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Chemical Isoprostanes

Name Isoprostanes
Equivalent Term Isoprostane
Definition A series of prostaglandin-like compounds that are produced by the attack of free-radical species on unsaturated fatty acids, especially ARACHIDONIC ACID, of cellular MEMBRANES. Once cleaved from the lipid membrane by the action of phospholipases they can circulate into various bodily fluids and eventually be excreted. Although these compounds resemble enzymatically synthesized prostaglandins their stereoisometric arrangement is usually different than the 'naturally occurring' compounds.
Top Interacting
Genes
MeSH® ID D028421
External Links

Top ↑ Ancestors

1. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Unsaturated Has associated genes Has associated diseases Has associated exposure references Eicosanoids Has associated genes Has associated diseases Has associated exposure references Arachidonic Acids Has associated genes Has associated diseases Has associated exposure references Isoprostanes Has associated genes Has associated diseases Has associated exposure references
2. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Unsaturated Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Essential Has associated genes Has associated diseases Has associated exposure references Arachidonic Acids Has associated genes Has associated diseases Has associated exposure references Isoprostanes Has associated genes Has associated diseases Has associated exposure references
3. ChemicalsLipids Has associated genes Has associated diseases Has associated exposure references Fatty Acids Has associated genes Has associated diseases Has associated exposure references Fatty Acids, Unsaturated Has associated genes Has associated diseases Has associated exposure references Isoprostanes Has associated genes Has associated diseases Has associated exposure references

Top ↑ Descendants

Isoprostanes Has associated genes Has associated diseases Has associated exposure references
  15-F2alpha-isoprostane
  15-F2t-isoprostane
  1-palmitoyl-2-(epoxyisoprostane-E2)-sn-glycero-3-phosphocholine Has associated genes Has associated diseases
  4-(3-((3-hydroxy-2-(oct-2-enyl)-5-oxocyclopentylidene)methyl)oxiran-2-yl)butanoic acid
  5,6-epoxyisoprostane E2
  8,12-iso-iPF3alpha-VI
  8-isoprostaglandin A1
  8-isoprostaglandin E2 Has associated genes Has associated diseases
  8-isoprostaglandin F1alpha Has associated exposure references
  A(2) isoprostane
  epoxyisoprostane EC
  epoxyisoprostane EI
View node F2-Isoprostanes Has associated genes Has associated diseases
  isoprostane F2alpha III Has associated diseases
  Neuroprostanes