Skip navigation

Chemical Trimetrexate

Name Trimetrexate
CAS Type 1 Name 2,4-Quinazolinediamine, 5-methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)-
Equivalent Terms CI898 | CI 898 | CI-898 | Hydrate, Trimetrexate | Ipsen Brand of Trimetrexate | JB11 | JB 11 | JB-11 | Monohydrate, Monoacetate Trimetrexate | NSC249008 | NSC 249008 | NSC-249008 | NSC328564 | NSC 328564 | NSC-328564 | Trimetrexate Hydrate | Trimetrexate Ipsen Brand | Trimetrexate Monohydrate, Monoacetate
CAS Registry Number 52128-35-5
Definition A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
Structure Trimetrexate
Top Interacting
Genes
MeSH® ID D016597
External Links

Top ↑ Ancestors

ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, Fused-Ring Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated exposure references Quinazolines Has associated genes Has associated diseases Trimetrexate Has associated genes Has associated diseases

Top ↑ Descendants

Trimetrexate Has associated genes Has associated diseases
  trimetrexate glucuronate