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Chemical CD40 Antigens

Name CD40 Antigens
Equivalent Terms Antigen, CD40 | Antigen, CDw40 | Antigens, CD40 | CD40 Antigen | CDw40 Antigen | Receptor, TNFRSF5 | TNFRSF5 Receptor | Tumor Necrosis Factor Receptor Superfamily, Member 5
Definition Members of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. They are found on mature B-LYMPHOCYTES, some EPITHELIAL CELLS; and lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations in the CD40 antigen gene result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D019013
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Top ↑ Ancestors

1. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Antigens Has associated genes Has associated diseases Has associated exposure references Antigens, Surface Has associated diseases Antigens, Differentiation Antigens, Differentiation, B-Lymphocyte CD40 Antigens
2. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Biomarkers Has associated genes Has associated diseases Antigens, Differentiation Antigens, Differentiation, B-Lymphocyte CD40 Antigens

Top ↑ Descendants

None.