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Chemical Leukotriene A4

Name Leukotriene A4
Equivalent Terms Leukotriene A | Leukotriene A 4 | Leukotriene A-4 | Leukotrienes A | LTA4
Definition (2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-HPETE via the stereospecific removal of a proton at C-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., LEUKOTRIENE B4 and cysteinyl-leukotrienes. Alternatively, leukotriene A4 is converted into LEUKOTRIENE C4 by glutathione-S-transferase or into 5,6-di-HETE by the epoxide-hydrolase. (From Dictionary of Prostaglandins and Related Compounds, 1990)
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Genes
MeSH® ID D017572
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1. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Unsaturated Has associated genes Has associated diseases Has associated exposure references Eicosanoids Has associated genes Has associated diseases Has associated exposure references Arachidonic Acids Has associated genes Has associated diseases Has associated exposure references Leukotrienes Has associated genes Has associated diseases Has associated exposure references Leukotriene A4 Has associated genes Has associated diseases
2. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Unsaturated Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Essential Has associated genes Has associated diseases Has associated exposure references Arachidonic Acids Has associated genes Has associated diseases Has associated exposure references Leukotrienes Has associated genes Has associated diseases Has associated exposure references Leukotriene A4 Has associated genes Has associated diseases
3. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Inflammation Mediators Has associated genes Has associated diseases Has associated exposure references Autacoids Has associated genes Has associated diseases Has associated exposure references Eicosanoids Has associated genes Has associated diseases Has associated exposure references Leukotrienes Has associated genes Has associated diseases Has associated exposure references Leukotriene A4 Has associated genes Has associated diseases

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Leukotriene A4 Has associated genes Has associated diseases
  11,12-leukotriene A4
  14,15-dehydroleukotriene A4
  14,15-leukotriene A4
  19-((2-azido-5-iodo)benzoyloxy)leukotriene A(4)
  19-((2-azido-5-trimethylstannyl)benzoyloxy)leukotriene A(4)
  5,6-methanoleukotriene A4
  leukotriene A methyl ester Has associated genes Has associated diseases