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Chemical Okadaic Acid

1–50 of 105 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. Okadaic Acid positive regulation of apoptotic process Okadaic Acid affects positive regulation of apoptotic process 1: Mus musculus Brain | Neurons | Cells, Cultured
46 genes: ABL1 | AKT1 | ALDH1A1 | ANXA5 | ARHGEF17 | BAX | BBC3 | BCL2L11 | CASP3 | CASP8 | CASP9 | CLU | CREB1 | CTNNB1 | CYP1B1 | DDIT3 | DNM1L | EGLN1 | FOSL1 | FOXO3 | GRIN1 | GSK3B | HIF1A | HTRA2 | IL1B | JAK2 | JUN | MAP3K10 | MAPK8 | MLLT11 | MMP2 | NGF | PDIA3 | PLA2G4A | PPP2CA | PTGS2 | PTN | RELA | RXRA | SOD1 | TNF | TNFSF10 | TOP2A | TP53 | TRP53 | UBC
1
2. Okadaic Acid calcium import into the mitochondrion Okadaic Acid affects calcium import into the mitochondrion 1: Rattus norvegicus Brain | Endothelial Cells | Cell Line 1 gene: OPA1 1
3. Okadaic Acid apoptotic process Okadaic Acid results in increased apoptotic process 1: Chlorocebus aethiops COS Cells
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
4. Okadaic Acid calcium-mediated signaling Ouabain Okadaic Acid inhibits the reaction [Ouabain results in increased calcium-mediated signaling] 1: Rattus norvegicus Mast Cells | Cells, Cultured
4 genes: CALM1 | CALM2 | GRIN1 | TNF
1
5. Okadaic Acid positive regulation of cell death NADP NADP inhibits the reaction [Okadaic Acid results in increased positive regulation of cell death] 1: Homo sapiens Hep G2 Cells
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
1
6. Okadaic Acid positive regulation of apoptotic process BBC3 BBC3 protein affects the reaction [Okadaic Acid affects positive regulation of apoptotic process] 1: Mus musculus Brain | Neurons | Cells, Cultured
46 genes: ABL1 | AKT1 | ALDH1A1 | ANXA5 | ARHGEF17 | BAX | BBC3 | BCL2L11 | CASP3 | CASP8 | CASP9 | CLU | CREB1 | CTNNB1 | CYP1B1 | DDIT3 | DNM1L | EGLN1 | FOSL1 | FOXO3 | GRIN1 | GSK3B | HIF1A | HTRA2 | IL1B | JAK2 | JUN | MAP3K10 | MAPK8 | MLLT11 | MMP2 | NGF | PDIA3 | PLA2G4A | PPP2CA | PTGS2 | PTN | RELA | RXRA | SOD1 | TNF | TNFSF10 | TOP2A | TP53 | TRP53 | UBC
1
7. Okadaic Acid apoptotic DNA fragmentation Okadaic Acid results in increased apoptotic DNA fragmentation 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured 1 gene: CASP3 1
8. Okadaic Acid apoptotic process Benzo(a)pyrene | Estradiol Okadaic Acid inhibits the reaction [Estradiol inhibits the reaction [Benzo(a)pyrene results in increased apoptotic process]] 1: Homo sapiens Hep G2 Cells
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
9. Okadaic Acid apoptotic process Okadaic Acid results in increased apoptotic process 1: Rattus norvegicus Hepatocytes | Cells, Cultured
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
10. Okadaic Acid positive regulation of ion transmembrane transporter activity Okadaic Acid results in increased positive regulation of ion transmembrane transporter activity 1: Anas platyrhynchos Erythrocytes   1
11. Okadaic Acid alpha-tubulin acetylation Okadaic Acid results in decreased alpha-tubulin acetylation 1: Rattus norvegicus Brain | Endothelial Cells | Cell Line   1
12. Okadaic Acid regulation of mitochondrial membrane potential Okadaic Acid results in decreased regulation of mitochondrial membrane potential 1: Rattus norvegicus Hepatocytes | Cells, Cultured
5 genes: BAX | BCL2 | SOD1 | SOD2 | UCP2
1
13. Okadaic Acid reactive oxygen species biosynthetic process Quercetin Quercetin inhibits the reaction [Okadaic Acid results in increased reactive oxygen species biosynthetic process] 1: Mus musculus Hippocampus | Cell Line   1
14. Okadaic Acid positive regulation of ion transmembrane transporter activity Norepinephrine | Rubidium Okadaic Acid promotes the reaction [[Norepinephrine results in increased positive regulation of ion transmembrane transporter activity] which results in increased uptake of Rubidium] 1: Anas platyrhynchos Erythrocytes   1
15. Okadaic Acid lipid catabolic process Quercetin Quercetin inhibits the reaction [Okadaic Acid results in increased lipid catabolic process] 1: Mus musculus Hippocampus | Cell Line
4 genes: CES1D | LPL | PLA2G4A | PRDX6
1
16. Okadaic Acid apoptotic DNA fragmentation Ursodeoxycholic Acid Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic DNA fragmentation] 1: Rattus norvegicus Hepatocytes | Cells, Cultured 1 gene: CASP3 1
17. Okadaic Acid filopodium assembly PPP1R9A Okadaic Acid inhibits the reaction [PPP1R9A protein modified form results in increased filopodium assembly] 1: Rattus norvegicus HEK293 Cells   1
18. Okadaic Acid apoptotic process Benzo(a)pyrene | Tetrachlorodibenzodioxin Okadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased apoptotic process]] 1: Homo sapiens Hep G2 Cells
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
19. Okadaic Acid apoptotic process N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Okadaic Acid results in increased apoptotic process] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
20. Okadaic Acid cell death Okadaic Acid results in increased cell death 1: Rattus norvegicus Brain | Endothelial Cells | Cell Line 1 gene: MAP3K10 1
21. Okadaic Acid positive regulation of cell death Okadaic Acid results in increased positive regulation of cell death 1: Homo sapiens MCF-7 Cells
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
1
22. Okadaic Acid apoptotic process Norepinephrine | Propranolol [Propranolol co-treated with Norepinephrine] inhibits the reaction [Okadaic Acid results in increased apoptotic process] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
23. Okadaic Acid positive regulation of apoptotic process TRP53 TRP53 protein affects the reaction [Okadaic Acid affects positive regulation of apoptotic process] 1: Mus musculus Brain | Neurons | Cells, Cultured
46 genes: ABL1 | AKT1 | ALDH1A1 | ANXA5 | ARHGEF17 | BAX | BBC3 | BCL2L11 | CASP3 | CASP8 | CASP9 | CLU | CREB1 | CTNNB1 | CYP1B1 | DDIT3 | DNM1L | EGLN1 | FOSL1 | FOXO3 | GRIN1 | GSK3B | HIF1A | HTRA2 | IL1B | JAK2 | JUN | MAP3K10 | MAPK8 | MLLT11 | MMP2 | NGF | PDIA3 | PLA2G4A | PPP2CA | PTGS2 | PTN | RELA | RXRA | SOD1 | TNF | TNFSF10 | TOP2A | TP53 | TRP53 | UBC
1
24. Okadaic Acid cell proliferation Clofibrate Okadaic Acid inhibits the reaction [Clofibrate results in decreased cell proliferation] 1: Rattus norvegicus Hepatocytes | Cell Line, Tumor
21 genes: ADRA1B | AKT1 | BAX | BCL2 | CDK1 | CREBBP | CTNNB1 | DAB2 | DLG1 | ELN | GSK3B | IGF1 | MAPRE2 | PCNA | RAF1 | SDCBP2 | TNF | TOP2A | TP53 | TXN | VEGFA
1
25. Okadaic Acid positive regulation of ion transmembrane transporter activity staurosporine aglycone staurosporine aglycone inhibits the reaction [Okadaic Acid results in increased positive regulation of ion transmembrane transporter activity] 1: Anas platyrhynchos Erythrocytes   1
26. Okadaic Acid response to oxidative stress Okadaic Acid inhibits the reaction [Okadaic Acid results in increased response to oxidative stress] 1: Homo sapiens Bone and Bones | Cell Line, Tumor
21 genes: ABL1 | AKT1 | ALDH1A1 | APP | BCL2 | COX2 | DDIT3 | EPAS1 | JAK2 | MMP2 | NFKB1 | PCNA | PRDX5 | PRDX6 | PTGS2 | SELENOP | SOD1 | SOD2 | TOR1A | TP53 | TRP53
1
27. Okadaic Acid apoptotic process BCL2 [Okadaic Acid results in increased apoptotic process] which results in increased phosphorylation of BCL2 protein Lymphocytes | Cell Line
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
28. Okadaic Acid protein serine/threonine phosphatase activity SLCO1B1 [SLCO1B1 protein results in increased susceptibility to Okadaic Acid] which results in decreased protein serine/threonine phosphatase activity 1: Homo sapiens HEK293 Cells
5 genes: PPP1CA | PPP2CA | PPP2R1A | PPP4C | PPP5C
1
29. Okadaic Acid toxin catabolic process NADP [NADP results in increased toxin catabolic process] which results in increased metabolism of Okadaic Acid 2: Homo sapiens | Rattus norvegicus Liver | Subcellular Fractions   1
30. Okadaic Acid protein serine/threonine phosphatase activity SLCO1B3 [SLCO1B3 protein results in increased susceptibility to Okadaic Acid] which results in decreased protein serine/threonine phosphatase activity 1: Homo sapiens HEK293 Cells
5 genes: PPP1CA | PPP2CA | PPP2R1A | PPP4C | PPP5C
1
31. Okadaic Acid apoptotic process Okadaic Acid results in increased apoptotic process 1: Homo sapiens U937 Cells
53 genes: ABL1 | AKT1 | APP | BAX | BBC3 | BCL2 | BCL2L11 | BCL2L14 | CASP10 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | DAB2 | DDIT3 | EGLN3 | EP300 | ERN1 | FIS1 | FOXO3 | GAPDH | GJA1 | HTRA2 | IER3 | IL1B | ITPR1 | JAK2 | MAP3K10 | MAPK1 | MAPK3 | MAPT | MFN2 | NFKB1 | NFKBIA | NR3C1 | OPA1 | PARP1 | PPP2CA | PPP2R1A | PRDX5 | RAD21 | RAF1 | RB1 | RPS6KB1 | TAX1BP1 | TF | TNF | TNFSF10 | TP53 | TRP53 | UBE2D3 | XBP1
1
32. Okadaic Acid regulation of vascular permeability mustard oil | sodium arsenite Okadaic Acid inhibits the reaction [sodium arsenite promotes the reaction [mustard oil affects regulation of vascular permeability]] 1: Mus musculus Microvessels   1
33. Okadaic Acid intracellular distribution of mitochondria Okadaic Acid affects intracellular distribution of mitochondria 1: Rattus norvegicus Brain | Endothelial Cells | Cell Line
6 genes: CLU | DNM1L | MAPT | MFN1 | MFN2 | OPA1
1
34. Okadaic Acid glutathione biosynthetic process Quercetin Quercetin inhibits the reaction [Okadaic Acid results in decreased glutathione biosynthetic process] 1: Mus musculus Hippocampus | Cell Line   1
35. Okadaic Acid positive regulation of NF-kappaB transcription factor activity SOD2 SOD2 protein inhibits the reaction [Okadaic Acid results in increased positive regulation of NF-kappaB transcription factor activity] 1: Homo sapiens MCF-7 Cells
9 genes: AGT | APP | CLU | IL1B | IRAK1 | NFKB1 | RELA | TNF | UBC
1
36. Okadaic Acid cell death Okadaic Acid results in increased cell death 1: Mus musculus Hippocampus | Cell Line 1 gene: MAP3K10 1
37. Okadaic Acid positive regulation of NF-kappaB transcription factor activity Okadaic Acid results in increased positive regulation of NF-kappaB transcription factor activity 1: Homo sapiens MCF-7 Cells
9 genes: AGT | APP | CLU | IL1B | IRAK1 | NFKB1 | RELA | TNF | UBC
1
38. Okadaic Acid activation of protein kinase B activity Okadaic Acid results in increased activation of protein kinase B activity 1: Homo sapiens Prostate | Cell Line, Tumor
3 genes: AKT1 | IGF1 | TXN
1
39. Okadaic Acid positive regulation of cell death CYP3A23/3A1 CYP3A23/3A1 protein inhibits the reaction [Okadaic Acid results in increased positive regulation of cell death] 1: Rattus norvegicus Hep G2 Cells
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
1
40. Okadaic Acid positive regulation of ion transmembrane transporter activity Rubidium | staurosporine aglycone staurosporine aglycone inhibits the reaction [[Okadaic Acid results in increased positive regulation of ion transmembrane transporter activity] which results in increased uptake of Rubidium] 1: Anas platyrhynchos Erythrocytes   1
41. Okadaic Acid lipid catabolic process Okadaic Acid results in increased lipid catabolic process 1: Mus musculus Hippocampus | Cell Line
4 genes: CES1D | LPL | PLA2G4A | PRDX6
1
42. Okadaic Acid positive regulation of cell death Okadaic Acid results in increased positive regulation of cell death 1: Homo sapiens Hep G2 Cells
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
2
43. Okadaic Acid positive regulation of ion transmembrane transporter activity Norepinephrine | Propranolol Okadaic Acid inhibits the reaction [Propranolol inhibits the reaction [Norepinephrine results in increased positive regulation of ion transmembrane transporter activity]] 1: Anas platyrhynchos Erythrocytes   1
44. Okadaic Acid cellular response to xenobiotic stimulus Okadaic Acid results in increased cellular response to xenobiotic stimulus 2: Homo sapiens | Scrobicularia plana COS Cells
3 genes: GSTP1 | PCNA | RB1
1
45. Okadaic Acid positive regulation of ion transmembrane transporter activity Bumetanide Bumetanide inhibits the reaction [Okadaic Acid results in increased positive regulation of ion transmembrane transporter activity] 1: Anas platyrhynchos Erythrocytes   1
46. Okadaic Acid protein serine/threonine phosphatase activity SLCO1B1 | Sulfobromophthalein Sulfobromophthalein inhibits the reaction [[SLCO1B1 protein results in increased susceptibility to Okadaic Acid] which results in decreased protein serine/threonine phosphatase activity] 1: Homo sapiens HEK293 Cells
5 genes: PPP1CA | PPP2CA | PPP2R1A | PPP4C | PPP5C
1
47. Okadaic Acid cell migration Okadaic Acid results in decreased cell migration 1: Homo sapiens Cell Line, Tumor
11 genes: CD44 | CDK1 | CXCL12 | FGFR4 | GSK3B | MMP2 | PDGFRA | PODXL | RPS6KB1 | THBS1 | VEGFA
1
48. Okadaic Acid glutathione biosynthetic process Okadaic Acid results in decreased glutathione biosynthetic process 1: Mus musculus Hippocampus | Cell Line   1
49. Okadaic Acid positive regulation of ion transmembrane transporter activity Rubidium [Okadaic Acid results in increased positive regulation of ion transmembrane transporter activity] which results in increased uptake of Rubidium 1: Anas platyrhynchos Erythrocytes   1
50. Okadaic Acid positive regulation of cell death CYP3A2 CYP3A2 protein promotes the reaction [Okadaic Acid results in increased positive regulation of cell death] 1: Rattus norvegicus Hep G2 Cells
10 genes: ACOX2 | BCL2L11 | EGR1 | EP300 | GRIN1 | HTRA2 | IL1B | PDX1 | PTGS2 | UCP2
1
1–50 of 105 results.