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Chemical Fibroblast Growth Factor 2

Name Fibroblast Growth Factor 2
Equivalent Terms Basic Fibroblast Growth Factor | Cartilage Derived Growth Factor | Cartilage-Derived Growth Factor | Class II Heparin-Binding Growth Factor | FGF2 | FGF 2 | FGF-2 | Fibroblast Growth Factor-2 | Fibroblast Growth Factor, Basic | HBGF-2 | Heparin-Binding Growth Factor Class II | Prostate Epithelial Cell Growth Factor | Prostatropin
CAS Registry Number 103107-01-3
Definition A single-chain polypeptide growth factor that plays a significant role in the process of WOUND HEALING and is a potent inducer of PHYSIOLOGIC ANGIOGENESIS. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D016222
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Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Fibroblast Growth Factors Fibroblast Growth Factor 2

Top ↑ Descendants

Fibroblast Growth Factor 2
  basic fibroblast growth factor-saporin mitotoxin, recombinant
  FGF-P peptide
  hexafin2 peptide
  KCB-1 protein, recombinant