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Chemical Nimustine

Name Nimustine
CAS Type 1 Name Urea, N'-((4-amino-2-methyl-5-pyrimidinyl)methyl)-N-(2-chloroethyl)-N-nitroso-
Equivalent Terms ACNU | NSC 245382
CAS Registry Number 42471-28-3
Definition Antineoplastic agent especially effective against malignant brain tumors. The resistance which brain tumor cells acquire to the initial effectiveness of this drug can be partially overcome by the simultaneous use of membrane-modifying agents such as reserpine, calcium antagonists such as nicardipine or verapamil, or the calmodulin inhibitor, trifluoperazine. The drug has also been used in combination with other antineoplastic agents or with radiotherapy for the treatment of various neoplasms.
Structure Nimustine
Top Interacting
Genes
MeSH® ID D015376
External Links

Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Nitroso Compounds Has associated genes Has associated diseases Has associated exposure references Nitrosourea Compounds Has associated genes Has associated diseases Nimustine Has associated genes Has associated diseases
2. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Urea Has associated genes Has associated diseases Has associated exposure references Nitrosourea Compounds Has associated genes Has associated diseases Nimustine Has associated genes Has associated diseases

Top ↑ Descendants

Nimustine Has associated genes Has associated diseases
  AAABC protocol
  AAAP protocol
  AVN protocol
  CE-AVN protocol
  COMP-VAN protocol
  DAV protocol Has associated diseases
  PAV protocol