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Chemical Aristolochic Acids

Name Aristolochic Acids
Definition Nitro-phenanthrenes occurring in ARISTOLOCHIACEAE and other plants. They derive from stephanine (APORPHINES) by oxidative ring cleavage. The nitro group is a reactive alkylator (ALKYLATING AGENTS) that binds to biological macromolecules. Ingestion by humans is associated with nephropathy (NEPHRITIS). There is no relationship to the similar named aristolochene (SESQUITERPENES).
Top Interacting
Genes
MeSH® ID D034341
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Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Hydrocarbons Has associated genes Has associated diseases Has associated exposure references Hydrocarbons, Cyclic Has associated genes Has associated diseases Has associated exposure references Hydrocarbons, Aromatic Has associated genes Has associated diseases Has associated exposure references Polycyclic Aromatic Hydrocarbons Has associated genes Has associated diseases Has associated exposure references Phenanthrenes Has associated genes Has associated diseases Has associated exposure references Aristolochic Acids Has associated genes Has associated diseases Has associated exposure references
2. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Nitro Compounds Has associated genes Has associated diseases Has associated exposure references Aristolochic Acids Has associated genes Has associated diseases Has associated exposure references
3. ChemicalsPolycyclic Compounds Has associated genes Has associated diseases Has associated exposure references Polycyclic Aromatic Hydrocarbons Has associated genes Has associated diseases Has associated exposure references Phenanthrenes Has associated genes Has associated diseases Has associated exposure references Aristolochic Acids Has associated genes Has associated diseases Has associated exposure references

Top ↑ Descendants

Aristolochic Acids Has associated genes Has associated diseases Has associated exposure references
  3,5-dihydroxy-2,4-dimethoxyaristolactam
  4-demethoxyaristolochic acid BII
  6-methoxyl aristolactam I N-beta-glucoside
  7-(deoxyadenosin-N(6)-yl)aristolactam I Has associated genes Has associated diseases
  7-(deoxyadenosin-N(6)--yl)aristolactam II Has associated genes Has associated diseases
  7-(deoxyguanosin-N(2)-yl)aristolactam I Has associated genes Has associated diseases
  7-(deoxyguanosin-N(2)--yl)aristolactam II
  7-methoxyaristolochic acid A
  7-methoxyaristololactam IV
  9-ethoxyaristolactone
  9-ethoxyaristololactam
  9-hydroxy aristolochic acid I
  aristolactam I Has associated genes Has associated diseases
  aristolic acid
  aristolochic acid B
  aristolochic acid C
  aristolochic acid E
  aristolochic acid F
  aristolochic acid G
  aristolochic acid I Has associated genes Has associated diseases Has associated exposure references
  aristolochic acid II Has associated genes Has associated diseases
  aristololactam A II
  aristololactam BII
  aristololactam-glucoside
  aristololactam-I
  aristololactam IVa
  aristoloside
  cepharanone
  methyl aristolate
  N-((6'-p-coumaroyl)glucopyranosyl)aristolactam
  pressalanine A
  pressalanine B