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Chemical Macrolides

Name Macrolides
Definition A group of often glycosylated macrocyclic compounds formed by chain extension of multiple PROPIONATES cyclized into a large (typically 12, 14, or 16)-membered lactone. Macrolides belong to the POLYKETIDES class of natural products, and many members exhibit ANTIBIOTIC properties.
Top Interacting
Genes
MeSH® ID D018942
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Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Lactones Has associated genes Has associated diseases Has associated exposure references Macrolides Has associated genes Has associated diseases Has associated exposure references
2. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Lactones Has associated genes Has associated diseases Has associated exposure references Polyketides Has associated genes Has associated diseases Has associated exposure references Macrolides Has associated genes Has associated diseases Has associated exposure references
3. ChemicalsPolycyclic Compounds Has associated genes Has associated diseases Has associated exposure references Macrocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Polyketides Has associated genes Has associated diseases Has associated exposure references Macrolides Has associated genes Has associated diseases Has associated exposure references

Top ↑ Descendants

Macrolides Has associated genes Has associated diseases Has associated exposure references
  10,11-dihydrodictyostatin
  10-aza-10-demethyl-9-deoxo-11-deoxyerythromycin A
  10-deoxymethynolide
  10-desmethyllasonolide A
  10-oxahexadecanolide
  11,11'-O-dimethyl-14'-deethyl-14'-methylelaiophylin
  11',12'-dehydroelaiophylin
  11-oxahexadecanolide
  12-hydroxy-4-methyldecahydro-1H-benzo(d)oxecine-2,9-dione
  12-oxahexadecanolide
  13,29-dihydroxymilbemycin A4
  13-demethyllyngbyaloside B
  13-deoxytedanolide
  13H-dibenzo(d,h)(1,3,7)oxadiazecine-8,14-dione
  14-ethyl-2,5,11-trimethyl-4,13,19,20-tetraoxa-tricyclo(14.2.1.1(7,10))eicosane-3,12-dione
  15G256iota
  16-hydroxyverrucarin A
  16-normethyldictyostatin
  16-O-desmethyl-17-desmethoxyrapamycin
  18-deoxynargenicin A1
  20,22-didehydro-19,21-didehydroxy-21-demaleoyl-24-demethylbafilomycin C1
  20-(5-(2-imidazolinyl)-2-benzimidazolyl)tylosin
  20-(5-(imidazolinyl)-2-benzimidazolyl)desmycosin
  20-(5-(N-isopropylamidino)-2-benzimidazolyl)desmycosin
  20-(5-(N-isopropylamidino)-2-benzimidazolyl)tylosin
  20-(5-(N-morpholinylamidino)-2-benzimidazolyl)tylosin
  20-(N-(3-(dimethylamino)propyl)-N-alanylamino)-20-deoxorepromicin
  21-demaleoyl-19-O-methyl-24-demethylbafilomycin C1
  22-epoxyberkeleydione
  2,3-didehydro-5-O-mycaminosyl-23-O-acetyltylonolide
  2',4',23-tri-O-acetyl-5-O-mycaminosyltylonolide-20-diethylketal
  2',4',4''-Tri-O-acetyl-2,3-anhydrodesmycosin
  2',4', 4''-Tri-O-acetyldesmycosin-20-diethylketal
  24-demethylbafilomycin C
  26-fluoroepothilone B
  27-hydroxymilbemycin A3
  27-hydroxymilbemycin A4
  27-oxomilbemycin A3
  27-oxomilbemycin A4
  29-deoxymaklamicin
  2'-desmethoxy spinosyn D
  2-hydroxy-24-oxooctacosanolide
  2-hydroxytetracosanolide
  2R-(n-butyl)-16-methyl-3S,5S,7S,9R,11R,13R,15S,26S, 27R-nonahydroxyoctacosa-16,18,20,22,24-pentaenoic acid, 27-lactone
  2S-sanctolide A
  30-hydroxymycalolide A
  32-hydroxymycalolide A
  38-hydroxymycalolide A
  3'-demethyldeoxymethymycin
  3'-demethylmethymycin
  3'-desmethoxy spinosyn D
  3-hydroxy-11-methyloxacyclododeca-4,8-diene-1,7-dione
  3-normeridamycin
  (3R,4S,6R)-4,6-dihydroxy-de-O-methyllasiodiplodin
  5-hydroxy-9-methyl-6-nonen-9-olide
  5-O-alpha-L-rhamnosyltylactone
  6-deoxypladienolide D
  6-epi-16-desmethyl-25,26-dihydrodictyostatin
  (6R)-6-hydroxy-3,4-dihydromilbemycin E
  7,8,9,16-tetrahydroxy-14-methoxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-benzo(c)(1)oxacyclotetradecin-1-one
  7-hydroxydihydroresorcylide
  7-O-malonyl macrolactin A
  7-O-succinyl macrolactin A
  8,9-dehydroneopeltolide
  8-deoxyhapalosin
  9-methylmigrastatin
  9-N,N-dimethylamino-9-deoxy-10,11,12,13-tetrahydroniddamycin
  A 82548A
  AB 400
  acidiscalide
  actinoallolide A
  aculeximycin
  acuminolide A
  acutiphycin
  AH 758
  aigialomycin D
  akaeolide
  alchivemycin A
  alchivemycin B
  aldgamycin E
  aldgamycin G
  aldgamycin I
  alirinomycin C
  altohyrtin C
  amantelide A
  amantelide B
  ammocidin
  ammocidin B
  ammocidin C
  ammocidin D
  amphidinolactone A
  amphidinolide A
  amphidinolide B1
  amphidinolide B2
  amphidinolide B6
  amphidinolide B7
  amphidinolide C
  amphidinolide C2
  amphidinolide F
  amphidinolide G
  amphidinolide H
  amphidinolide J
  amphidinolide K
  amphidinolide N
  amphidinolide O
  amphidinolide P
  amphidinolide Q
  amphidinolide T
  amphidinolide T1
  amphidinolide T2
  amphidinolide T4
  amphidinolide V
  amphidinolide W
  amphidinolide X
  amphidinolide Y
View node Amphotericin B Has associated genes Has associated diseases
  antibiotic 3874 H1
  antibiotic 3874 H3
  antibiotic AK 165-3
  antibiotic AS 40
View node Antimycin A Has associated genes Has associated diseases
  apicularen B
  aplyronine A
  aplyronine C
  apoptolidin
  apoptolidin A
  apoptolidin B
  apoptolidin C
  apoptolidin D
  apoptolidin E
  apoptolidin F
  apoptolidin G
  apoptolidinone
  archazolid A
  archazolid A-15-O-beta-D-glucopyranoside
  archazolid B Has associated genes Has associated diseases
  archazolide A
  arenicolide A
  arenicolide B
  arenicolide C
  arisostatin A
  arisostatin B
  aspergillide A
  aspergillide B
  aspergillide C
  aspergillide D
  aureoverticillactam
  auricin
  auriside A
  auriside B
  axenomycins
  azalomycin-F
  azalomycin F3a
  azalomycin F4
  azalomycin F4a
  azalomycin F5a
  bactericin
  bafilomycin A Has associated genes Has associated diseases
  bafilomycin A1 Has associated genes Has associated diseases
  bafilomycin B1
  bafilomycin C1
  bafilomycin C2
  bafilomycin D
  bafilomycin K
  bafilomycin L
  bafilomycin V1
  bahamaolide A
  bahamaolide B
  BAL 19403
  bastimolide A
  batatin VI
  belizeanolide
  benzopyrenomycin
  berkeleydione
  berkeleytrione
  biselyngbyaside
  biselyngbyolide A
  biselyngbyolide B
  bispolide A1
  bispolide B1
  bispolide B3
  bistheonellide A
  branimycin
  brasilinolide A
  brasilinolide B
  brasilinolide C
View node Brefeldin A Has associated genes Has associated diseases
View node Bryostatins Has associated genes Has associated diseases
  callipeltoside A
  callipeltoside B
  callipeltoside C
  callyspongiolide
View node Candicidin Has associated diseases
  candidaspongiolide
  candidin
  candihexins
  cannitracin
  carolacton
  CE-108
  CEM 101
  chainin
  chalcomycin
  chaxalactin A
  chaxalactin B
  chaxalactin C
  chivosazol A
  chivosazole F
  chloriolide
  chlorotonil A
  chondropsin A
  chondropsin B
  chondropsin C
  chondropsin D
  cis-(6RS,13RS)-3,3,10,10-tetramethyl-6,13-diphenyl-1,8-dioxa-4,11-diazacyclotetradecane-2,5,9,12-tetraone
  cladospolide A
  cladospolide B
  cladospolide C
  cladospolide D
  clavosolide A
  clavosolide B
  clavosolide C
  clavosolide D
  codinaeopsin
  concanamycin A Has associated genes Has associated diseases
  concanamycin B
  concanamycin C
  concanamycin D
  concanamycin E
  concanamycin F
  concanamycin G
  corifungin
  CP 163505
  CP2-disorazole C1
  CP-544372
  cruentaren A Has associated genes Has associated diseases
  cyanolide A
  cyathuscavin A
  cyathuscavin B
  cyathuscavin C
  cycloviracin B1
  cycloviracin B2
  cytospolide P
  cytovaricin
  cytovaricin B
  D-angolosamine
  decatromicin A
  decatromicin B
  dedesosaminyl-5-O-mycaminosyl-10,11-dihydromycinamicin IV
  defumarylhygrolidin
  De-N-methylpamamycin-593 A
  De-N-methylpamamycin-593 B
  de-O-methyllasiodiplodin
  desboroaplasmomycin
  deschlorocallipeltoside A
  desertomycin
  desertomycin A
  desertomycin B
  desertomycin E
  des-methyl, des-amino pateamine A
  desmethylhapalosin
  dicliripariside A
  dictyostatin
  didesmethyladinazolam
  dihydrochalcomycin
  dihydroresorcylide
  dinactin
  disorazole A1
  disorazole C1
  disorazole E1
  divergolide C
  divergolide D
  D-mycaminose
  dolabelide A
  dolabelide B
  dolabelide C
  dolabelide D
  E 7107
  EDP 420
  efomycine M
  elaiophylin
  elansolid A
  elansolid B1
  elansolid B2
  elansolid B3
  elansolid C1
  enigmazole A
  ent-pochonin J
View node Epothilones Has associated genes Has associated diseases
  epoxyphomalin A
  epoxyphomalin B
  epoxyphomalin C
  epoxyphomalin D
  epoxyphomalin E
View node Erythromycin Has associated genes Has associated diseases
  etamycin
  ethylene dodecanedioate
  etnangien
  eushearilide
  exiguolide
  faeriefungin
  faeriefungin A
  faeriefungin B
  FD 891
  FD 892
  FD 895
View node Filipin Has associated genes Has associated diseases
  flavofungin
  formamicin
  FR 900525
  fungichromin
  gamithromycin
  gannibamycin
  gargantulide A
  GERI 155
  gliomasolide C
  goniodomin A
  GW 708408
  GW 773546
  HA-1-92
  halichondrin A
  halichondrin B
  halichondrin C
  halstoctacosanolide A
  halstoctacosanolide B
  halstoctacosanolide C
  haterumalide B
  haterumalide NA
  hexadecanolide
  hexaene H-85
  HM 17
  HMR 3562
  HMR 3787
  homolasonolide A
  hurghadolide A
  hydroheptin
  hygrobafilomycin
  hygrolidin
  hygrolidin amide
  hygrolidin K1
  hygrolidin K2
  IB 96212
  iejimalide A
  iejimalide B
  iejimalide C
  iejimalide D
  inotilone
  iriomoteolide-1a
  iriomoteolide-1b
  iriomoteolide-1c
  Iriomoteolide-3a
  irumamycin
  isomandelalide A
  isomigrastatin
  isoswinholide B
View node Ivermectin Has associated genes Has associated diseases Has associated exposure references
  ivorenolide A
  ivorenolide B
  JA 20
  JBIR 06
  JBIR-100
  JBIR-129
  JBIR-139
  JBIR-19
  JBIR-20
  JBIR 52
View node Josamycin Has associated genes Has associated diseases
  juvenimicin C
  kabiramide G
  kabiramide I
  kabiramide J
  kabiramide K
  kabiramide L
  kitamycin A
  kitamycin B
  lactimidomycin
  langkolide
  lankacidins
  lasonolide A
  latrunculol A
  laulimalide
  lavendofuseomycin
  leinamycin
  leiodelide A
  leiodelide B
  leiodermatolide
  leucanicidin
  leucomycin A5
  leucomycin A7
View node Leucomycins Has associated genes Has associated diseases
  liposidolide A
  LL-F 28249lambda
  lobatamide A
  lobatamide C
  lobatamide D
  lobophorin A
  lobophorin B
  lobophorolide
  Lucensomycin
  lyngbouilloside
  lyngbouilloside aglycon
  lyngbyaloside B
  lyngbyaloside C
  lytophilippine A
  M 119-a
  macquarimicin A
  macquarimicin B
  macquarimicin C
  macrolactin A
  macrolactin E
  macrolactin N
  macrolactin S
  macrolactin T
  macrolactin U
  macrolactin W
  macrosphelide E
  macroviracin D
  madeirolide A
  maituolaimycin
  makinolide B
  maklamicin
  malolactomycin A
  malolactomycin C
  malolactomycin D
  malonylniphimycin
  manauealide A
  manauealide C
  mandelalide A
  mandelalide E
  mangromicin A
  mangromicin B
  mangromicin C
  mantidactolide A
  mantidactolide B
  marinisporolide C
  marinomycin A
  marinomycin B
  marinomycin C
  marinomycin D
  mathemycin A
  mathemycin B
View node Maytansine Has associated genes Has associated diseases
  MC 033
  MC 034
  medecamycin
  megalomicin, rhodosamine
  megalomycin C
  meilingmycin
  menisporopsin A
  menisporopsin B
View node Mepartricin
  meridamycin
  methyl nonactate
  methymycin
  methynolide
  migrastatin
  milbemycin Has associated genes Has associated diseases
  milbemycin alpha(31)
  milbemycin beta10
  milbemycin beta9
  milbemycin oxime Has associated diseases
  miniolutelide A
  miniolutelide B
View node Miocamycin
  mirabalin
  mirabilin (macrolide lactam)
  mirosamicin
  miyakolide
  MM 46115
  modiolide A
  modiolide B
  monactin
  monazomycin
  monazomycin B
  monorden Has associated genes Has associated diseases
  mycinamicins
  mycinamicin VIII
  mycolactone
  mycolactone A
  mycolactone B
  mycolactone S1
  mycolactone S2
  mycoticin A
  mycoticin B
  mycotrienol I
  Myxococcus xanthus antibiotic TA
  N-acetyl AB-400
  N-acetyl dihydrotetrafibricin methyl ester
  narbomycin
  narbonolide
View node Natamycin Has associated genes Has associated diseases
  Natular T30
  neaumycin
  neaumycin B
  neaumycin C
  nemadectin Has associated genes Has associated diseases
  neomethymycin
  neopeltolide
  neopentaene
  neopikromycin
  neurymenolide A
  neurymenolide B
  niddamycin
  niphithricin A
  niphithricin B
  nocardiopsin A
  nocardiopsin B
  nonactin
  notonesomycin A
  novamethymycin
  novapikromycin
  novolimus
  novonestmycin A
  novonestmycin B
  nuiapolide
View node Nystatin Has associated genes Has associated diseases
  oasomycin
  O-demethylchlorothricin
  O-demethylhydroxychlorothricin
View node Oleandomycin Has associated genes Has associated diseases
View node Oligomycins Has associated genes Has associated diseases
  omega-6-hexadecenlactone
  omega-pentadecalactone
  ossamycin
  oxacycloheptadec-10-ene-2-one
  oxacyclohexadecane-2,13-dione
  oxohygrolidin
  palmerolide A
  palmerolide C
  palmyrolide A
  pamamycin
  pamamycin-607
  pamamycin 621 A
  pamamycin-649B
  pandangolide 1
  pandangolide 3
  pandangolide 4
  pateamine A Has associated genes Has associated diseases
  patulolide C
  PC 766B
  PD 118576
  PD 118576-A1
  PD 118576-A2
  PD 118576-A3
  pectenotoxin-4
  pectenotoxin-8
  peloruside B
  peluroside A
  penarolide sulfate A2
  perimycin A
  phoracantholide I
  phorbaside A
  phorbaside B
  phorbaside C
  phorbaside D
  phorbaside E
  phorbaside F
  phorbaside G
  phorbaside H
  phorbaside I
  phormidolide
  phormidolide B
  phormidolide C
  phoxalone
  phthoramycin
  picromycin
  pladienolide B
  pladienolide D
  plakortenone
  plasmocin
  platenolide I
  platenolide II
  PN00053
  pochonin A
  pochonin C
  pochonin D
  poecillastrin A
  poecillastrin B
  poecillastrin C
  poecillastrin D
  polaramycin A
  polaramycin B
  polycavernoside A
  polycavernoside B
  premisakinolide A
  primycin
  prunustatin A
  pseudotrienic acid A
  pseudotrienic acid B
  pyrroindomycin A
  pyrroindomycin B
  pyrroindomycin B-Ac2
  pyrrolosporin A
  quinolidomicin A1
  quinolidomicin A2
  quinolidomicin B1
  R 176502
  RAD macrolide
  rediocide A
  rediocide G
  reidispongiolide A
  rhizopodin
  rhizoxin
  rimocidinolide methyl ester
  RK 397
  roritoxin E
  roxaticin
  RS 22A
  RS 22B
  RS 22C
  RU 004
  RU 56006
  RU 64399
  RU 66252
  RU 72366
  RU 76363
  saccharothriolide B
  salarin A
  salarin B
  salarin C
  Sch 38516
  Sch 38518
  Sch 39185
  Sch 642305
  Sch 725674
  S-deoxyleinamycin
  secomilbemycin C
  secomilbemycin D Has associated genes Has associated diseases
  sedecamycin
  seimatopolide A
  seimatopolide B
  setamycin
  shurimycin A
  shurimycin B
  simplextone A
  simplextone B
View node Sirolimus Has associated genes Has associated diseases
  SJA-95
  SNA 4606-1
  soraphen A
  SPA 6952A
  SPA 6952B
  spinetoram Has associated genes
  spinosad Has associated genes Has associated diseases
  spinosyn A Has associated genes
  spinosyn D
  spinosyn G
  spinosyn H
  spinosyn J
  spinosyn K
  spirastrellolide A
  spirastrellolide B
  spirastrellolide C
  spirastrellolide F methyl ester
  spirastrellolide G
  spongistatin 1
  spongistatin 6
  sporolide A
  sporostatin
  ST906 compound
  stambomycin A
  stambomycin B
  stambomycin C
  stambomycin D
  stellatoside B
  streptovaricin U
  sumalarin A
  sumalarin B
  sumalarin C
  superstolide A
  superstolide B
  swinholide I
  swinholide K
View node Tacrolimus Has associated genes Has associated diseases
  TAN 1323 C
  TAN 1323 D
  tartrolone C
  tausalarin C
  tedanolide
  tedanolide C
  terdecamycin
  tetrafibricin
  tetrafungin
  tetramycin
  tetrin A
  tetrin B
  tetrin C
  thuggacin A
  thuggacin B
  thuggacin C
  trichodermatide A
  trinactin
  tubelactomicin B
  tubelactomicin D
  tubelactomicin E
  tulearin
View node Tylosin
  ushikulide A
  ushikulide B
  VD 99-11
  venturicidin C
  verrucarin X
  versipelostatin Has associated genes Has associated diseases
  verticilactam
  VIC-105555
  vicenistatin
  viranamycin A
  viranamycin B
  virustomycin A
  VM 44857
  VM 44864
  VM 44865
  VM 44866
  wortmannilactone C
  xanthobaccin A
  YC-17 macrolide
  YM 32890A
  YM 32890B
  yokonolide A
  YS 822A
  zampanolide
  zeamine
  Zooxanthellamide Cs