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Chemical Histamine H1 Antagonists, Non-Sedating

Name Histamine H1 Antagonists, Non-Sedating
Equivalent Terms Antihistamines, Second Generation | H1 Antihistamines, Non Sedating | H1 Antihistamines, Non-Sedating | Histamine H1 Antagonists, Non Sedating | Non-Sedating H1 Antihistamines | Second Generation Antihistamines | Second Generation H1 Antagonists | Third Generation H1 Antagonists
Definition A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment.
Curation Status No gene interactions have been curated for this chemical yet.
MeSH® ID D039563
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1. ChemicalsChemical Actions and Uses Has associated genes Has associated diseases Has associated exposure references Pharmacologic Actions Has associated genes Has associated diseases Has associated exposure references Molecular Mechanisms of Pharmacological Action Has associated genes Has associated diseases Has associated exposure references Neurotransmitter Agents Has associated genes Has associated diseases Has associated exposure references Histamine Agents Has associated diseases Histamine Antagonists Has associated diseases Histamine H1 Antagonists Has associated diseases Histamine H1 Antagonists, Non-Sedating Has associated diseases
2. ChemicalsChemical Actions and Uses Has associated genes Has associated diseases Has associated exposure references Pharmacologic Actions Has associated genes Has associated diseases Has associated exposure references Physiological Effects of Drugs Has associated genes Has associated diseases Has associated exposure references Neurotransmitter Agents Has associated genes Has associated diseases Has associated exposure references Histamine Agents Has associated diseases Histamine Antagonists Has associated diseases Histamine H1 Antagonists Has associated diseases Histamine H1 Antagonists, Non-Sedating Has associated diseases

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