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Chemical Aphidicolin

Name Aphidicolin
CAS Type 1 Name 9,15-Cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol, 3,17-dihydroxy-4-methyl-, (3alpha,4alpha,5alpha,17alpha)-
Equivalent Terms Aphidicolin, (3-S-(3alpha,4beta,4abeta,6aalpha,8alpha,9alpha,11aalpha,11balpha))-Isomer | ICI69653 | ICI 69653 | ICI-69653 | NSC234714 | NSC 234714 | NSC-234714 | NSC351140 | NSC 351140 | NSC-351140
CAS Registry Number 38966-21-1
Definition An antiviral antibiotic produced by Cephalosporium aphidicola and other fungi. It inhibits the growth of eukaryotic cells and certain animal viruses by selectively inhibiting the cellular replication of DNA polymerase II or the viral-induced DNA polymerases. The drug may be useful for controlling excessive cell proliferation in patients with cancer, psoriasis or other dermatitis with little or no adverse effect upon non-multiplying cells.
Structure Aphidicolin
Top Interacting
Genes
MeSH® ID D016590
External Links

Top ↑ Ancestors

ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Hydrocarbons Has associated genes Has associated diseases Has associated exposure references Terpenes Has associated genes Has associated diseases Has associated exposure references Diterpenes Has associated genes Has associated diseases Aphidicolin Has associated genes Has associated diseases

Top ↑ Descendants

Aphidicolin Has associated genes Has associated diseases
  18-nor-3-ketoaphidicolin
  3,16-diketoaphidicolan
  3-ketoaphidicolin
  aphidicolin-17-monoacetate
  aphidicolin glycinate Has associated genes Has associated diseases
  inflatin A
  inflatin B
  inflatin G