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Chemical Staurosporine

Name Staurosporine
CAS Type 1 Name 8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-
CAS Registry Number 62996-74-1
Definition An indolocarbazole that is a potent PROTEIN KINASE C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Structure Staurosporine
Top Interacting
Genes
MeSH® ID D019311
External Links

Top ↑ Ancestors

1. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Alkaloids Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Indole Alkaloids Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Staurosporine Has associated genes Has associated diseases Has associated phenotype references
2. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Heterocyclic Compounds, Fused-Ring Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Indoles Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Carbazoles Has associated genes Has associated diseases Has associated phenotype references Staurosporine Has associated genes Has associated diseases Has associated phenotype references
3. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Heterocyclic Compounds, Fused-Ring Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Indoles Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Indole Alkaloids Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Staurosporine Has associated genes Has associated diseases Has associated phenotype references
4. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Heterocyclic Compounds, Fused-Ring Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Heterocyclic Compounds, 3-Ring Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Carbazoles Has associated genes Has associated diseases Has associated phenotype references Staurosporine Has associated genes Has associated diseases Has associated phenotype references

Top ↑ Descendants

Staurosporine Has associated genes Has associated diseases Has associated phenotype references
  10'-(5''-((methoxycarbonyl)amino)-2'-methyl)phenylaminocarbonylstaurosporine
  3'-demethoxy-3'-hydroxy-4'-N-demethylstaurosporine
  3'-demethoxy-3'-hydroxystaurosporine
  3-hydroxy-4'-N-demethylstaurosporine
  3-hydroxy-4'-N-methylstaurosporine
  4'-demethylamino-4',5'-dihydroxystaurosporine
  4'-demethylamino-4'-hydroxystaurosporine
  4'-N-methyl-5'-hydroxystaurosporine
  5'-hydroxystaurosporine
  7-hydroxystaurosporine Has associated genes Has associated diseases Has associated phenotype references
  7-O-methyl-UCN 01
  7-oxo-3,8,9-trihydroxystaurosporine
  7-oxo-8,9-dihydroxy-4'-N-demethylstaurosporine
  7-oxostaurosporine
  AFN941
  CGP 42700
  CGP 44171A
  CGP 52421
  CGP 62221
  fradcarbazole A
  fradcarbazole B
  fradcarbazole C
  ICP-1 compound
  midostaurin Has associated genes Has associated diseases Has associated phenotype references
  N-carboxamido-staurosporine
  N-ethoxycarbonyl-7-oxostaurosporine
  N,N-dimethylstaurosporine
  SCH 47112
  selina-4(14),7(11)-diene-8,9-diol
  staurprimide