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Chemical Histocompatibility Antigens Class I

Name Histocompatibility Antigens Class I
Equivalent Terms Antigens, Class I | Class I Antigens | Class I Histocompatibility Antigens | Class I Human Antigens | Class I Major Histocompatibility Antigens | Human Class I Antigens | I Antigens, Class
Definition Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D015395
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Top ↑ Ancestors

1. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Antigens Has associated genes Has associated diseases Has associated exposure references Antigens, Surface Has associated diseases Histocompatibility Antigens Histocompatibility Antigens Class I
2. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Antigens Has associated genes Has associated diseases Has associated exposure references Isoantigens Histocompatibility Antigens Histocompatibility Antigens Class I

Top ↑ Descendants

Histocompatibility Antigens Class I
  C31 protein, mouse
  D(kappa) (62-85) peptide
  Fc receptor, neonatal
  feline leukocyte antigen
  Gogo-H
  H2-M3 antigen
View node H-2 Antigens
  HCG8 protein, human
View node Hemochromatosis Protein
  histocompatibility antigen 37
  histocompatibility antigen DLA
  Histocompatibility Antigen H-2D
  histocompatibility antigen H-8
  histocompatibility antigen T10b
  histocompatibility antigen T10c
  histocomptibility antigen H-42
View node HLA-A Antigens
  HLA-AR antigen
View node HLA-B Antigens
View node HLA-C Antigens
  HLA-E antigen
  HLA-F antigens
View node HLA-G Antigens
  HLA-hc protein, human
  LA45 antigen
  M10.5 protein, mouse
  Mamu-A 01 antigen
  Mamu-A 02 antigen
  Mamu-B 01 antigen, Macaca mulatta
  Mamu-I antigen
  Mamu-Mhc-BJ antigen
  MHC class I-related chain A
  MHC Ib Qa-2 antigen
  MICB antigen
  MR1 protein, human
  Mr1 protein, mouse
  Mr1 protein, rat
  PD7 antigen, Sus scrofa
  pregnancy-specific antigen, sheep
  Q surface antigens
  RAET1E protein, human
  T22 antigen
  Tla antigens
  UL16 binding protein 1, mouse
  ZNRD1AS gene product, human