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Chemical Epothilones

Name Epothilones
Equivalent Terms Epothilon | Epothilone
Definition A group of 16-member MACROLIDES which stabilize MICROTUBULES in a manner similar to PACLITAXEL. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (MYXOCOCCALES).
Top Interacting
Genes
MeSH® ID D034261
External Links

Top ↑ Ancestors

ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Lactones Has associated genes Has associated diseases Has associated exposure references Polyketides Has associated genes Has associated diseases Has associated exposure references Macrolides Has associated genes Has associated diseases Has associated exposure references Epothilones Has associated genes Has associated diseases

Top ↑ Descendants

Epothilones Has associated genes Has associated diseases
  10,11-didehydroepothilone D
  10,14-dihydroxy-9,11,13,13-tetramethyl-2-(1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl)-5-(7-nitro-benzo(1,2,5)oxadiazol-4-yl)-1-oxa-5-aza-cyclohexadecane-12,16-dione
  12,13-cyclopropyl-epothilone B
  12,13-desoxyepothilone F
  15-aza-12,13-desoxyepothilone B
  26-trifluoro-(E)-9,10-dehydro-12,13-desoxyepothilone B
  9,10-dehydroepothilone D
  AV-EPO-106
  BMS 310705 Has associated genes Has associated diseases
  BMS-748285
  BMS-753493
  C12,13-cyclopropylepothilone A
  C26-hydroxyepothilone D
  cryptothilone 1
  desoxyepothilone A
  desoxyepothilone B
  epothilone 490
  epothilone A Has associated diseases
  epothilone B Has associated diseases
  epothilone C
  epothilone E
  epothilone F
  epothilone I
  epothilone K
  fludelone
  ixabepilone Has associated diseases
  KOS-1584
  (S)-14-methoxyepothilone
  sagopilone