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Chemical Cilastatin

Name Cilastatin
CAS Type 1 Name 2-Heptenoic acid, 7-((2-amino-2-carboxyethyl)thio)-2-(((2,2-dimethylcyclopropyl)carbonyl)amino)-, (R-(R*,S*-(Z)))-
Equivalent Terms 0791, MK | Cilastatin Monosodium Salt | Cilastatin Sodium | MK0791 | MK 0791 | MK791 | MK 791 | MK-791 | Monosodium Salt, Cilastatin | Salt, Cilastatin Monosodium | Sodium, Cilastatin
CAS Registry Number 82009-34-5
Definition A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.
Structure Cilastatin
Top Interacting
Genes
MeSH® ID D015377
External Links

Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Hydrocarbons Has associated genes Has associated diseases Has associated exposure references Hydrocarbons, Cyclic Has associated genes Has associated diseases Has associated exposure references Hydrocarbons, Alicyclic Has associated genes Has associated diseases Has associated exposure references Cycloparaffins Has associated genes Has associated diseases Has associated exposure references Cyclopropanes Has associated genes Has associated diseases Cilastatin Has associated genes Has associated diseases
2. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Unsaturated Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Monounsaturated Has associated genes Has associated diseases Has associated exposure references Cilastatin Has associated genes Has associated diseases

Top ↑ Descendants

Cilastatin Has associated genes Has associated diseases
  cilastatin, imipenem drug combination Has associated diseases
  N-acetylcilastatin