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Chemical 2,3-Diphosphoglycerate

Name 2,3-Diphosphoglycerate
Equivalent Terms 2,3-Bisphosphate, Glycerate | 2,3 Bisphosphoglycerate | 2,3-Bisphosphoglycerate | 2,3 Diphosphoglycerate | 2,3-Diphosphoglycerate, (D)-Isomer | 2,3 Diphosphoglyceric Acid | 2,3-Diphosphoglyceric Acid | 2,3-DPG | Glycerate 2,3-Bisphosphate
CAS Registry Number 138-81-8
Definition A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
Structure 2,3-Diphosphoglycerate
Curator Note For additional curated data about phosphorus, please also see Phosphorus and its chemical descendants.
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Genes
MeSH® ID D019794
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Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Carboxylic Acids Has associated genes Has associated diseases Has associated exposure references Acids, Acyclic Has associated genes Has associated diseases Has associated exposure references Sugar Acids Has associated genes Has associated diseases Has associated exposure references Glyceric Acids Has associated genes Has associated diseases Diphosphoglyceric Acids Has associated genes Has associated diseases 2,3-Diphosphoglycerate Has associated genes Has associated diseases
2. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Carboxylic Acids Has associated genes Has associated diseases Has associated exposure references Hydroxy Acids Has associated genes Has associated diseases Has associated exposure references Sugar Acids Has associated genes Has associated diseases Has associated exposure references Glyceric Acids Has associated genes Has associated diseases Diphosphoglyceric Acids Has associated genes Has associated diseases 2,3-Diphosphoglycerate Has associated genes Has associated diseases
3. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Organophosphorus Compounds Has associated genes Has associated diseases Has associated exposure references Organophosphates Has associated genes Has associated diseases Has associated exposure references Diphosphoglyceric Acids Has associated genes Has associated diseases 2,3-Diphosphoglycerate Has associated genes Has associated diseases
4. ChemicalsCarbohydrates Has associated genes Has associated diseases Has associated exposure references Sugar Acids Has associated genes Has associated diseases Has associated exposure references Glyceric Acids Has associated genes Has associated diseases Diphosphoglyceric Acids Has associated genes Has associated diseases 2,3-Diphosphoglycerate Has associated genes Has associated diseases

Top ↑ Descendants

2,3-Diphosphoglycerate Has associated genes Has associated diseases
  cyclic-2,3-diphosphoglycerate
  deoxyhaemoglobin-2,3-diphosphoglycerate complex