Okadaic Acid - Phenotypes

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	Chemical	Phenotype	Co-Mentioned Terms	Interaction	Organisms	Anatomy	Inference Network	References
1.	Okadaic Acid	apoptotic DNA fragmentation		Okadaic Acid results in increased apoptotic DNA fragmentation	1: Rattus norvegicus	Myocytes, Cardiac \| Cells, Cultured	1 gene: CASP3	1
2.	Okadaic Acid	apoptotic process		Okadaic Acid results in increased apoptotic process	1: Rattus norvegicus	Myocytes, Cardiac \| Cells, Cultured	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
3.	Okadaic Acid	apoptotic process	Norepinephrine \| Propranolol	[Propranolol co-treated with Norepinephrine] inhibits the reaction [Okadaic Acid results in increased apoptotic process]	1: Rattus norvegicus	Myocytes, Cardiac \| Cells, Cultured	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
4.	Okadaic Acid	apoptotic process	Norepinephrine \| Prazosin	[Prazosin co-treated with Norepinephrine] inhibits the reaction [Okadaic Acid results in increased apoptotic process]	1: Rattus norvegicus	Myocytes, Cardiac \| Cells, Cultured	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
5.	Okadaic Acid	apoptotic process	Colforsin	Colforsin inhibits the reaction [Okadaic Acid results in increased apoptotic process]	1: Rattus norvegicus	Myocytes, Cardiac \| Cells, Cultured	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
6.	Okadaic Acid	apoptotic process	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide	N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Okadaic Acid results in increased apoptotic process]	1: Rattus norvegicus	Myocytes, Cardiac \| Cells, Cultured	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
7.	Okadaic Acid	apoptotic process	chelerythrine	chelerythrine promotes the reaction [Okadaic Acid results in increased apoptotic process]	1: Rattus norvegicus	Myocytes, Cardiac \| Cells, Cultured	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
8.	Okadaic Acid	apoptotic process		Okadaic Acid results in increased apoptotic process	1: Homo sapiens	U937 Cells	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
9.	Okadaic Acid	histamine secretion mediated by immunoglobulin	Ouabain	Okadaic Acid promotes the reaction [Ouabain results in increased histamine secretion mediated by immunoglobulin]	1: Rattus norvegicus	Mast Cells \| Cells, Cultured		1
10.	Okadaic Acid	calcium-mediated signaling	Ouabain	Okadaic Acid inhibits the reaction [Ouabain results in increased calcium-mediated signaling]	1: Rattus norvegicus	Mast Cells \| Cells, Cultured	4 genes: CALM1 \| CALM2 \| GRIN1 \| TNF	1
11.	Okadaic Acid	apoptotic process		Okadaic Acid results in increased apoptotic process	1: Homo sapiens	Hepatocytes \| Cell Line, Tumor	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
12.	Okadaic Acid	apoptotic process		Okadaic Acid results in increased apoptotic process	1: Homo sapiens	Bone and Bones \| Cell Line, Tumor	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
13.	Okadaic Acid	apoptotic process		Okadaic Acid results in increased apoptotic process	1: Chlorocebus aethiops	COS Cells	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
14.	Okadaic Acid	apoptotic process		Okadaic Acid results in increased apoptotic process	1: Homo sapiens	HeLa Cells	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	2
15.	Okadaic Acid	apoptotic process	Ursodeoxycholic Acid	Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process]	1: Homo sapiens	Hepatocytes \| Cell Line, Tumor	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
16.	Okadaic Acid	apoptotic process	Ursodeoxycholic Acid	Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process]	1: Homo sapiens	Bone and Bones \| Cell Line, Tumor	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
17.	Okadaic Acid	apoptotic process	Ursodeoxycholic Acid	Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process]	1: Chlorocebus aethiops	COS Cells	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
18.	Okadaic Acid	apoptotic process	Ursodeoxycholic Acid	Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process]	1: Homo sapiens	HeLa Cells	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
19.	Okadaic Acid	regulation of mitochondrial membrane potential		Okadaic Acid results in decreased regulation of mitochondrial membrane potential	1: Homo sapiens	Bone and Bones \| Cell Line, Tumor	5 genes: BAX \| BCL2 \| SOD1 \| SOD2 \| UCP2	1
20.	Okadaic Acid	regulation of mitochondrial membrane potential	Ursodeoxycholic Acid	Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in decreased regulation of mitochondrial membrane potential]	1: Homo sapiens	Bone and Bones \| Cell Line, Tumor	5 genes: BAX \| BCL2 \| SOD1 \| SOD2 \| UCP2	1
21.	Okadaic Acid	response to oxidative stress		Okadaic Acid results in increased response to oxidative stress	1: Homo sapiens	Bone and Bones \| Cell Line, Tumor	21 genes: ABL1 \| AKT1 \| ALDH1A1 \| APP \| BCL2 \| COX2 \| DDIT3 \| EPAS1 \| JAK2 \| MMP2 \| NFKB1 \| PCNA \| PRDX5 \| PRDX6 \| PTGS2 \| SELENOP \| SOD1 \| SOD2 \| TOR1A \| TP53 \| TRP53	1
22.	Okadaic Acid	response to oxidative stress		Okadaic Acid inhibits the reaction [Okadaic Acid results in increased response to oxidative stress]	1: Homo sapiens	Bone and Bones \| Cell Line, Tumor	21 genes: ABL1 \| AKT1 \| ALDH1A1 \| APP \| BCL2 \| COX2 \| DDIT3 \| EPAS1 \| JAK2 \| MMP2 \| NFKB1 \| PCNA \| PRDX5 \| PRDX6 \| PTGS2 \| SELENOP \| SOD1 \| SOD2 \| TOR1A \| TP53 \| TRP53	1
23.	Okadaic Acid	apoptotic process		Okadaic Acid results in increased apoptotic process	1: Rattus norvegicus	Hepatocytes \| Cells, Cultured	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
24.	Okadaic Acid	apoptotic DNA fragmentation		Okadaic Acid results in increased apoptotic DNA fragmentation	1: Rattus norvegicus	Hepatocytes \| Cells, Cultured	1 gene: CASP3	1
25.	Okadaic Acid	apoptotic DNA fragmentation	Ursodeoxycholic Acid	Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic DNA fragmentation]	1: Rattus norvegicus	Hepatocytes \| Cells, Cultured	1 gene: CASP3	1
26.	Okadaic Acid	regulation of mitochondrial membrane potential		Okadaic Acid results in decreased regulation of mitochondrial membrane potential	1: Rattus norvegicus	Hepatocytes \| Cells, Cultured	5 genes: BAX \| BCL2 \| SOD1 \| SOD2 \| UCP2	1
27.	Okadaic Acid	regulation of mitochondrial membrane potential	Ursodeoxycholic Acid	Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in decreased regulation of mitochondrial membrane potential]	1: Rattus norvegicus	Hepatocytes \| Cells, Cultured	5 genes: BAX \| BCL2 \| SOD1 \| SOD2 \| UCP2	1
28.	Okadaic Acid	apoptotic process	Ursodeoxycholic Acid	Ursodeoxycholic Acid inhibits the reaction [Okadaic Acid results in increased apoptotic process]	1: Rattus norvegicus	Hepatocytes \| Cells, Cultured	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
29.	Okadaic Acid	cell proliferation	Clofibrate	Okadaic Acid inhibits the reaction [Clofibrate results in decreased cell proliferation]	1: Rattus norvegicus	Hepatocytes \| Cell Line, Tumor	18 genes: ADRA1B \| AKT1 \| BAX \| BCL2 \| CDK1 \| CREBBP \| CTNNB1 \| DAB2 \| ELN \| IGF1 \| MAPRE2 \| PCNA \| RAF1 \| SDCBP2 \| TOP2A \| TP53 \| TXN \| VEGFA	1
30.	Okadaic Acid	apoptotic process		Okadaic Acid results in increased apoptotic process		Lymphocytes \| Cell Line	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
31.	Okadaic Acid	apoptotic process	BCL2	[Okadaic Acid results in increased apoptotic process] which results in increased phosphorylation of BCL2 protein		Lymphocytes \| Cell Line	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
32.	Okadaic Acid	response to oxidative stress		Okadaic Acid results in increased response to oxidative stress	1: Homo sapiens	HeLa Cells	21 genes: ABL1 \| AKT1 \| ALDH1A1 \| APP \| BCL2 \| COX2 \| DDIT3 \| EPAS1 \| JAK2 \| MMP2 \| NFKB1 \| PCNA \| PRDX5 \| PRDX6 \| PTGS2 \| SELENOP \| SOD1 \| SOD2 \| TOR1A \| TP53 \| TRP53	1
33.	Okadaic Acid	response to oxidative stress	Glutathione	[Okadaic Acid results in increased response to oxidative stress] which results in decreased abundance of Glutathione	1: Homo sapiens	HeLa Cells	21 genes: ABL1 \| AKT1 \| ALDH1A1 \| APP \| BCL2 \| COX2 \| DDIT3 \| EPAS1 \| JAK2 \| MMP2 \| NFKB1 \| PCNA \| PRDX5 \| PRDX6 \| PTGS2 \| SELENOP \| SOD1 \| SOD2 \| TOR1A \| TP53 \| TRP53	1
34.	Okadaic Acid	apoptotic DNA fragmentation		Okadaic Acid results in increased apoptotic DNA fragmentation	1: Homo sapiens	HeLa Cells	1 gene: CASP3	1
35.	Okadaic Acid	DNA methylation	Ionomycin \| Tetradecanoylphorbol Acetate	Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased DNA methylation]	1: Homo sapiens	Veins \| Blood \| T-Lymphocytes \| Cells, Cultured	2 genes: DNMT1 \| FOS	1
36.	Okadaic Acid	actin filament depolymerization		Okadaic Acid results in increased actin filament depolymerization	1: Homo sapiens	Liver \| Cell Line	2 genes: CFL1 \| DSTN	1
37.	Okadaic Acid	apoptotic process	Benzo(a)pyrene \| Tetrachlorodibenzodioxin	Okadaic Acid inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [Benzo(a)pyrene results in increased apoptotic process]]	1: Homo sapiens	Hep G2 Cells	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
38.	Okadaic Acid	apoptotic process	2,4,5,2',4',5'-hexachlorobiphenyl \| Benzo(a)pyrene	Okadaic Acid inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Benzo(a)pyrene results in increased apoptotic process]]	1: Homo sapiens	Hep G2 Cells	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
39.	Okadaic Acid	apoptotic process	Benzo(a)pyrene \| Estradiol	Okadaic Acid inhibits the reaction [Estradiol inhibits the reaction [Benzo(a)pyrene results in increased apoptotic process]]	1: Homo sapiens	Hep G2 Cells	52 genes: ABL1 \| AKT1 \| APP \| ATP5F1A \| BAX \| BBC3 \| BCL2 \| BCL2L11 \| BCL2L14 \| CASP3 \| CASP7 \| CASP8 \| CASP9 \| CDK1 \| DAB2 \| DDIT3 \| EGLN3 \| EP300 \| ERN1 \| FOXO3 \| GAPDH \| GJA1 \| HTRA2 \| IER3 \| IL1B \| ITPR1 \| JAK2 \| MAP3K10 \| MAPK1 \| MAPK3 \| MAPT \| MFN2 \| NFKB1 \| NFKBIA \| NR3C1 \| OPA1 \| PARP1 \| PPP2CA \| PPP2R1A \| PRDX5 \| RAD21 \| RAF1 \| RB1 \| RPS6KB1 \| TAX1BP1 \| TF \| TNF \| TNFSF10 \| TP53 \| TRP53 \| UBE2D3 \| XBP1	1
40.	Okadaic Acid	positive regulation of NF-kappaB transcription factor activity		Okadaic Acid results in increased positive regulation of NF-kappaB transcription factor activity	1: Homo sapiens	U937 Cells	9 genes: AGT \| APP \| CLU \| IL1B \| IRAK1 \| NFKB1 \| RELA \| TNF \| UBC	1
41.	Okadaic Acid	positive regulation of NF-kappaB transcription factor activity		Okadaic Acid results in increased positive regulation of NF-kappaB transcription factor activity	1: Homo sapiens	MCF-7 Cells	9 genes: AGT \| APP \| CLU \| IL1B \| IRAK1 \| NFKB1 \| RELA \| TNF \| UBC	1
42.	Okadaic Acid	positive regulation of NF-kappaB transcription factor activity	SOD2	SOD2 protein inhibits the reaction [Okadaic Acid results in increased positive regulation of NF-kappaB transcription factor activity]	1: Homo sapiens	MCF-7 Cells	9 genes: AGT \| APP \| CLU \| IL1B \| IRAK1 \| NFKB1 \| RELA \| TNF \| UBC	1
43.	Okadaic Acid	positive regulation of cell death		Okadaic Acid results in increased positive regulation of cell death	1: Homo sapiens	MCF-7 Cells	10 genes: ACOX2 \| BCL2L11 \| EGR1 \| EP300 \| GRIN1 \| HTRA2 \| IL1B \| PDX1 \| PTGS2 \| UCP2	1
44.	Okadaic Acid	positive regulation of cell death	SOD2	SOD2 protein inhibits the reaction [Okadaic Acid results in increased positive regulation of cell death]	1: Homo sapiens	MCF-7 Cells	10 genes: ACOX2 \| BCL2L11 \| EGR1 \| EP300 \| GRIN1 \| HTRA2 \| IL1B \| PDX1 \| PTGS2 \| UCP2	1
45.	Okadaic Acid	regulation of vascular permeability	mustard oil \| sodium arsenite	Okadaic Acid inhibits the reaction [sodium arsenite promotes the reaction [mustard oil affects regulation of vascular permeability]]	1: Mus musculus	Microvessels		1
46.	Okadaic Acid	positive regulation of apoptotic process		Okadaic Acid affects positive regulation of apoptotic process	1: Mus musculus	Brain \| Neurons \| Cells, Cultured	47 genes: ABL1 \| AKT1 \| ALDH1A1 \| ANXA5 \| ARHGEF17 \| BAX \| BBC3 \| BCL2L11 \| CASP3 \| CASP8 \| CASP9 \| CLU \| CREB1 \| CTNNB1 \| CYP1B1 \| DDIT3 \| DNM1L \| EGLN1 \| FOSL1 \| FOXO3 \| GRIN1 \| GSK3B \| HIF1A \| HTRA2 \| IL1B \| ITPR1 \| JAK2 \| JUN \| MAP3K10 \| MAPK8 \| MLLT11 \| MMP2 \| NGF \| PDIA3 \| PLA2G4A \| PPP2CA \| PTGS2 \| PTN \| RELA \| RXRA \| SOD1 \| TNF \| TNFSF10 \| TOP2A \| TP53 \| TRP53 \| UBC	1
47.	Okadaic Acid	positive regulation of apoptotic process	BBC3	BBC3 protein affects the reaction [Okadaic Acid affects positive regulation of apoptotic process]	1: Mus musculus	Brain \| Neurons \| Cells, Cultured	47 genes: ABL1 \| AKT1 \| ALDH1A1 \| ANXA5 \| ARHGEF17 \| BAX \| BBC3 \| BCL2L11 \| CASP3 \| CASP8 \| CASP9 \| CLU \| CREB1 \| CTNNB1 \| CYP1B1 \| DDIT3 \| DNM1L \| EGLN1 \| FOSL1 \| FOXO3 \| GRIN1 \| GSK3B \| HIF1A \| HTRA2 \| IL1B \| ITPR1 \| JAK2 \| JUN \| MAP3K10 \| MAPK8 \| MLLT11 \| MMP2 \| NGF \| PDIA3 \| PLA2G4A \| PPP2CA \| PTGS2 \| PTN \| RELA \| RXRA \| SOD1 \| TNF \| TNFSF10 \| TOP2A \| TP53 \| TRP53 \| UBC	1
48.	Okadaic Acid	positive regulation of apoptotic process	TRP53	TRP53 protein affects the reaction [Okadaic Acid affects positive regulation of apoptotic process]	1: Mus musculus	Brain \| Neurons \| Cells, Cultured	47 genes: ABL1 \| AKT1 \| ALDH1A1 \| ANXA5 \| ARHGEF17 \| BAX \| BBC3 \| BCL2L11 \| CASP3 \| CASP8 \| CASP9 \| CLU \| CREB1 \| CTNNB1 \| CYP1B1 \| DDIT3 \| DNM1L \| EGLN1 \| FOSL1 \| FOXO3 \| GRIN1 \| GSK3B \| HIF1A \| HTRA2 \| IL1B \| ITPR1 \| JAK2 \| JUN \| MAP3K10 \| MAPK8 \| MLLT11 \| MMP2 \| NGF \| PDIA3 \| PLA2G4A \| PPP2CA \| PTGS2 \| PTN \| RELA \| RXRA \| SOD1 \| TNF \| TNFSF10 \| TOP2A \| TP53 \| TRP53 \| UBC	1
49.	Okadaic Acid	protein serine/threonine phosphatase activity	SLCO1B1	[SLCO1B1 protein results in increased susceptibility to Okadaic Acid] which results in decreased protein serine/threonine phosphatase activity	1: Homo sapiens	HEK293 Cells	5 genes: PPP1CA \| PPP2CA \| PPP2R1A \| PPP4C \| PPP5C	1
50.	Okadaic Acid	protein serine/threonine phosphatase activity	SLCO1B3	[SLCO1B3 protein results in increased susceptibility to Okadaic Acid] which results in decreased protein serine/threonine phosphatase activity	1: Homo sapiens	HEK293 Cells	5 genes: PPP1CA \| PPP2CA \| PPP2R1A \| PPP4C \| PPP5C	1

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