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Chemical Molecular Mechanisms of Pharmacological Action

These are exposure studies associated with the chemical and all of its children.

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1–4 of 4 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Solfrizzi V, et al. (2013). Italian Longitudinal Study on Aging (ILSA) Using a large, population-based cohort, we investigated whether angiotensin-converting enzyme inhibitors collectively as a 'class' and as sub-groups according to their chemical structures and drug potencies, compared with other antihypertensive agents and beyond the natural course in time of the hypertension, reduced the incidence of mild cognitive impairment in cognitively normal individuals. Angiotensin-Converting Enzyme Inhibitors | Enalapril | Lisinopril Subjects with disease:Hypertension Italy Details Cognitive Dysfunction
2. Wilker E, et al. (2009). Normative Aging Study (NAS) Particulate Matter <=2.5 microns in diameter influences blood pressure and autonomic function. This effect is modified by genes and drugs that also act along this pathway. genetics Angiotensin Receptor Antagonists | Particulate Matter Subjects with gene influence:ITPR2 | Military personnel | Subjects with gene influence:MMP1 | Subjects with gene influence:PHF11 United States air Particulate Matter Details regulation of blood pressure
3. Reynolds P, et al. (2005). The results from this study provide no evidence that California women living in areas of recent, high agricultural pesticide use experience higher rates of breast cancer. Pesticides Subjects with disease:Breast Neoplasms United States Carcinogens | Cholinesterase Inhibitors | Diuron | Hydrocarbons, Chlorinated | methyl bromide | Omite | oryzalin | Simazine Details Breast Neoplasms
4. Colvin L, et al. (2012). Children born to mothers using a selective serotonin reuptake inhibitor were more likely to be admitted to a hospital in the first years of life, and although the numbers of deaths in the first year of life were small, the increased risk is a new finding and should be investigated further. Serotonin Uptake Inhibitors Pregnant females Australia Details Death | Fetal Diseases
1–4 of 4 results.