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Chemical Endothelin-1

Name Endothelin-1
Equivalent Terms Big Endothelin | Big Endothelin 1 | Big Endothelin-1 | Endothelin 1 | Endothelin-1, Big | Endothelin, Big | Endothelin Type 1 | Precursor, Proendothelin-1 | Preproendothelin | Preproendothelin 1 | Preproendothelin-1 | Proendothelin (1-38) | Proendothelin 1 Precursor | Proendothelin-1 Precursor
Definition A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D019332
External Links

Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Endothelins Has associated genes Has associated diseases Endothelin-1

Top ↑ Descendants

  Alexa532-endothelin 1
  C-terminal proendothelin-1
  edn1 protein, zebrafish
  endothelin-1 (1-21)
  endothelin-1 (1-21), (Cys,Acm(1,15),Aib(3,11),Leu(7))-
  endothelin-1 (1-31)
  endothelin-1, Aba(1,15)-
  endothelin-1, (Aib(1,3,11,15),Nle(7))-
  endothelin-1, Ala(10)-
  endothelin-1, Cys(Acm)(1,15)-Ala(3)-Leu(7)-Aib(11)-
  endothelin-1, formylTrp(21)-
  endothelin-1, lysyl(-2)-arginyl(-1)-
  endothelin-1, Pen(1,11)-Nle(7)-Ala(18)-
  endothelin-1, Pen(1,11)-Nle(7)-Asn(18)-
  endothelin-1, Phe(16)-
  endothelin-1, Thr(18)-Cha(19)-
  endothelin-1, Thr(18)-Leu(19)-
  proendothelin 1