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Chemical 4-Quinolones

Name 4-Quinolones
Equivalent Terms 4 Oxoquinolines | 4-Oxoquinolines | 4 Quinolinones | 4-Quinolinones | 4 Quinolones
Definition QUINOLONES containing a 4-oxo (a carbonyl in the para position to the nitrogen). They inhibit the A subunit of DNA GYRASE and are used as antimicrobials. Second generation 4-quinolones are also substituted with a 1-piperazinyl group at the 7-position and a fluorine at the 6-position.
Top Interacting
Genes
MeSH® ID D042462
External Links

Top ↑ Ancestors

ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated exposure references Quinolines Has associated genes Has associated diseases Has associated exposure references Quinolones Has associated genes Has associated diseases 4-Quinolones Has associated genes Has associated diseases

Top ↑ Descendants

4-Quinolones Has associated genes Has associated diseases
  1-tert-butyl-7-tert-butylamino-6-nitro-1,4-dihydro-4-quinolone-3-carboxylic acid
  2-heptyl-4-quinolone
  2-methyl-3-phenylaminomethylquinolin-4-one
  4-quinolone-3-carboxylic acid
  (6-bromo-1-(4-fluorophenylmethyl)-4(1H)-quinolinon-3-yl)-4-hydroxy-2-oxo-3-butenoic acid
  KSI-3716
View node Nalidixic Acid Has associated genes Has associated diseases
  Nedocromil Has associated genes Has associated diseases
View node Oxolinic Acid Has associated diseases
  pyrrolo(3,2-c)quinolin-4-one
  rosoxacin N-oxide
  waltherione C