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Chemical Calgranulin A

Name Calgranulin A
Equivalent Terms 60B8 B Antigen | 60B8-B Antigen | A8 Protein, S100 | Antigen, 60B8-B | Antigen, Cystic Fibrosis | CABP-P8 | Cystic Fibrosis Antigen | Leukocyte L1 Protein Light Chain | Macrophage Related Protein 8 | Macrophage-Related Protein-8 | MRP 8 Protein | MRP-8 Protein | MRP8 Protein | Myeloid Calcium Binding Protein P8 | Myeloid Calcium-Binding Protein P8 | S100 A8 Protein | S100A8 Protein
Definition A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D040501
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Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Antigens Has associated genes Has associated diseases Has associated exposure references Antigens, Surface Has associated genes Has associated diseases Leukocyte L1 Antigen Complex Calgranulin A

Top ↑ Descendants

Calgranulin A
  cystic fibrosis serum factor
  S100a8 protein, mouse