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Chemical Okadaic Acid

1–50 of 105 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. Okadaic Acid superoxide anion generation Okadaic Acid results in increased superoxide anion generation 1: Rattus norvegicus Brain | Endothelial Cells | Cell Line
2 genes: SOD1 | SOD2
1
2. Okadaic Acid histamine secretion mediated by immunoglobulin Ouabain Okadaic Acid promotes the reaction [Ouabain results in increased histamine secretion mediated by immunoglobulin] 1: Rattus norvegicus Mast Cells | Cells, Cultured   1
3. Okadaic Acid positive regulation of cell death NADP NADP inhibits the reaction [Okadaic Acid results in increased positive regulation of cell death] 1: Homo sapiens Hep G2 Cells
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
1
4. Okadaic Acid protein serine/threonine phosphatase activity SLCO1B3 | Sulfobromophthalein Sulfobromophthalein inhibits the reaction [[SLCO1B3 protein results in increased susceptibility to Okadaic Acid] which results in decreased protein serine/threonine phosphatase activity] 1: Homo sapiens HEK293 Cells
5 genes: PPP1CA | PPP2CA | PPP2R1A | PPP4C | PPP5C
1
5. Okadaic Acid apoptotic process Ursodeoxycholic Acid Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process] 1: Homo sapiens HeLa Cells
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
6. Okadaic Acid positive regulation of ion transmembrane transporter activity Norepinephrine Okadaic Acid promotes the reaction [Norepinephrine results in increased positive regulation of ion transmembrane transporter activity] 1: Anas platyrhynchos Erythrocytes   1
7. Okadaic Acid positive regulation of cell death CYP3A2 CYP3A2 protein promotes the reaction [Okadaic Acid results in increased positive regulation of cell death] 1: Rattus norvegicus Hep G2 Cells
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
1
8. Okadaic Acid lipid catabolic process Okadaic Acid results in increased lipid catabolic process 1: Mus musculus Hippocampus | Cell Line
4 genes: CES1D | LPL | PLA2G4A | PRDX6
1
9. Okadaic Acid apoptotic process Ursodeoxycholic Acid Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process] 1: Chlorocebus aethiops COS Cells
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
10. Okadaic Acid intracellular distribution of mitochondria Okadaic Acid affects intracellular distribution of mitochondria 1: Rattus norvegicus Brain | Endothelial Cells | Cell Line
6 genes: CLU | DNM1L | MAPT | MFN1 | MFN2 | OPA1
1
11. Okadaic Acid apoptotic process Okadaic Acid results in increased apoptotic process 1: Homo sapiens Hepatocytes | Cell Line, Tumor
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
12. Okadaic Acid regulation of mitochondrial membrane potential Okadaic Acid results in decreased regulation of mitochondrial membrane potential 1: Rattus norvegicus Hepatocytes | Cells, Cultured
5 genes: BAX | BCL2 | SOD1 | SOD2 | UCP2
1
13. Okadaic Acid superoxide dismutase activity Okadaic Acid results in decreased superoxide dismutase activity 1: Mus musculus Hippocampus | Cell Line
2 genes: SOD1 | SOD2
1
14. Okadaic Acid positive regulation of NF-kappaB transcription factor activity Okadaic Acid results in increased positive regulation of NF-kappaB transcription factor activity 1: Homo sapiens U937 Cells
10 genes: AGT | APP | CLU | IL1B | IRAK1 | NFKB1 | NFKBIA | RELA | TNF | UBC
1
15. Okadaic Acid response to oxidative stress Glutathione [Okadaic Acid results in increased response to oxidative stress] which results in decreased abundance of Glutathione 1: Homo sapiens HeLa Cells
21 genes: ABL1 | AKT1 | ALDH1A1 | APP | BCL2 | COX2 | DDIT3 | EPAS1 | JAK2 | MMP2 | NFKB1 | PCNA | PRDX5 | PRDX6 | PTGS2 | SELENOP | SOD1 | SOD2 | TOR1A | TP53 | TRP53
1
16. Okadaic Acid response to oxidative stress Okadaic Acid results in increased response to oxidative stress 1: Homo sapiens HeLa Cells
21 genes: ABL1 | AKT1 | ALDH1A1 | APP | BCL2 | COX2 | DDIT3 | EPAS1 | JAK2 | MMP2 | NFKB1 | PCNA | PRDX5 | PRDX6 | PTGS2 | SELENOP | SOD1 | SOD2 | TOR1A | TP53 | TRP53
1
17. Okadaic Acid positive regulation of cell death Okadaic Acid results in increased positive regulation of cell death 1: Homo sapiens MCF-7 Cells
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
1
18. Okadaic Acid positive regulation of ion transmembrane transporter activity N-(2-aminoethyl)-5-isoquinolinesulfonamide | Rubidium N-(2-aminoethyl)-5-isoquinolinesulfonamide inhibits the reaction [[Okadaic Acid results in increased positive regulation of ion transmembrane transporter activity] which results in increased uptake of Rubidium] 1: Anas platyrhynchos Erythrocytes   1
19. Okadaic Acid reactive oxygen species biosynthetic process Okadaic Acid results in increased reactive oxygen species biosynthetic process 1: Mus musculus Hippocampus | Cell Line   1
20. Okadaic Acid apoptotic process Okadaic Acid results in increased apoptotic process Lymphocytes | Cell Line
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
21. Okadaic Acid potassium ion export across plasma membrane Chlorides | Sodium Chloride Okadaic Acid inhibits the reaction [Sodium Chloride deficiency promotes the reaction [Chlorides results in increased potassium ion export across plasma membrane]] 1: Rana temporaria Erythrocytes | Cells, Cultured   1
22. Okadaic Acid cell migration Okadaic Acid results in decreased cell migration 1: Homo sapiens Cell Line, Tumor
11 genes: CD44 | CDK1 | CXCL12 | FGFR4 | GSK3B | MMP2 | PDGFRA | PODXL | RPS6KB1 | THBS1 | VEGFA
1
23. Okadaic Acid apoptotic process Ursodeoxycholic Acid Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process] 1: Homo sapiens Bone and Bones | Cell Line, Tumor
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
24. Okadaic Acid positive regulation of cell death Okadaic Acid results in increased positive regulation of cell death 1: Homo sapiens Hep G2 Cells
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
2
25. Okadaic Acid apoptotic DNA fragmentation Okadaic Acid results in increased apoptotic DNA fragmentation 1: Homo sapiens HeLa Cells 1 gene: CASP3 1
26. Okadaic Acid endoplasmic reticulum calcium ion homeostasis Okadaic Acid affects endoplasmic reticulum calcium ion homeostasis 1: Rattus norvegicus Brain | Endothelial Cells | Cell Line
3 genes: BAX | BCL2 | ITPR1
1
27. Okadaic Acid response to oxidative stress Okadaic Acid results in increased response to oxidative stress 1: Homo sapiens Bone and Bones | Cell Line, Tumor
21 genes: ABL1 | AKT1 | ALDH1A1 | APP | BCL2 | COX2 | DDIT3 | EPAS1 | JAK2 | MMP2 | NFKB1 | PCNA | PRDX5 | PRDX6 | PTGS2 | SELENOP | SOD1 | SOD2 | TOR1A | TP53 | TRP53
1
28. Okadaic Acid cellular response to drug Bumetanide [Okadaic Acid results in increased cellular response to drug] which results in increased activity of Bumetanide 1: Anas platyrhynchos Erythrocytes
14 genes: EGR1 | EP300 | GSTM1 | GSTM3 | HIF1A | HSPA5 | IL1B | MMP1 | NFE2L2 | NME1 | TFRC | TP53 | TXN1 | VEGFA
1
29. Okadaic Acid positive regulation of cell death CYP3A23/3A1 CYP3A23/3A1 protein inhibits the reaction [Okadaic Acid results in increased positive regulation of cell death] 1: Rattus norvegicus Hep G2 Cells
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
1
30. Okadaic Acid cell death Quercetin Quercetin inhibits the reaction [Okadaic Acid results in increased cell death] 1: Mus musculus Hippocampus | Cell Line 1 gene: MAP3K10 1
31. Okadaic Acid filopodium assembly PPP1R9A Okadaic Acid inhibits the reaction [PPP1R9A protein modified form results in increased filopodium assembly] 1: Rattus norvegicus HEK293 Cells   1
32. Okadaic Acid tubulin deacetylation Okadaic Acid results in increased tubulin deacetylation 1: Rattus norvegicus Brain | Endothelial Cells | Cell Line   1
33. Okadaic Acid positive regulation of ion transmembrane transporter activity N-(2-aminoethyl)-5-isoquinolinesulfonamide N-(2-aminoethyl)-5-isoquinolinesulfonamide inhibits the reaction [Okadaic Acid results in increased positive regulation of ion transmembrane transporter activity] 1: Anas platyrhynchos Erythrocytes   1
34. Okadaic Acid release of cytochrome c from mitochondria Okadaic Acid results in increased release of cytochrome c from mitochondria 1: Rattus norvegicus Brain | Endothelial Cells | Cell Line
10 genes: BAX | BBC3 | BCL2 | CLU | DNM1L | FIS1 | JUN | SOD2 | TP53 | TRP53
1
35. Okadaic Acid apoptotic process Okadaic Acid results in increased apoptotic process 1: Homo sapiens HeLa Cells
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
2
36. Okadaic Acid apoptotic process Norepinephrine | Prazosin [Prazosin co-treated with Norepinephrine] inhibits the reaction [Okadaic Acid results in increased apoptotic process] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
37. Okadaic Acid apoptotic process Colforsin Colforsin inhibits the reaction [Okadaic Acid results in increased apoptotic process] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
38. Okadaic Acid superoxide dismutase activity Quercetin Quercetin inhibits the reaction [Okadaic Acid results in decreased superoxide dismutase activity] 1: Mus musculus Hippocampus | Cell Line
2 genes: SOD1 | SOD2
1
39. Okadaic Acid apoptotic process Okadaic Acid results in increased apoptotic process 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
40. Okadaic Acid activation of protein kinase B activity Okadaic Acid results in increased activation of protein kinase B activity 1: Homo sapiens Prostate | Cell Line, Tumor
3 genes: AKT1 | IGF1 | TXN
1
41. Okadaic Acid calcium-mediated signaling Ouabain Okadaic Acid inhibits the reaction [Ouabain results in increased calcium-mediated signaling] 1: Rattus norvegicus Mast Cells | Cells, Cultured
4 genes: CALM1 | CALM2 | GRIN1 | TNF
1
42. Okadaic Acid cellular response to drug Okadaic Acid results in increased cellular response to drug 1: Anas platyrhynchos Erythrocytes
14 genes: EGR1 | EP300 | GSTM1 | GSTM3 | HIF1A | HSPA5 | IL1B | MMP1 | NFE2L2 | NME1 | TFRC | TP53 | TXN1 | VEGFA
1
43. Okadaic Acid apoptotic process Ursodeoxycholic Acid Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process] 1: Homo sapiens Hepatocytes | Cell Line, Tumor
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
44. Okadaic Acid lipid catabolic process Quercetin Quercetin inhibits the reaction [Okadaic Acid results in increased lipid catabolic process] 1: Mus musculus Hippocampus | Cell Line
4 genes: CES1D | LPL | PLA2G4A | PRDX6
1
45. Okadaic Acid apoptotic process chelerythrine chelerythrine promotes the reaction [Okadaic Acid results in increased apoptotic process] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
46. Okadaic Acid apoptotic process Ursodeoxycholic Acid Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process] 1: Rattus norvegicus Hepatocytes | Cells, Cultured
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
47. Okadaic Acid toxin catabolic process NADP [NADP results in increased toxin catabolic process] which results in increased metabolism of Okadaic Acid 2: Homo sapiens | Rattus norvegicus Liver | Subcellular Fractions   1
48. Okadaic Acid DNA methylation Ionomycin | Tetradecanoylphorbol Acetate Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased DNA methylation] 1: Homo sapiens Veins | Blood | T-Lymphocytes | Cells, Cultured
2 genes: DNMT1 | FOS
1
49. Okadaic Acid positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus Okadaic Acid results in increased positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus 2: Homo sapiens | Scrobicularia plana COS Cells
2 genes: RELA | RXRA
1
50. Okadaic Acid apoptotic DNA fragmentation Okadaic Acid results in increased apoptotic DNA fragmentation 1: Rattus norvegicus Hepatocytes | Cells, Cultured 1 gene: CASP3 1
1–50 of 105 results.