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Chemical Pentostatin

Name Pentostatin
CAS Type 1 Name Imidazo(4,5-d)(1,3)diazepin-8-ol, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (R)-
Equivalent Terms 2' Deoxycoformycin | 2'-Deoxycoformycin | CI825 | CI 825 | CI-825 | Co-Vidarabine | Deoxycoformycin | Nipent | NSC218321 | NSC 218321 | NSC-218321
CAS Registry Number 53910-25-1
Definition A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Structure Pentostatin
Top Interacting
Genes
MeSH® ID D015649
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Top ↑ Ancestors

1. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 1-Ring Has associated genes Has associated diseases Has associated exposure references Pyrimidines Has associated genes Has associated diseases Has associated exposure references Pyrimidine Nucleosides Has associated genes Has associated diseases Formycins Has associated genes Has associated diseases Coformycin Has associated genes Has associated diseases Pentostatin Has associated genes Has associated diseases
2. ChemicalsNucleic Acids, Nucleotides, and Nucleosides Has associated genes Has associated diseases Has associated exposure references Nucleosides Has associated genes Has associated diseases Has associated exposure references Deoxyribonucleosides Has associated genes Has associated diseases Has associated exposure references Pentostatin Has associated genes Has associated diseases
3. ChemicalsNucleic Acids, Nucleotides, and Nucleosides Has associated genes Has associated diseases Has associated exposure references Nucleosides Has associated genes Has associated diseases Has associated exposure references Pyrimidine Nucleosides Has associated genes Has associated diseases Formycins Has associated genes Has associated diseases Coformycin Has associated genes Has associated diseases Pentostatin Has associated genes Has associated diseases

Top ↑ Descendants

Pentostatin Has associated genes Has associated diseases
  2'-deoxycoformycin 5'-phosphate
  8-ketodeoxycoformycin
  adechlorin
  carbapentostain