These are exposure studies associated with the chemical and all of its children.
|Reference||Associated Study Title||Author's Summary||Study Factors||Stressor||Receptors||Country||Medium||Exposure Marker||Measurements||Outcome|
|1.||Huang YF, et al. (2017).||Our results support a role for exposure to 4-nonylphenol and bisphenol A and possibly inflammation in increasing oxidative/nitrative stress and decreasing antioxidant activity during pregnancy.||4-nonylphenol | bisphenol A||Pregnant females||Taiwan, Province of China||blood | blood, cord | urine||4-nonylphenol | 8-epi-prostaglandin F2alpha | 8-nitroguanine | 8-oxo-7-hydrodeoxyguanosine | bisphenol A | GPX1 | TNF||Details||negative regulation of glutathione peroxidase activity | tumor necrosis factor production|
|2.||Ferguson KK, et al. (2016).||In the present mediation analysis we statistically demonstrate within a causal framework that the relationship between phthalate exposure and spontaneous preterm birth is mediated in part by phthalate-induced oxidative stress, which has not been elucidated clearly in human or animal studies previously.||8-epi-prostaglandin F2alpha | Diethylhexyl Phthalate | monobutyl phthalate||Pregnant females||United States||urine||Details||Premature Birth | detection of oxidative stress|
|3.||Lundström SL, et al. (2011).||Several of the altered oxylipins have known or suspected bronchoprotective or anti-inflammatory effects, suggesting a possible reduced anti-inflammatory response in asthmatics following exposure to subway air.||disease||Air Pollutants||Controls for disease:Asthma | Subjects with disease:Asthma||Sweden||lung||12,13-epoxy-9- keto-10-octadecenoic acid
||Details||negative regulation of inflammatory response | oxylipin biosynthetic process|
|4.||Chen C, et al. (2007).||Long-term exposure to Ozone is associated with elevated 8-isoprostane (8-iso-PGF), which suggests that 8-iso-PGF is a good biomarker of oxidative damage related to air pollution.||Nitrogen Dioxide | Ozone | Particulate Matter||Study subjects||United States||air | blood||8-isoprostaglandin F1alpha | Nitrogen Dioxide | Ozone | Particulate Matter||Details|