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Chemical Thiazolidinediones

Name Thiazolidinediones
Equivalent Term Glitazones
Definition THIAZOLES with two keto oxygens. Members are insulin-sensitizing agents which overcome INSULIN RESISTANCE by activation of the peroxisome proliferator activated receptor gamma (PPAR-gamma).
Top Interacting
Genes
MeSH® ID D045162
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Top ↑ Ancestors

1. ChemicalsOrganic Chemicals Has associated genes Has associated diseases Has associated exposure references Sulfur Compounds Has associated genes Has associated diseases Has associated exposure references Thiazoles Has associated genes Has associated diseases Has associated exposure references Thiazolidinediones Has associated genes Has associated diseases
2. ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated exposure references Heterocyclic Compounds, 1-Ring Has associated genes Has associated diseases Has associated exposure references Azoles Has associated genes Has associated diseases Has associated exposure references Thiazoles Has associated genes Has associated diseases Has associated exposure references Thiazolidinediones Has associated genes Has associated diseases

Top ↑ Descendants

Thiazolidinediones Has associated genes Has associated diseases
  1,13a-dihydro-3H,5H,13H-naphtho(2,3-f)thiazolo(4,3-c)(1,4)thiazepine-5,13-dione
  1,2,4-dithiazolidine-3,5-dione
  (2-(2-Phenoxy-1-(4-bromophenyl)ethylidene)hydrazono)-5-ethylthiazolidin-4-one
  2-(3-((4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenylamino)methyl)benzamido)pentanedioic acid
  2,3-dihydro-5H-naphtho(2,3-f)thiazolo(2,3-c)(1,4)thiazepine-5,13(1aH)-dione
  2,4-thiazolidinedione Has associated genes Has associated diseases
  3-(2-aminoethyl)-5-(3-(4-butoxylphenyl)propylidene)thiazolidine-2,4-dione
  3-(2-aminoethyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione
  3-((3-((4-(4-morpholinylmethyl)-1H-pyrrol-2-yl)methylene)-2-oxo-2,3-dihydro-1H-indol-5-yl)methyl)-1,3-thiazolidine-2,4-dione
  3-(3,4-dichlorobenzyl)-5-(3,4,5-trihydroxybenzylidene)thiazolidine-2,4-dione
  3-(3,5-dichlorophenyl)-2,4-thiazolidinedione Has associated genes Has associated diseases
  3-benzyl-2-(4-fluorophenyl)-1,3-thiazolidin-4-one
  3-benzyl-5-(1H-indol-3-ylmethylene)-thiazolidine-2,4-dione
  3-benzyl-5-acridinylidene-thiazolidine-2,4-dione
  3-tert-butoxycarbonylmethyl-5-(4-(2-(N-methyl-N-(2-pyridyl)amino)ethoxy)benzyl)thiazolidine-2,4-dione
  4-(4-(2,4-dioxothiazolidin-5-ylidenemethyl)-2-methoxyphenoxy)-3-trifluoromethylbenzonitrile Has associated genes Has associated diseases
  4-(4-fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione
  4-((5-bromo-4-((2,4-dioxo-3-(2-oxo-2-phenylethyl)-1,3-thiazolidin-5-ylidene)methyl)-2-ethoxyphenoxy)methyl)benzoic acid
  5-(2,2-difluorobenzo(1,3)dioxol-5-ylmethylene)thiazolidine-2,4-dione Has associated genes Has associated diseases
  5-((2-(2-naphthalenylmethyl)-5-benzoxazolyl)methyl)-2,4-thiazolidinedione
  5-(2-chloro-3-(3-phenylpropoxy)benzylidene)thiazolidine-2,4-dione
  5-(2-naphthalenylsulfonyl)-2,4-thiazolidinedione
  5-(3-(3-(4-phenoxy-2-propylphenoxy)propoxy)phenyl)-2,4-thiazolidinedione
  5-(3,5-di-tert-butyl-4-hydroxybenzylidene)thiazolidine-2,4-dione
  5-(3-methoxyphenylidene)-2-phenylimino-3-propyl-4-thiazolidinone
  5-(4-((1-(pyridin-2-yl)pyrrolidin-2-yl)methoxy)phenylmethylene)thiazolidine-2,4-dione
  5-((4-(2-(1-indolyl)ethoxy)-phenyl)methyl)thiazolidine-2,4-dione Has associated genes Has associated diseases
  5-(4-(2-(2-ethyl-4-methyl-6-oxo-1,6-dihydro-1-pyrimidinyl)ethoxy)phenylmethyl)thiazolidine-2,4-dione Has associated genes Has associated diseases
  5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione
  5-((4-(2-(5-methyl-2-phenyl-oxazol-4-yl)ethoxy)benzo(2) thiophen-7-yl)methyl)-thiazolidine-2,4-dione
  5-(4-(5-methoxy-3-methyl-3H-imidazo(4,5-b)pyridin-2-ylmethoxy)benzyl)thiazolidine-2,4-dione
  5-(4-((6-(allyloxy)-2,5,7,8-tetramethylchroman-2-yl)methoxy)-3-methoxybenzylidene)thiazolidine-2,4-dione Has associated genes Has associated diseases
  5-(4-(6-hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl)-2,4-dioxothiazollidine, troglitazone dihydrate
  5-(4-chlorobenzylidene)-3-(4-methylbenzyl)thiazolidine-2,4-dione
  5-(4-(cyclohexylethoxy)benzylidene)-2,4-thiazolidinedione
  5-(4-(cyclopentylmethoxy)benzylidene)thiazolidine-2,4-dione
  5-(4-hydroxy-3,5-dimethylbenzylidene)thiazolidine-2,4-dione
  5-(4-hydroxy-3-trifluoromethylbenzylidene)-3-(1-methylcyclohexyl)thiazolidine-2,4-dione
  5-(4-hydroxy-3-trifluoromethylbenzylidene)-3-(4,4,4-trifluoro-2-methyl-2-(2,2,2-trifluoroethyl)butyl)thiazolidine-2,4-dione
  5-(4-methoxybenzylidene)thiazolidine-2,4-dione
  5-(4-(N-(2-pyridyl)-(2S)-pyrrolidine-2-methoxy)phenylmethylene) thiazolidine-2,6-dione
  5-(5-(4-fluoro-2-hydroxyphenyl)furan-2-ylmethylene)thiazolidine-2,4-dione
  5-((5-bromo-1H-indol-3-yl)methylene)-3-(4-chlorobenzyl)thiazolidine-2,4-dione
  5-(5-bromo-2-methoxybenzylidene)-3-(4-methyl-benzyl)thiazolidine-2,4-dione
  5-acridin-9-ylmethylene-3-(4-methyl-benzyl)-thiazolidine-2,4-dione
  5-adamantylpentanoic acid (2-(4-(2,4-dioxothiazolidin-5-ylmethyl)phenoxy)ethyl)(methyl)amide
  5-benzylidene-3-(4-methyl-benzyl)-thiazolidine-2,4-dione
  5-benzylidene thiazolidine-2,4-dione
  5-carboxymethyl-3-p-tolylthiazolidine-2,4-dione-2-acetophenone
  5-hydroxyrosiglitazone
  5-quinoxalin-6-ylmethylenethiazolidine-2,4-dione
  AD 5075
  ADD 4743
  AL 321
  balaglitazone
  BLX 1002 Has associated genes Has associated diseases
  BM 131246
  BM 501050
  CAY10415 Has associated genes Has associated diseases
  CAY10506 Has associated genes Has associated diseases
  chromonyl-2,4-thiazolidinedione
  ciglitazone Has associated genes Has associated diseases
  darglitazone Has associated genes Has associated diseases
  DN 108
  DRF 2519 Has associated genes Has associated diseases
  efatutazone Has associated genes Has associated diseases
  englitazone Has associated genes Has associated diseases
  iCTR14 compound
  lobeglitazone
  M-II compound
  M-IV compound
  MSDC-0160
  N-(2-(4-((2,4-dioxo-1,3-thiazolidin-5-yl)methyl)phenoxy)ethyl)-5-(1,2-dithiolan-3-yl)-N-methylpentanamide
  N-(3-chlorophenyl)-2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetamide Has associated genes Has associated diseases
  N-(4-(3-(1-methyl-cyclohexylmethyl)-2,4-dioxothiazolidin-5-ylidenemethyl)phenyl)-4-nitro-3-trifluoromethylbenzenesulfonamide
  N-((4-(biphenyl-2-ylmethoxy)-1-(2-(4-fluorobenzoyl)benzoyl)pyrrolidin-2-yl)methyl)-4-((2,4-dioxothiazolidin-5-ylidene)methyl)benzamide
  N-(-4-(N-(biphenyl-2-ylmethyl)-N-2-methylpropylamino)- 1-(2-(2,4-difluorobenzoyl)benzoyl)pyrrolidin- 2-yl)methyl-3-(4-(2,4-dioxothiazolidin-5-ylidenemethyl) phenyl)acrylamide Has associated genes Has associated diseases
  N-desmethylrosiglitazone
  netoglitazone Has associated genes Has associated diseases
  NIP-222
  OSU-53
  OSU-CG5
  pioglitazone Has associated genes Has associated diseases
  R 147176
  risarestat
  rivoglitazone
  rosiglitazone Has associated genes Has associated diseases
  SB-271258
  TD49 thiazolidinedione
  thiazolidine-2,4-dione
  thiazolidine-2,4-thione
  thiazolidinedione-8
  troglitazone Has associated genes Has associated diseases
  troglitazone sulfate Has associated genes Has associated diseases
  (Z)2-(5-(4-methoxybenzylidene)-2,4-dioxothiazolidin-3-yl)acetic acid
  (Z)-5-(2,4-dihydroxybenzylidene)thiazolidine-2,4-dione
  ZINC17167211