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Chemical Tetrahydroisoquinolines

Name Tetrahydroisoquinolines
CAS Type 1 Name Isoquinolines, 1,2,3,4-tetrahydro-
Equivalent Terms 1,2,3,4-Tetrahydroisoquinolines | Tetrahydro Isoquinolines | Tetrahydro-Isoquinolines
Definition A group of ISOQUINOLINES in which the nitrogen containing ring is protonated. They derive from the non-enzymatic Pictet-Spengler condensation of CATECHOLAMINES with ALDEHYDES.
Top Interacting
Genes
MeSH® ID D044005
External Links

Top ↑ Ancestors

ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, Fused-Ring Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 2-Ring Has associated genes Has associated diseases Has associated exposure references Isoquinolines Has associated genes Has associated diseases Tetrahydroisoquinolines Has associated genes Has associated diseases

Top ↑ Descendants

Tetrahydroisoquinolines Has associated genes Has associated diseases
  10-O-demethylcephaeline
  1-(1-adamantyl)-2-(4-(2-chloropyrimidinyl))-1,2,3,4-tetrahydroisoquinoline
  1,1-dimethyl-6-methoxy-7-hydroxyl-1,2,3,4-tetrahydroisoquinoline
  1,1-pentamethylenetetrahydroisoquinoline
  1,1'-(propane-1,3-diyl)-bis-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline)
  1-(2,3,4,5-tetrahydro-5-oxo-2-furyl)-2-N-(p-toluenesulfonyl)-1,2,3,4-tetrahydroisoquinoline
  1,2,3,4-tetrahydro-1,1,2,3,3,4,4-heptamethyl-6,7-dimethoxyisoquinoline
  1,2,3,4-tetrahydro-1-phenylisoquinoline
  1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline Has associated genes Has associated diseases
  1,2,3,4 tetrahydro-2-(3-mercapto-1-oxopropyl)-1-isoquinolinecarboxylic acid
  1,2,3,4-tetrahydro-4,4-dimethylisoquinoline
  1,2,3,4-tetrahydro-7-hydroxy-8-iodoisoquinoline-3-carboxylic acid
  1,2,3,4-tetrahydro-7-methoxyisoquinoline-3-carboxylic acid
  (1,2,3,4-tetrahydro-isoquinolin-1-yl)acetic acid
  1,2,3,4-tetrahydroisoquinoline Has associated genes Has associated diseases
  1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid Has associated genes Has associated diseases
  1,2,3,4-tetrahydroisoquinoline carboxylic acid
  1,2,3,4-tetrahydro-N-methyl-1-phenylisoquinoline
  1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
  1-(2-methyl-3-hydroxy-5-hydroxymethyl-4-pyridyl)-6,7-dihydroxy-1,2-3,4-tetrahydroisoquinoline
  1,3-dimethyl-1,2,3,4-tetrahydroisoquinoline
  1-(3-fluoro-4-(trifluoromethyl)phenyl)-N-(1,1,1-trifluoropropan-2-yl)-3,4-dihydroisoquinoline-2(1H)-carboxamide
  1-(3'-hydroxyphenyl)-6,7-dimethoxy-N-methyltetrahydroisoquinoline
  1-acetyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
  1-(beta-naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetra-hydroisoquinoline Has associated genes Has associated diseases
  1-cyclopropyl-6-hydroxy-8-methyl-4-oxo-7-(1,2,3,4-tetrahydro-2-isoquinolyl)-1,4-dihydroquinoline-3-carboxylic acid
  1'-heptamethylene-bis-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
  1-methyl-1,2,3,4-tetrahydroisoquinoline Has associated diseases
  1-methyl-1-phenyl-1,2,3,4-tetrahydroisoquinoline
  1-naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline Has associated genes Has associated diseases
  1-oxo-1,2,3,4-tetrahydroisoquinoline
  1-phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
  1-(pyrrolidin-1-ylmethyl)-2-((6-chloro-3-oxoindan)formyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline
  (1R)-(4-hydroxybenzyl)-7-hydroxyl-8-O-beta-D-glucopyranosyl-1,2,3,4-tetrahydroisoquinoline
  2-(5-bromo-2,3-dimethoxyphenyl)-4-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolinomethyl)imidazole
  2',6'-dimethyltyrosyl-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-alanine 1-adamantane amide
  2',6'-dimethyltyrosyl-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-phenylalanyl-phenylalaninamide
  2',6'-dimethyltyrosyl--1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-psi(CH2MH)-phenylalanyl-phenylalaninamide
  2',6'-dimethyltyrosyl-1,2,3,4-tetrahydroisoquinoline-3-carbonyl-alanyl tert-butyl amide
  2',6'-dimethyltyrosyl-1,2,3,4-tetrahydroisoquinoline-3-carbonylamino-1-adamantane
  2',6'-dimethyltyrosyl-1,2,3,4-tetrahydroisoquinoline-3-carbonyl-glycine N-benzylamide
  2',6'-dimethyltyrosyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  2-acetyl-1-(4'-chlorophenyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
  2-acetyl-1-ethyl-7-hydroxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline
  2-amino-1,2,3,4-tetrahydroisoquinoline-1,3-dione
  2-(biphenyl-4-ylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-3-carboxylic acid
  2-methoxy-4-(7-methoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)phenol
  2-methyl-1,2,3,4-tetrahydroisoquinoline
  2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
  2-naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline
  2-tyrosyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  3,4-methano-1,2,3,4,-tetrahydroisoquinoline-3-carboxylic acid
  3-carboxy-5-phosphono-1,2,3,4-tetrahydroisoquinoline
  3-chloromethyl-7-nitro-1,2,3,4-tetrahydroisoquinoline
  3-epi-jorumycin
  3-epi-renieramycin G
  3-fluoromethyl-7-cyano-1,2,3,4-tetrahydroisoquinoline
  3-methyl-1,2,3,4-tetrahydroisoquinoline
  3-methyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline
  3-trifluoromethyl-7-bromo-1,2,3,4-tetrahydroisoquinoline
  3-trifluoromethyl-7-nitro-1,2,3,4-tetrahydroisoquinoline
  4-((2-amidino-1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl)-1-(4-pyridinyl)piperidine-4-carboxylic acid monomethanesulfonate trihydrate
  4-(3,4-dihydroxyphenyl)-7-hydroxy-8-methyl-1,2,3,4-tetrahydroisoquinoline
  4-(4-bromophenyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline
  4,4-diphenyl-3-oxo-6-sulfamyl-1,2,3,4-tetrahydroisoquinoline
  458L
  4'-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-ylmethyl)biphenyl-4-ol Has associated genes Has associated diseases
  4-amino-2-cyano-1,3-dimethoxy-1,2,3,4-tetrahydroisoquinoline
  4-phenyl-1,2,3,4-tetrahydroisoquinoline Has associated genes
  (4S)-N-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline
  5,6,7,8-tetrahydro-1,3-dioxolo(4,5-g)isoquinoline
  5,6-dimethoxy-1,2,3,4-tetrahydroisoquinoline
  6,7-dihydroxy-N-cyanomethyl-1,2,3,4-tetrahydroisoquinoline
  6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  6,7-dimethoxy-2-(4-methoxybiphenyl-4-yl-methyl)-1,2,3,4-tetrahydroisoquinoline
  6,7-dimethoxy-2-(6-methoxynaphthalen-2-ylmethyl)-1,2,3,4-tetrahydroisoquinoline
  6,7-dimethoxytetrahydroisoquinoline
  7',10-dide-O-methylcephaeline
  7,8-dichloro-1,2,3,4-tetrahydroisoquinoline Has associated diseases
  7-aminosulfonyl-3-hydroxymethyl-1,2,3,4-tetrahydroisoquinoline
  7-hydroxy-N-(1-((4-(3-hydroxyphenyl)-3,4-dimethyl-1--piperidinyl)methyl)-2-methylpropyl)-1,2,3,4-tetrahydro-2-methylisoquinolinecarboxamide
  7-hydroxy-N-(1-((4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl)methyl)-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide Has associated genes Has associated diseases
  7-hydroxy-N-(1-((4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)methyl)-2-methylbutyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide dihydrochloride Has associated genes Has associated diseases
  7-isothiocyanatotetrahydroisoquinoline
  8-(4-(2-(1,2,3,4-tetrahydroisoquinolinyl))butyl)-8-azaspiro(4.5)decane-7,9-dione
  8-chloro-tetrahydroisoquinoline-7-sulfonamide
  A 69024 Has associated genes Has associated diseases
  A 71915
  abanoquil Has associated genes Has associated diseases
  AG525E1
  AIS 48
  alangiside
  ancistrocladine
  argemonine
  AR-R 18512
  ARRI 7338
  beta-methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  bisobrin
  bradykinin, Hyp(3)-Thi(5)-Tic(7)-Oic(8)-desArg(9)-
  BW 737C89
  BW 785U
  carnegine
  CGS 26529
  CH 141
  cotarnine
  CPU 23
  CPU 57
  CSH 118
  cyclo(2',6'-dimethyltyrosyl-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)
  dauricine Has associated genes Has associated diseases
  dehydrostephanine
  DL-N-(2-quinuclidinoyl)-1,2,3,4-tetrahydroisoquinoline
  DL-N-(2-quinuclidinylmethyl)-1,2,3,4-tetrahydroisoquinoline
  dynorphin A, Dmt(1)-Tic(2)-
  EDL-155
  Elacridar Has associated genes Has associated diseases
  EU 4865
  gastrofenzin
  GS 389
  heliamine
  higenamine Has associated genes Has associated diseases
  HOE 140, desArg(10)- Has associated genes Has associated diseases
  hyalachelin A
  hyalachelin B
  hyalachelin C
  hydrastinine
  hydrocotarnine Has associated diseases
  isocephaeline
  JNJ-28583867
  jorumycin
  KV-5070
  l-alpha-methyl-8-methoxy-6,7-dihydroxy-1-(6,7-dimethoxy-3-phthalidyl)-1,2,3,4-tetrahydroisoquinoline
  lemonomycin
  lemonomycinone
  lophophorine
  methyl-2',6'-dimethyltyrosinyltetrahydroisoquinoline-3-carboxylic acid
  methyl N-((2-(N-(2-amino-3-mercaptopropyl)-3-methylvalyl)-1,2,3,4-tetrahydro-3-isoquinolinyl)carbonyl)methionine
  moexipril Has associated genes Has associated diseases
  moexiprilat
  MS 857 Has associated genes Has associated diseases
  MY 336-a
  N-(1,2,3,4-tetrahydroisoquinolinium-3-ylcarbonyl)-1-(4-chlorobenzyl)-2-(4-cyclohexyl-4-(1H-1,2,4-triazol-1-ylmethyl)piperidin-1-yl)-2-oxoethylamine
  N-(1-((4-(3-carbamoylphenyl)-3,4-dimethylpiperidin-1-yl)methyl)-2-methylpropyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide Has associated genes Has associated diseases
  N-(1-((4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl)methyl)-2-methylpropyl)-7-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
  N-(2-(3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidinio)ethyl)-4-fluorobenzamide
  N-(2-bromo-4-methylphenyl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione
  N-(2-chlorobenzyl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione
  N-(2-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione
  N-((2-(N-(2-amino-3-mercaptopropyl)-3-methylvalyl)-1,2,3,4-tetrahydro-3-isoquinolinyl)carbonyl)glutamine
  N-hydroxy-2-((2,2,2-trifluoroethoxy)(4-methoxyphenyl)phosphoryl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
  N-hydroxy-2-((2,2-difluoroethoxy)(4-methoxyphenyl)phosphoryl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
  N-methylcoculaurine
  N,N'-bis-(2-carbamoyl-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolinyl)piperazine
  N,N-diethyl-2',6'-dimethyltyrosyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
  N,N-dimethyl-2',6'-dimethyltyrosyl-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl 1-adamantane amide
  N,N-dimethyl-2',6'-dimethyltyrosyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
  N,N-dimethyl-2',6'-dimethyltyrosyl-1,2,3,4-tetrahydroisoquinoline-3-carbonyl tert-butyl amide
  N,N(Me)2-dimethyl-tyrosine-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid-OH
  N-phenyltetrahydroisoquinoline
  NS-417 cpd
  oceanalin A
  oxyhydrastinine
  P91024
  PFR(Tic)amide
  phenylazo-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid
  PM 00104 Has associated genes
  quinapril Has associated genes Has associated diseases
  quinaprilat Has associated genes Has associated diseases
  (R)-1-(1H-indol-3-yl)-2-phenylmethanesulfonyl-1,2,3,4-tetrahydroisoquinoline
  renieramycin G
  renieramycin I
  renieramycin J
  renieramycin M
  renieramycin N
  renieramycin O
  RESPIR 4-95
  RP 44081
  (R)-PFI-2
  RS 42358-197
  RS 93007
  (S)-2-(2,4-hexadienoyl)-7-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
View node Salsoline Alkaloids
  SB 277011 Has associated genes Has associated diseases
  Solifenacin Succinate Has associated genes Has associated diseases
  soquinolol
  SPD 502 Has associated diseases
  TCV 309
  Tic(5) didemnin B
  toquipidine
View node Toxiferine Has associated genes Has associated diseases
  trabectedin Has associated genes Has associated diseases
  trequinsin Has associated genes Has associated diseases
  TSL 225
View node Tubocurarine Has associated genes Has associated diseases
  tylocrebrine
  tyrosyl-1,2,3,4-tetrahydro-3--isoquinoline-carbonyl-alanine
  tyrosyl 1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-phenylalanine
  tyrosyl-1,2,3,4-tetrahydro--3-isoquinolinecarbonyl-phenylalanyl-phenylalaninamide
  tyrosyl-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-phenylalanyl-phenylalanine
  tyrosyl-1,2,3,4-tetrahydro--3--isoquinolinecarbonyl-psi(CH2-NH)-cyclohexylalanyl-phenylalanine
  tyrosyl--1,2,3,4-tetrahydroisoquinoline-3-carbonyl-4-isothiocyanatophenylalanyl-phenylalanine
  tyrosyl-1,2,3,4-tetrahydroisoquinoline-3-carbonyl-phenylalanyl-4-bromoacetamidophenylalanine
  tyrosyl--1,2,3,4--tetrahydroisoquinoline-3-carbonyl-phenylalanyl-4-isothiocyanatophenylalanine
  tyrosyl-1,2,3,4--tetrahydroisoquinoline-3-carboxamide
  veronamine
  XR 9051
  YH 1885
  YS 49
  zelandopam Has associated diseases