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Chemical 1-Methyl-4-phenylpyridinium

Name 1-Methyl-4-phenylpyridinium
CAS Type 1 Name Pyridinium, 1-methyl-4-phenyl-
Equivalent Terms 1 Methyl 4 phenylpyridine | 1-Methyl-4-phenylpyridine | 1 Methyl 4 phenylpyridinium | 1 Methyl 4 phenylpyridinium Chloride | 1-Methyl-4-phenylpyridinium Chloride | 1 Methyl 4 phenylpyridinium Ion | 1-Methyl-4-phenylpyridinium Ion | Cyperquat | N Methyl 4 phenylpyridine | N-Methyl-4-phenylpyridine | N-Methyl-4-phenylpyridinium
CAS Registry Number 48134-75-4
Definition An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.
Structure 1-Methyl-4-phenylpyridinium
Top Interacting
Genes
MeSH® ID D015655
External Links

Top ↑ Ancestors

ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 1-Ring Has associated genes Has associated diseases Has associated exposure references Pyridines Has associated genes Has associated diseases Has associated exposure references Pyridinium Compounds Has associated genes Has associated diseases Has associated exposure references 1-Methyl-4-phenylpyridinium Has associated genes Has associated diseases

Top ↑ Descendants

1-Methyl-4-phenylpyridinium Has associated genes Has associated diseases
  1-methyl-4-(2-methylphenyl)pyridinium
  1-methyl-4-(4'-acetamidophenyl)pyridinium
  1-methyl-4-cyclohexylpyridinium