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Chemical 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine

Name 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
CAS Type 1 Name Piperazine, 1-(5-isoquinolinylsulfonyl)-2-methyl-, (2S-(1(R*(R*)), 2alpha, 3abeta, 7abeta))-
Equivalent Terms 1-(5-Isoquinolinylsulfonyl)-2-Methylpiperazine | H 7 | H-7
CAS Registry Number 84477-87-2
Definition A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
Structure 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
Top Interacting
Genes
MeSH® ID D019307
External Links
ChEBI
84477-87-2
ChemIDplus®
84477-87-2
Household Products Database
84477-87-2
PubChem
D019307
TOXLINE®
Query

Top ↑ Ancestors

1. Chemicals ← Organic Chemicals Has associated genes Has associated diseases Has associated exposure references ← Sulfur Compounds Has associated genes Has associated diseases Has associated exposure references ← Sulfones Has associated genes Has associated diseases Has associated exposure references ← Sulfonamides Has associated genes Has associated diseases Has associated exposure references ← 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Has associated genes Has associated diseases
2. Chemicals ← Heterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references ← Heterocyclic Compounds, 1-Ring Has associated genes Has associated diseases Has associated exposure references ← Piperazines Has associated genes Has associated diseases ← 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Has associated genes Has associated diseases
3. Chemicals ← Heterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references ← Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated exposure references ← Isoquinolines Has associated genes Has associated diseases ← 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Has associated genes Has associated diseases

Top ↑ Descendants

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine Has associated genes Has associated diseases
  1-(1-hydroxy-5-isoquinolinesulfonyl)homopiperazine
  1-(5-isoquinolinesulfonyl)piperazine
  1-(5-isoquinolinylsulfonyl)-3-methylpiperazine Has associated genes Has associated diseases
  2-methyl-1-((4-methyl-5-isoquinolinyl)sulfonyl)homopiperazine Has associated genes Has associated diseases
  fasudil Has associated genes Has associated diseases
  FSD-C10 compound
  HA 1100
  HMN 1180
  hydroxyfasudil Has associated genes Has associated diseases
  KN 04
  KN 62 Has associated genes Has associated diseases
  N-methyl-hydroxyfasudil