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Chemical Indole Alkaloids

1–50 of 845 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 7-hydroxymitragynine small intestine smooth muscle contraction 7-hydroxymitragynine affects small intestine smooth muscle contraction 1: Cavia porcellus Ileum   1
2. 7-hydroxymitragynine smooth muscle contraction 7-hydroxymitragynine affects smooth muscle contraction 1: Mus musculus Vas Deferens   1
3. 7-hydroxystaurosporine cell proliferation 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide [7-hydroxystaurosporine co-treated with 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide] results in decreased cell proliferation 1: Homo sapiens Cells
9 genes: BCL2 | BCL2L1 | CDC25C | CDK1 | CDK4 | MAP2K1 | MKI67 | RAF1 | TP53
1
4. 7-hydroxystaurosporine cell death Cisplatin 7-hydroxystaurosporine promotes the reaction [Cisplatin results in increased cell death]     1
5. 7-hydroxystaurosporine apoptotic process Sirolimus [7-hydroxystaurosporine co-treated with Sirolimus] results in increased apoptotic process 1: Homo sapiens Jurkat Cells
26 genes: AIFM1 | BAG1 | BCL2 | BCL2L1 | BID | BIRC5 | CASP2 | CASP3 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | DIABLO | E2F1 | LCK | MAPK1 | MAPK3 | MCL1 | PARP1 | PRKCA | RAF1 | RB1 | RPS6KA3 | TP53 | XIAP
1
6. 7-hydroxystaurosporine apoptotic process Boc-D-FMK | Sirolimus Boc-D-FMK inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased apoptotic process] 1: Homo sapiens U937 Cells
26 genes: AIFM1 | BAG1 | BCL2 | BCL2L1 | BID | BIRC5 | CASP2 | CASP3 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | DIABLO | E2F1 | LCK | MAPK1 | MAPK3 | MCL1 | PARP1 | PRKCA | RAF1 | RB1 | RPS6KA3 | TP53 | XIAP
1
7. 7-hydroxystaurosporine cell cycle Sirolimus [7-hydroxystaurosporine co-treated with Sirolimus] results in decreased cell cycle 1: Homo sapiens B-Lymphocytes | Cell Line, Tumor
15 genes: BIRC5 | CCND1 | CDC25C | CDK1 | CDK4 | CDK6 | CHEK1 | CHEK2 | E2F1 | MAPK1 | MAPK3 | MKI67 | RB1 | RPS6KA3 | TP53
1
8. 7-hydroxystaurosporine regulation of mitochondrial membrane potential Sirolimus [7-hydroxystaurosporine co-treated with Sirolimus] results in decreased regulation of mitochondrial membrane potential 1: Homo sapiens U937 Cells
2 genes: BCL2 | BCL2L1
1
9. 7-hydroxystaurosporine apoptotic DNA fragmentation 7-hydroxystaurosporine results in increased apoptotic DNA fragmentation 1: Homo sapiens B-Lymphocytes | Tumor Cells, Cultured 1 gene: CASP3 1
10. 7-hydroxystaurosporine apoptotic process pyrazolanthrone | Sirolimus pyrazolanthrone inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in increased apoptotic process] 1: Homo sapiens U937 Cells
26 genes: AIFM1 | BAG1 | BCL2 | BCL2L1 | BID | BIRC5 | CASP2 | CASP3 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | DIABLO | E2F1 | LCK | MAPK1 | MAPK3 | MCL1 | PARP1 | PRKCA | RAF1 | RB1 | RPS6KA3 | TP53 | XIAP
1
11. 7-hydroxystaurosporine regulation of mitochondrial membrane potential pyrazolanthrone | Sirolimus pyrazolanthrone inhibits the reaction [[Sirolimus co-treated with 7-hydroxystaurosporine] results in decreased regulation of mitochondrial membrane potential] 1: Homo sapiens U937 Cells
2 genes: BCL2 | BCL2L1
1
12. 7-hydroxystaurosporine apoptotic process Sirolimus [7-hydroxystaurosporine co-treated with Sirolimus] results in increased apoptotic process 1: Homo sapiens B-Lymphocytes | Cell Line, Tumor
26 genes: AIFM1 | BAG1 | BCL2 | BCL2L1 | BID | BIRC5 | CASP2 | CASP3 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | DIABLO | E2F1 | LCK | MAPK1 | MAPK3 | MCL1 | PARP1 | PRKCA | RAF1 | RB1 | RPS6KA3 | TP53 | XIAP
2
13. 7-hydroxystaurosporine positive regulation of apoptotic process Methotrexate [Methotrexate co-treated with 7-hydroxystaurosporine] results in increased positive regulation of apoptotic process 1: Mus musculus Melanocytes | Cell Line, Tumor
12 genes: AIFM1 | BCL2L1 | BID | CASP2 | CASP3 | CASP8 | CASP9 | CDK4 | DIABLO | E2F1 | MAPK8 | TP53
1
14. 7-hydroxystaurosporine mitotic G2 DNA damage checkpoint erythritol anhydride 7-hydroxystaurosporine inhibits the reaction [erythritol anhydride results in increased mitotic G2 DNA damage checkpoint] 1: Mus musculus Spermatocytes | Cell Line
2 genes: CDK1 | CHEK1
1
15. 7-hydroxystaurosporine cell cycle Cisplatin | Nocodazole Nocodazole inhibits the reaction [7-hydroxystaurosporine inhibits the reaction [Cisplatin results in decreased cell cycle]] 1: Homo sapiens Breast | Cell Line, Tumor
15 genes: BIRC5 | CCND1 | CDC25C | CDK1 | CDK4 | CDK6 | CHEK1 | CHEK2 | E2F1 | MAPK1 | MAPK3 | MKI67 | RB1 | RPS6KA3 | TP53
1
16. 7-hydroxystaurosporine cell death 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide promotes the reaction [7-hydroxystaurosporine results in increased cell death] 1: Homo sapiens Breast | Cell Line, Tumor   1
17. 7-hydroxystaurosporine cell proliferation Sirolimus [7-hydroxystaurosporine co-treated with Sirolimus] results in decreased cell proliferation 1: Homo sapiens B-Lymphocytes | Cell Line, Tumor
9 genes: BCL2 | BCL2L1 | CDC25C | CDK1 | CDK4 | MAP2K1 | MKI67 | RAF1 | TP53
1
18. 7-hydroxystaurosporine cell death 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide 7-hydroxystaurosporine promotes the reaction [2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide results in increased cell death] 1: Homo sapiens Breast | Cell Line, Tumor   1
19. 7-hydroxystaurosporine apoptotic process Sirolimus [7-hydroxystaurosporine co-treated with Sirolimus] results in increased apoptotic process 1: Homo sapiens U937 Cells
26 genes: AIFM1 | BAG1 | BCL2 | BCL2L1 | BID | BIRC5 | CASP2 | CASP3 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | DIABLO | E2F1 | LCK | MAPK1 | MAPK3 | MCL1 | PARP1 | PRKCA | RAF1 | RB1 | RPS6KA3 | TP53 | XIAP
1
20. 7-hydroxystaurosporine apoptotic process Cisplatin [Cisplatin co-treated with 7-hydroxystaurosporine] results in increased apoptotic process 1: Homo sapiens Breast | Cell Line, Tumor
26 genes: AIFM1 | BAG1 | BCL2 | BCL2L1 | BID | BIRC5 | CASP2 | CASP3 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | DIABLO | E2F1 | LCK | MAPK1 | MAPK3 | MCL1 | PARP1 | PRKCA | RAF1 | RB1 | RPS6KA3 | TP53 | XIAP
1
21. 7-hydroxystaurosporine cell cycle Cisplatin 7-hydroxystaurosporine inhibits the reaction [Cisplatin results in decreased cell cycle] 1: Homo sapiens Breast | Cell Line, Tumor
15 genes: BIRC5 | CCND1 | CDC25C | CDK1 | CDK4 | CDK6 | CHEK1 | CHEK2 | E2F1 | MAPK1 | MAPK3 | MKI67 | RB1 | RPS6KA3 | TP53
1
22. 7-hydroxystaurosporine cell death 7-hydroxystaurosporine results in increased cell death 1: Homo sapiens Breast | Cell Line, Tumor   1
23. 7-hydroxystaurosporine apoptotic process Cisplatin | Nocodazole Nocodazole inhibits the reaction [[Cisplatin co-treated with 7-hydroxystaurosporine] results in increased apoptotic process] 1: Homo sapiens Breast | Cell Line, Tumor
26 genes: AIFM1 | BAG1 | BCL2 | BCL2L1 | BID | BIRC5 | CASP2 | CASP3 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | DIABLO | E2F1 | LCK | MAPK1 | MAPK3 | MCL1 | PARP1 | PRKCA | RAF1 | RB1 | RPS6KA3 | TP53 | XIAP
1
24. 7-hydroxystaurosporine apoptotic process 7-hydroxystaurosporine results in increased apoptotic process 1: Homo sapiens B-Lymphocytes | Tumor Cells, Cultured
26 genes: AIFM1 | BAG1 | BCL2 | BCL2L1 | BID | BIRC5 | CASP2 | CASP3 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | DIABLO | E2F1 | LCK | MAPK1 | MAPK3 | MCL1 | PARP1 | PRKCA | RAF1 | RB1 | RPS6KA3 | TP53 | XIAP
1
25. 7-hydroxystaurosporine cell death 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide [7-hydroxystaurosporine co-treated with 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide] results in increased cell death 1: Homo sapiens Cells   1
26. 9-hydroxycanthin-6-one apoptotic process 9-hydroxycanthin-6-one results in increased apoptotic process 1: Homo sapiens Ovary | Tumor Cells, Cultured
3 genes: CASP3 | CASP8 | CASP9
1
27. 9-hydroxycanthin-6-one cell death benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [9-hydroxycanthin-6-one results in increased cell death] 1: Homo sapiens Ovary | Tumor Cells, Cultured   1
28. 9-hydroxycanthin-6-one cell death Acetylcysteine Acetylcysteine inhibits the reaction [9-hydroxycanthin-6-one results in increased cell death] 1: Homo sapiens Ovary | Tumor Cells, Cultured   1
29. 9-hydroxycanthin-6-one reactive oxygen species biosynthetic process 9-hydroxycanthin-6-one results in increased reactive oxygen species biosynthetic process 1: Homo sapiens Ovary | Tumor Cells, Cultured   1
30. 9-hydroxycanthin-6-one cell proliferation 9-hydroxycanthin-6-one results in decreased cell proliferation 1: Homo sapiens Ovary | Tumor Cells, Cultured   1
31. 9-hydroxycanthin-6-one cell death benzyloxycarbonyl-valyl-alanyl-aspartic acid benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [9-hydroxycanthin-6-one results in increased cell death] 1: Homo sapiens Ovary | Tumor Cells, Cultured   1
32. 9-hydroxycanthin-6-one cell death 9-hydroxycanthin-6-one results in increased cell death 1: Homo sapiens Ovary | Tumor Cells, Cultured   1
33. 9-methoxy-N(2)-methylellipticinium positive regulation of cell death Phenobarbital Phenobarbital promotes the reaction [9-methoxy-N(2)-methylellipticinium results in increased positive regulation of cell death] 1: Rattus norvegicus Brain   1
34. 9-methoxy-N(2)-methylellipticinium positive regulation of cell death Metyrapone Metyrapone inhibits the reaction [9-methoxy-N(2)-methylellipticinium results in increased positive regulation of cell death] 1: Rattus norvegicus Brain   1
35. 9-methoxy-N(2)-methylellipticinium positive regulation of cell death Dopamine Uptake Inhibitors Dopamine Uptake Inhibitors inhibits the reaction [9-methoxy-N(2)-methylellipticinium results in increased positive regulation of cell death] 1: Rattus norvegicus Brain   1
36. 9-methoxy-N(2)-methylellipticinium positive regulation of cell death 9-methoxy-N(2)-methylellipticinium results in increased positive regulation of cell death 1: Rattus norvegicus Brain   1
37. 9-methoxy-N(2)-methylellipticinium positive regulation of cell death Serotonin Uptake Inhibitors Serotonin Uptake Inhibitors inhibits the reaction [9-methoxy-N(2)-methylellipticinium results in increased positive regulation of cell death] 1: Rattus norvegicus Brain   1
38. 9-methoxy-N(2)-methylellipticinium positive regulation of cell death Reserpine Reserpine inhibits the reaction [9-methoxy-N(2)-methylellipticinium results in increased positive regulation of cell death] 1: Rattus norvegicus Brain   1
39. 9-methoxy-N(2)-methylellipticinium positive regulation of cell death Piperonyl Butoxide Piperonyl Butoxide inhibits the reaction [9-methoxy-N(2)-methylellipticinium results in increased positive regulation of cell death] 1: Rattus norvegicus Brain   1
40. Ajmaline glycolytic process Ajmaline results in increased glycolytic process 1: Oryctolagus cuniculus Heart   1
41. Ajmaline regulation of heart rate Ajmaline results in decreased regulation of heart rate 1: Rattus norvegicus Cardiovascular System 1 gene: SCN5A 1
42. Ajmaline regulation of heart rate Ajmaline results in decreased regulation of heart rate 1: Homo sapiens Heart 1 gene: SCN5A 1
43. brucine cell death Antimycin A brucine inhibits the reaction [Antimycin A results in increased cell death] Kidney Tubules, Proximal 1 gene: CTSD 1
44. brucine apoptotic process Diethylnitrosamine [Diethylnitrosamine co-treated with brucine] results in increased apoptotic process 1: Rattus norvegicus  
5 genes: BAX | BCL2 | CASP3 | CASP9 | TNF
1
45. brucine negative regulation of cellular response to hypoxia brucine affects negative regulation of cellular response to hypoxia 1: Mus musculus     1
46. brucine negative regulation of cellular response to hypoxia brucine affects negative regulation of cellular response to hypoxia 1: Homo sapiens Hep G2 Cells   1
47. brucine negative regulation of cell migration brucine affects negative regulation of cell migration 1: Homo sapiens Liver | Tumor Cells, Cultured 1 gene: BCL2 1
48. brucine negative regulation of cell migration brucine affects negative regulation of cell migration 1: Homo sapiens Hep G2 Cells 1 gene: BCL2 1
49. brucine angiogenesis Diethylnitrosamine brucine inhibits the reaction [Diethylnitrosamine results in increased angiogenesis] 1: Rattus norvegicus  
3 genes: FN1 | MMP2 | PTGS2
1
50. debromoaplysiatoxin apoptotic process Fenretinide debromoaplysiatoxin inhibits the reaction [Fenretinide results in increased apoptotic process] 1: Homo sapiens Cell Line, Tumor   1
1–50 of 845 results.