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Chemical Angiopoietin-2

Name Angiopoietin-2
Equivalent Term Angiopoietin 2
Definition An angiopoietin that is closely related to ANGIOPOIETIN-1. It binds to the TIE-2 RECEPTOR without receptor stimulation and antagonizes the effect of ANGIOPOIETIN-1. However its antagonistic effect may be limited to cell receptors that occur within the vasculature. Angiopoietin-2 may therefore play a role in down-regulation of BLOOD VESSEL branching and sprouting.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D042702
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Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Angiogenic Proteins Has associated genes Has associated diseases Angiopoietins Angiopoietin-2

Top ↑ Descendants

Angiopoietin-2
  ANGPT2 protein, human