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Chemical Selective Estrogen Receptor Modulators

Name Selective Estrogen Receptor Modulators
Equivalent Terms Estrogen Receptor Modulator, Selective | Estrogen Receptor Modulators, Selective | Selective Estrogen Receptor Modulator | SERM | SERMs
Definition A structurally diverse group of compounds distinguished from ESTROGENS by their ability to bind and activate ESTROGEN RECEPTORS but act as either an agonist or antagonist depending on the tissue type and hormonal milieu. They are classified as either first generation because they demonstrate estrogen agonist properties in the ENDOMETRIUM or second generation based on their patterns of tissue specificity. (Horm Res 1997;48:155-63)
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Genes
MeSH® ID D020845
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1. ChemicalsHormones, Hormone Substitutes, and Hormone Antagonists Has associated genes Has associated diseases Has associated exposure references Hormone Antagonists Has associated genes Has associated diseases Estrogen Receptor Modulators Has associated genes Has associated diseases Selective Estrogen Receptor Modulators Has associated genes Has associated diseases
2. ChemicalsChemical Actions and Uses Has associated genes Has associated diseases Has associated exposure references Pharmacologic Actions Has associated genes Has associated diseases Has associated exposure references Physiological Effects of Drugs Has associated genes Has associated diseases Has associated exposure references Hormones, Hormone Substitutes, and Hormone Antagonists Has associated genes Has associated diseases Has associated exposure references Hormone Antagonists Has associated genes Has associated diseases Estrogen Receptor Modulators Has associated genes Has associated diseases Selective Estrogen Receptor Modulators Has associated genes Has associated diseases

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