has associated genes Has associated diseases Has associated exposure references Leukotrienes Has associated genes Has associated diseases Has associated exposure references
3. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Inflammation Mediators Has associated genes Has associated diseases Has associated exposure references Autacoids Has associated genes Has associated diseases Has associated exposure references Eicosanoids Has associated genes Has associated diseases Has associated exposure references Leukotrienes Has associated genes Has associated diseases Has associated exposure references

Top ↑ Descendants

Leukotrienes Has associated genes Has associated diseases Has associated exposure references
  12-HPETE Has associated genes Has associated diseases
  14,15-dihydroperoxyeicosatetraenoic acid
  15-hydroperoxy-5,8,11,13-eicosatetraenoic acid Has associated genes Has associated diseases
  15-hydroperoxy-5,9,11,13-eicosatetraenoic acid
  5,15-dihydroperoxyeicosatetraenoic acid
  5-hydroxy-6-(2-keto-3-thiopropionyl)-7,9,11,14-eicosatetraenoic acid
  8,15-diHPETE
  8-hydroperoxyeicosatetraenoic acid
  arachidonic acid 5-hydroperoxide
  cysteinyl-leukotriene Has associated genes Has associated diseases
  eoxin C4
View node Leukotriene B4 Has associated genes Has associated diseases Has associated exposure references
  leukotriene E5
View node Leukotriene A4 Has associated genes Has associated diseases
View node SRS-A Has associated genes Has associated diseases