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Chemical Low Density Lipoprotein Receptor-Related Protein-2

Name Low Density Lipoprotein Receptor-Related Protein-2
Equivalent Terms Antigen GP 330, Nephritis | Glycoprotein 330 | Glycoprotein GP330, Renal | GP330 Antigen | GP330, Renal Glycoprotein | Heymann Nephritis Antigen GP330 | Heyman's Nephritis Antigen GP330 | LDL Receptor Related Protein 2 | LDL-Receptor Related Protein 2 | Low Density Lipoprotein Receptor Related Protein 2 | Low-Density Lipoprotein Receptor-Related Protein-2 | LRP 2 Receptor | LRP-2 Receptor | Megalin | Nephritis Antigen (GP330) | Renal Glycoprotein GP330
Definition An LDL-RECEPTOR RELATED PROTEIN found in the neuroepithelium and in proximal tubular cells of the kidney. It is considered a multiligand receptor in that it binds to a variety of ligands with relatively high affinity and may function in mediating the uptake and lysosomal degradation of macromolecules such as: LIPOPROTEINS; ENDOPEPTIDASES; and PROTEASE INHIBITORS.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D026561
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Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Antigens Has associated genes Has associated diseases Has associated exposure references Autoantigens Has associated genes Has associated diseases Heymann Nephritis Antigenic Complex Has associated genes Has associated diseases Low Density Lipoprotein Receptor-Related Protein-2

Top ↑ Descendants

Low Density Lipoprotein Receptor-Related Protein-2
  LRP2 protein, human
  Lrp2 protein, mouse
  megalinbinding protein, human
  megalinbinding protein, mouse