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Chemical Dopamine Antagonists

Name Dopamine Antagonists
Equivalent Terms Antagonists, Dopamine | Antagonists, Dopamine Receptor | Antagonists, Dopaminergic | Blockers, Dopamine | Dopamine Blockers | Dopamine Receptor Antagonists | Dopaminergic Antagonists | Receptor Antagonists, Dopamine
Definition Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME.
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Genes
MeSH® ID D018492
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1. ChemicalsChemical Actions and Uses Has associated genes Has associated diseases Has associated exposure references Pharmacologic Actions Has associated genes Has associated diseases Has associated exposure references Molecular Mechanisms of Pharmacological Action Has associated genes Has associated diseases Has associated exposure references Neurotransmitter Agents Has associated genes Has associated diseases Has associated exposure references Dopamine Agents Has associated genes Has associated diseases Dopamine Antagonists Has associated genes Has associated diseases
2. ChemicalsChemical Actions and Uses Has associated genes Has associated diseases Has associated exposure references Pharmacologic Actions Has associated genes Has associated diseases Has associated exposure references Physiological Effects of Drugs Has associated genes Has associated diseases Has associated exposure references Neurotransmitter Agents Has associated genes Has associated diseases Has associated exposure references Dopamine Agents Has associated genes Has associated diseases Dopamine Antagonists Has associated genes Has associated diseases

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Dopamine Antagonists Has associated genes Has associated diseases
  Dopamine D2 Receptor Antagonists