1. |
Okadaic Acid
|
superoxide anion generation
|
|
Okadaic Acid results in increased superoxide anion generation |
1: Rattus norvegicus |
Brain | Endothelial Cells | Cell Line |
2 genes: SOD1 | SOD2
|
1 |
2. |
Okadaic Acid
|
histamine secretion mediated by immunoglobulin
|
Ouabain
|
Okadaic Acid promotes the reaction [Ouabain results in increased histamine secretion mediated by immunoglobulin] |
1: Rattus norvegicus |
Mast Cells | Cells, Cultured |
|
1 |
3. |
Okadaic Acid
|
positive regulation of cell death
|
NADP
|
NADP inhibits the reaction [Okadaic Acid results in increased positive regulation of cell death] |
1: Homo sapiens |
Hep G2 Cells |
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
|
1 |
4. |
Okadaic Acid
|
protein serine/threonine phosphatase activity
|
SLCO1B3
| Sulfobromophthalein
|
Sulfobromophthalein inhibits the reaction [[SLCO1B3 protein results in increased susceptibility to Okadaic Acid] which results in decreased protein serine/threonine phosphatase activity] |
1: Homo sapiens |
HEK293 Cells |
5 genes: PPP1CA | PPP2CA | PPP2R1A | PPP4C | PPP5C
|
1 |
5. |
Okadaic Acid
|
apoptotic process
|
Ursodeoxycholic Acid
|
Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process] |
1: Homo sapiens |
HeLa Cells |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
1 |
6. |
Okadaic Acid
|
positive regulation of ion transmembrane transporter activity
|
Norepinephrine
|
Okadaic Acid promotes the reaction [Norepinephrine results in increased positive regulation of ion transmembrane transporter activity] |
1: Anas platyrhynchos |
Erythrocytes |
|
1 |
7. |
Okadaic Acid
|
positive regulation of cell death
|
CYP3A2
|
CYP3A2 protein promotes the reaction [Okadaic Acid results in increased positive regulation of cell death] |
1: Rattus norvegicus |
Hep G2 Cells |
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
|
1 |
8. |
Okadaic Acid
|
lipid catabolic process
|
|
Okadaic Acid results in increased lipid catabolic process |
1: Mus musculus |
Hippocampus | Cell Line |
4 genes: CES1D | LPL | PLA2G4A | PRDX6
|
1 |
9. |
Okadaic Acid
|
apoptotic process
|
Ursodeoxycholic Acid
|
Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process] |
1: Chlorocebus aethiops |
COS Cells |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
1 |
10. |
Okadaic Acid
|
intracellular distribution of mitochondria
|
|
Okadaic Acid affects intracellular distribution of mitochondria |
1: Rattus norvegicus |
Brain | Endothelial Cells | Cell Line |
6 genes: CLU | DNM1L | MAPT | MFN1 | MFN2 | OPA1
|
1 |
11. |
Okadaic Acid
|
apoptotic process
|
|
Okadaic Acid results in increased apoptotic process |
1: Homo sapiens |
Hepatocytes | Cell Line, Tumor |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
1 |
12. |
Okadaic Acid
|
regulation of mitochondrial membrane potential
|
|
Okadaic Acid results in decreased regulation of mitochondrial membrane potential |
1: Rattus norvegicus |
Hepatocytes | Cells, Cultured |
5 genes: BAX | BCL2 | SOD1 | SOD2 | UCP2
|
1 |
13. |
Okadaic Acid
|
superoxide dismutase activity
|
|
Okadaic Acid results in decreased superoxide dismutase activity |
1: Mus musculus |
Hippocampus | Cell Line |
2 genes: SOD1 | SOD2
|
1 |
14. |
Okadaic Acid
|
positive regulation of NF-kappaB transcription factor activity
|
|
Okadaic Acid results in increased positive regulation of NF-kappaB transcription factor activity |
1: Homo sapiens |
U937 Cells |
10 genes: AGT | APP | CLU | IL1B | IRAK1 | NFKB1 | NFKBIA | RELA | TNF | UBC
|
1 |
15. |
Okadaic Acid
|
response to oxidative stress
|
Glutathione
|
[Okadaic Acid results in increased response to oxidative stress] which results in decreased abundance of Glutathione |
1: Homo sapiens |
HeLa Cells |
21 genes: ABL1 | AKT1 | ALDH1A1 | APP | BCL2 | COX2 | DDIT3 | EPAS1 | JAK2 | MMP2 | NFKB1 | PCNA | PRDX5 | PRDX6 | PTGS2 | SELENOP | SOD1 | SOD2 | TOR1A | TP53 | TRP53
|
1 |
16. |
Okadaic Acid
|
response to oxidative stress
|
|
Okadaic Acid results in increased response to oxidative stress |
1: Homo sapiens |
HeLa Cells |
21 genes: ABL1 | AKT1 | ALDH1A1 | APP | BCL2 | COX2 | DDIT3 | EPAS1 | JAK2 | MMP2 | NFKB1 | PCNA | PRDX5 | PRDX6 | PTGS2 | SELENOP | SOD1 | SOD2 | TOR1A | TP53 | TRP53
|
1 |
17. |
Okadaic Acid
|
positive regulation of cell death
|
|
Okadaic Acid results in increased positive regulation of cell death |
1: Homo sapiens |
MCF-7 Cells |
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
|
1 |
18. |
Okadaic Acid
|
positive regulation of ion transmembrane transporter activity
|
N-(2-aminoethyl)-5-isoquinolinesulfonamide
| Rubidium
|
N-(2-aminoethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Okadaic Acid results in increased positive regulation of ion transmembrane transporter activity] which results in increased uptake of Rubidium] |
1: Anas platyrhynchos |
Erythrocytes |
|
1 |
19. |
Okadaic Acid
|
reactive oxygen species biosynthetic process
|
|
Okadaic Acid results in increased reactive oxygen species biosynthetic process |
1: Mus musculus |
Hippocampus | Cell Line |
|
1 |
20. |
Okadaic Acid
|
apoptotic process
|
|
Okadaic Acid results in increased apoptotic process |
|
Lymphocytes | Cell Line |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
1 |
21. |
Okadaic Acid
|
potassium ion export across plasma membrane
|
Chlorides
| Sodium Chloride
|
Okadaic Acid inhibits the reaction [Sodium Chloride deficiency promotes the reaction [Chlorides results in increased potassium ion export across plasma membrane]] |
1: Rana temporaria |
Erythrocytes | Cells, Cultured |
|
1 |
22. |
Okadaic Acid
|
cell migration
|
|
Okadaic Acid results in decreased cell migration |
1: Homo sapiens |
Cell Line, Tumor |
11 genes: CD44 | CDK1 | CXCL12 | FGFR4 | GSK3B | MMP2 | PDGFRA | PODXL | RPS6KB1 | THBS1 | VEGFA
|
1 |
23. |
Okadaic Acid
|
apoptotic process
|
Ursodeoxycholic Acid
|
Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process] |
1: Homo sapiens |
Bone and Bones | Cell Line, Tumor |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
1 |
24. |
Okadaic Acid
|
positive regulation of cell death
|
|
Okadaic Acid results in increased positive regulation of cell death |
1: Homo sapiens |
Hep G2 Cells |
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
|
2 |
25. |
Okadaic Acid
|
apoptotic DNA fragmentation
|
|
Okadaic Acid results in increased apoptotic DNA fragmentation |
1: Homo sapiens |
HeLa Cells |
1 gene: CASP3
|
1 |
26. |
Okadaic Acid
|
endoplasmic reticulum calcium ion homeostasis
|
|
Okadaic Acid affects endoplasmic reticulum calcium ion homeostasis |
1: Rattus norvegicus |
Brain | Endothelial Cells | Cell Line |
3 genes: BAX | BCL2 | ITPR1
|
1 |
27. |
Okadaic Acid
|
response to oxidative stress
|
|
Okadaic Acid results in increased response to oxidative stress |
1: Homo sapiens |
Bone and Bones | Cell Line, Tumor |
21 genes: ABL1 | AKT1 | ALDH1A1 | APP | BCL2 | COX2 | DDIT3 | EPAS1 | JAK2 | MMP2 | NFKB1 | PCNA | PRDX5 | PRDX6 | PTGS2 | SELENOP | SOD1 | SOD2 | TOR1A | TP53 | TRP53
|
1 |
28. |
Okadaic Acid
|
cellular response to drug
|
Bumetanide
|
[Okadaic Acid results in increased cellular response to drug] which results in increased activity of Bumetanide |
1: Anas platyrhynchos |
Erythrocytes |
14 genes: EGR1 | EP300 | GSTM1 | GSTM3 | HIF1A | HSPA5 | IL1B | MMP1 | NFE2L2 | NME1 | TFRC | TP53 | TXN1 | VEGFA
|
1 |
29. |
Okadaic Acid
|
positive regulation of cell death
|
CYP3A23/3A1
|
CYP3A23/3A1 protein inhibits the reaction [Okadaic Acid results in increased positive regulation of cell death] |
1: Rattus norvegicus |
Hep G2 Cells |
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
|
1 |
30. |
Okadaic Acid
|
cell death
|
Quercetin
|
Quercetin inhibits the reaction [Okadaic Acid results in increased cell death] |
1: Mus musculus |
Hippocampus | Cell Line |
1 gene: MAP3K10
|
1 |
31. |
Okadaic Acid
|
filopodium assembly
|
PPP1R9A
|
Okadaic Acid inhibits the reaction [PPP1R9A protein modified form results in increased filopodium assembly] |
1: Rattus norvegicus |
HEK293 Cells |
|
1 |
32. |
Okadaic Acid
|
tubulin deacetylation
|
|
Okadaic Acid results in increased tubulin deacetylation |
1: Rattus norvegicus |
Brain | Endothelial Cells | Cell Line |
|
1 |
33. |
Okadaic Acid
|
positive regulation of ion transmembrane transporter activity
|
N-(2-aminoethyl)-5-isoquinolinesulfonamide
|
N-(2-aminoethyl)-5-isoquinolinesulfonamide inhibits the reaction [Okadaic Acid results in increased positive regulation of ion transmembrane transporter activity] |
1: Anas platyrhynchos |
Erythrocytes |
|
1 |
34. |
Okadaic Acid
|
release of cytochrome c from mitochondria
|
|
Okadaic Acid results in increased release of cytochrome c from mitochondria |
1: Rattus norvegicus |
Brain | Endothelial Cells | Cell Line |
10 genes: BAX | BBC3 | BCL2 | CLU | DNM1L | FIS1 | JUN | SOD2 | TP53 | TRP53
|
1 |
35. |
Okadaic Acid
|
apoptotic process
|
|
Okadaic Acid results in increased apoptotic process |
1: Homo sapiens |
HeLa Cells |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
2 |
36. |
Okadaic Acid
|
apoptotic process
|
Norepinephrine
| Prazosin
|
[Prazosin co-treated with Norepinephrine] inhibits the reaction [Okadaic Acid results in increased apoptotic process] |
1: Rattus norvegicus |
Myocytes, Cardiac | Cells, Cultured |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
1 |
37. |
Okadaic Acid
|
apoptotic process
|
Colforsin
|
Colforsin inhibits the reaction [Okadaic Acid results in increased apoptotic process] |
1: Rattus norvegicus |
Myocytes, Cardiac | Cells, Cultured |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
1 |
38. |
Okadaic Acid
|
superoxide dismutase activity
|
Quercetin
|
Quercetin inhibits the reaction [Okadaic Acid results in decreased superoxide dismutase activity] |
1: Mus musculus |
Hippocampus | Cell Line |
2 genes: SOD1 | SOD2
|
1 |
39. |
Okadaic Acid
|
apoptotic process
|
|
Okadaic Acid results in increased apoptotic process |
1: Rattus norvegicus |
Myocytes, Cardiac | Cells, Cultured |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
1 |
40. |
Okadaic Acid
|
activation of protein kinase B activity
|
|
Okadaic Acid results in increased activation of protein kinase B activity |
1: Homo sapiens |
Prostate | Cell Line, Tumor |
3 genes: AKT1 | IGF1 | TXN
|
1 |
41. |
Okadaic Acid
|
calcium-mediated signaling
|
Ouabain
|
Okadaic Acid inhibits the reaction [Ouabain results in increased calcium-mediated signaling] |
1: Rattus norvegicus |
Mast Cells | Cells, Cultured |
4 genes: CALM1 | CALM2 | GRIN1 | TNF
|
1 |
42. |
Okadaic Acid
|
cellular response to drug
|
|
Okadaic Acid results in increased cellular response to drug |
1: Anas platyrhynchos |
Erythrocytes |
14 genes: EGR1 | EP300 | GSTM1 | GSTM3 | HIF1A | HSPA5 | IL1B | MMP1 | NFE2L2 | NME1 | TFRC | TP53 | TXN1 | VEGFA
|
1 |
43. |
Okadaic Acid
|
apoptotic process
|
Ursodeoxycholic Acid
|
Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process] |
1: Homo sapiens |
Hepatocytes | Cell Line, Tumor |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
1 |
44. |
Okadaic Acid
|
lipid catabolic process
|
Quercetin
|
Quercetin inhibits the reaction [Okadaic Acid results in increased lipid catabolic process] |
1: Mus musculus |
Hippocampus | Cell Line |
4 genes: CES1D | LPL | PLA2G4A | PRDX6
|
1 |
45. |
Okadaic Acid
|
apoptotic process
|
chelerythrine
|
chelerythrine promotes the reaction [Okadaic Acid results in increased apoptotic process] |
1: Rattus norvegicus |
Myocytes, Cardiac | Cells, Cultured |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
1 |
46. |
Okadaic Acid
|
apoptotic process
|
Ursodeoxycholic Acid
|
Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process] |
1: Rattus norvegicus |
Hepatocytes | Cells, Cultured |
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
|
1 |
47. |
Okadaic Acid
|
toxin catabolic process
|
NADP
|
[NADP results in increased toxin catabolic process] which results in increased metabolism of Okadaic Acid |
2: Homo sapiens | Rattus norvegicus |
Liver | Subcellular Fractions |
|
1 |
48. |
Okadaic Acid
|
DNA methylation
|
Ionomycin
| Tetradecanoylphorbol Acetate
|
Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased DNA methylation] |
1: Homo sapiens |
Veins | Blood | T-Lymphocytes | Cells, Cultured |
2 genes: DNMT1 | FOS
|
1 |
49. |
Okadaic Acid
|
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
|
|
Okadaic Acid results in increased positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus |
2: Homo sapiens | Scrobicularia plana |
COS Cells |
2 genes: RELA | RXRA
|
1 |
50. |
Okadaic Acid
|
apoptotic DNA fragmentation
|
|
Okadaic Acid results in increased apoptotic DNA fragmentation |
1: Rattus norvegicus |
Hepatocytes | Cells, Cultured |
1 gene: CASP3
|
1 |