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Chemical Cytochalasin D

Name Cytochalasin D
CAS Type 1 Name (11)Cytochalasa-6(12),13,19-triene-1,17-dione, 21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,18R,19E,21R)-
CAS Registry Number 22144-77-0
Definition A fungal metabolite that blocks cytoplasmic cleavage by blocking formation of contractile microfilament structures resulting in multinucleated cell formation, reversible inhibition of cell movement, and the induction of cellular extrusion. Additional reported effects include the inhibition of actin polymerization, DNA synthesis, sperm motility, glucose transport, thyroid secretion, and growth hormone release.
Structure Cytochalasin D
Top Interacting
Genes
MeSH® ID D015638
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ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Toxins, Biological Has associated genes Has associated diseases Has associated exposure references Mycotoxins Has associated genes Has associated diseases Has associated exposure references Cytochalasins Has associated genes Has associated diseases Cytochalasin D Has associated genes Has associated diseases

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None.