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Chemical Vascular Endothelial Growth Factor A

Name Vascular Endothelial Growth Factor A
Equivalent Terms GD-VEGF | Glioma Derived Vascular Endothelial Cell Growth Factor | Glioma-Derived Vascular Endothelial Cell Growth Factor | Permeability Factor, Vascular | Vascular Endothelial Growth Factor | Vascular Endothelial Growth Factor-A | Vascular Permeability Factor | Vasculotropin | VEGF | VEGF-A
Definition The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as 'tumor angiogenesis factor' and 'vascular permeability factor'. Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D042461
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Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Angiogenic Proteins Has associated genes Has associated diseases Vascular Endothelial Growth Factors Has associated genes Has associated diseases Vascular Endothelial Growth Factor A

Top ↑ Descendants

Vascular Endothelial Growth Factor A
  64Cu-DOTA-VEGF(DEE)
  human vascular endothelial growth factor-staphylococcal enterotoxin A fusion protein
  technetium 99m HYNIC-vascular endothelial growth factor
  vammin protein, Vipera ammodytes ammodytes
  vascular endothelial growth factor A (138-165)
  vascular endothelial growth factor A, mouse
  vascular endothelial growth factor A, rat
  VEGFA protein, human
  VEGF protein, zebrafish