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Chemical Granulocyte Colony-Stimulating Factor

Name Granulocyte Colony-Stimulating Factor
CAS Type 1 Name Colony-stimulating factor, granulocyte
Equivalent Term G-CSF
CAS Registry Number 143011-72-7
Definition A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines.
Curation Status No gene interactions have been curated for this chemical yet.
MeSH® ID D016179
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Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Cytokines Has associated genes Has associated diseases Hematopoietic Cell Growth Factors Has associated genes Has associated diseases Colony-Stimulating Factors Has associated genes Has associated diseases Granulocyte Colony-Stimulating Factor Has associated diseases

Top ↑ Descendants

Granulocyte Colony-Stimulating Factor Has associated diseases
  balugrastim
  CAG protocol
  CLAG protocol
  EVAC-G-CSF protocol
View node Filgrastim Has associated diseases
  FLAG protocol Has associated diseases
  FLANG protocol
  FSK0808
  granulocyte colony-stimulating factor, Tyr(1)-Tyr(3)-
  hematopoietic lineage cell-specific protein 1, mouse
  HM10460A
  Ida-FLAG protocol Has associated diseases
  lenograstim
  leridistim
  MAD protocol
  Maxy G34
  myelopoietin
  nartograstim
  OLFM4 protein, human
  pegylated granulocyte colony-stimulating factor
  pegylated granulocyte colony-stimulating factor, human
  SD-01 recombinant
  THP-COPBLM regimen