Skip navigation

Chemical B7-1 Antigen

Name B7-1 Antigen
Equivalent Terms Antigen, B7 1 | Antigen, B7-1 | Antigens, CD80 | B7 1 Antigen | B7 1 Costimulatory Molecule | B7-1 Costimulatory Molecule | B7 1 Ligand | B7-1 Ligand | B Cell Activation Antigen | B-Cell Activation Antigen | CD80 Antigen | CD80 Antigens | Costimulatory Molecule, B7-1 | Ligand, B7-1
Definition A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D018122
External Links

Top ↑ Ancestors

1. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Antigens Has associated genes Has associated diseases Has associated exposure references Antigens, Surface Has associated diseases B7 Antigens B7-1 Antigen
2. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases B7 Antigens B7-1 Antigen

Top ↑ Descendants

None.