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Chemical Factor VIIIa

Name Factor VIIIa
CAS Type 1 Name Blood-coagulation factor VIIIa, procoagulant
Equivalent Terms Activated Factor VIII | Blood Coagulation Factor VIII, Activated | Coagulation Factor VIIIa | Factor 8A | Factor Eight A | Factor VIIIa, Coagulation | Factor VIII, Activated | Factor VIIIa Heavy Chain, 200 kDa Isoform | Factor VIIIa Heavy Chain, 92 kDa Isoform | Factor VIIIa Light Chain | Factor VIII, Thrombin Activated | Factor VIII, Thrombin-Activated | Thrombin-Activated Factor VIII
CAS Registry Number 72175-66-7
Definition Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similar in structure and generation to factor Va.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D015944
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Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Blood Coagulation Factors Has associated genes Has associated diseases Has associated exposure references Factor VIII Factor VIIIa

Top ↑ Descendants

None.