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Chemical Molecular Mechanisms of Pharmacological Action

1–50 of 534 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. Adenylyl Cyclase Inhibitors obsolete positive regulation of cAMP biosynthetic process Adenylyl Cyclase Inhibitors results in decreased obsolete positive regulation of cAMP biosynthetic process 1: Homo sapiens Hep G2 Cells   1
2. Adenylyl Cyclase Inhibitors positive regulation of autophagosome assembly resveratrol Adenylyl Cyclase Inhibitors inhibits the reaction [resveratrol results in increased positive regulation of autophagosome assembly] 1: Homo sapiens Hep G2 Cells   1
3. Adenylyl Cyclase Inhibitors positive regulation of autophagosome assembly Adenylyl Cyclase Inhibitors results in decreased positive regulation of autophagosome assembly 1: Homo sapiens Hep G2 Cells   1
4. Adenylyl Cyclase Inhibitors obsolete regulation of cAMP metabolic process Cyclic AMP | resveratrol Adenylyl Cyclase Inhibitors inhibits the reaction [[resveratrol affects obsolete regulation of cAMP metabolic process] which results in increased abundance of Cyclic AMP] 1: Homo sapiens Hep G2 Cells   1
5. Adenylyl Cyclase Inhibitors obsolete regulation of cAMP metabolic process resveratrol Adenylyl Cyclase Inhibitors inhibits the reaction [resveratrol affects obsolete regulation of cAMP metabolic process] 1: Homo sapiens Hep G2 Cells   1
6. Adrenergic alpha-Antagonists vasoconstriction Morphine Adrenergic alpha-Antagonists inhibits the reaction [Morphine results in increased vasoconstriction] 1: Canis lupus familiaris Heart | Blood Vessels   1
7. Adrenergic alpha-Antagonists regulation of blood pressure Adrenergic beta-Antagonists | Nifedipine [Nifedipine co-treated with Adrenergic alpha-Antagonists co-treated with Adrenergic beta-Antagonists] results in decreased regulation of blood pressure 1: Homo sapiens Blood Vessels   1
8. Adrenergic beta-Antagonists regulation of heart rate Adrenergic beta-Antagonists affects regulation of heart rate 1: Homo sapiens Cardiovascular System   1
9. Adrenergic beta-Antagonists vasoconstriction Adrenergic beta-Antagonists results in increased vasoconstriction 1: Homo sapiens Blood Vessels   1
10. Adrenergic beta-Antagonists regulation of blood pressure Adrenergic beta-Antagonists results in decreased regulation of blood pressure 1: Homo sapiens Cardiovascular System 1 gene: NPPB 1
11. Adrenergic beta-Antagonists vasodilation Adrenergic beta-Antagonists results in increased vasodilation 1: Homo sapiens Cardiovascular System   1
12. Adrenergic beta-Antagonists vasodilation Aspirin Aspirin inhibits the reaction [Adrenergic beta-Antagonists results in increased vasodilation] 1: Homo sapiens Cardiovascular System   1
13. Adrenergic beta-Antagonists lipid catabolic process Octopamine Adrenergic beta-Antagonists inhibits the reaction [Octopamine results in increased lipid catabolic process] 1: Rattus norvegicus Adipocytes, White   1
14. Adrenergic beta-Antagonists regulation of blood pressure Felodipine [Felodipine co-treated with Adrenergic beta-Antagonists] results in decreased regulation of blood pressure 1: Homo sapiens Cardiovascular System 1 gene: NPPB 1
15. Adrenergic beta-Antagonists vasoconstriction Nicardipine Nicardipine inhibits the reaction [Adrenergic beta-Antagonists results in increased vasoconstriction] 1: Homo sapiens Blood Vessels   1
16. Adrenergic beta-Antagonists regulation of heart rate Isoproterenol Adrenergic beta-Antagonists affects the reaction [Isoproterenol results in increased regulation of heart rate] 1: Homo sapiens Heart   1
17. Adrenergic beta-Antagonists regulation of blood pressure Diuretics | Minoxidil [Diuretics co-treated with Minoxidil co-treated with Adrenergic beta-Antagonists] results in decreased regulation of blood pressure 1: Homo sapiens Cardiovascular System 1 gene: NPPB 1
18. Adrenergic beta-Antagonists regulation of blood pressure Adrenergic alpha-Antagonists | Nifedipine [Nifedipine co-treated with Adrenergic alpha-Antagonists co-treated with Adrenergic beta-Antagonists] results in decreased regulation of blood pressure 1: Homo sapiens Blood Vessels 1 gene: NPPB 1
19. Adrenergic beta-Antagonists regulation of heart rate Isoproterenol Adrenergic beta-Antagonists inhibits the reaction [Isoproterenol results in increased regulation of heart rate] 1: Homo sapiens Heart   1
20. Adrenergic beta-Antagonists regulation of blood pressure Isradipine Adrenergic beta-Antagonists promotes the reaction [Isradipine results in decreased regulation of blood pressure] 1: Homo sapiens Cardiovascular System 1 gene: NPPB 1
21. Adrenergic beta-Antagonists vasoconstriction Epinephrine [Epinephrine co-treated with Adrenergic beta-Antagonists] results in increased vasoconstriction 1: Homo sapiens Blood Vessels   1
22. Angiotensin-Converting Enzyme Inhibitors regulation of blood pressure Aldosterone [Angiotensin-Converting Enzyme Inhibitors results in decreased regulation of blood pressure] which results in decreased abundance of Aldosterone 1: Homo sapiens Cardiovascular System
6 genes: ACE | AGT | EDN1 | NPPA | NPPB | REN
2
23. Angiotensin-Converting Enzyme Inhibitors vasodilation Aspirin Aspirin inhibits the reaction [Angiotensin-Converting Enzyme Inhibitors results in increased vasodilation] 1: Homo sapiens Cardiovascular System
2 genes: AGT | KNG1
1
24. Angiotensin-Converting Enzyme Inhibitors regulation of organ growth Angiotensin-Converting Enzyme Inhibitors results in decreased regulation of organ growth 2: Mus musculus | Rattus norvegicus Heart   2
25. Angiotensin-Converting Enzyme Inhibitors regulation of blood pressure Angiotensin-Converting Enzyme Inhibitors results in decreased regulation of blood pressure 4: Canis lupus familiaris | Homo sapiens | Mus musculus | Rattus norvegicus Cardiovascular System
6 genes: ACE | AGT | EDN1 | NPPA | NPPB | REN
29
26. Angiotensin-Converting Enzyme Inhibitors apoptotic process Angiotensin-Converting Enzyme Inhibitors results in decreased apoptotic process 1: Homo sapiens Lung | Epithelial Cells
7 genes: AVP | BAX | BCL2 | EPO | FAS | FASLG | GAS6
1
27. Angiotensin-Converting Enzyme Inhibitors apoptotic process desethylamiodarone Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [desethylamiodarone results in increased apoptotic process] 1: Rattus norvegicus Pulmonary Alveoli | Epithelium | Cells, Cultured
7 genes: AVP | BAX | BCL2 | EPO | FAS | FASLG | GAS6
1
28. Angiotensin-Converting Enzyme Inhibitors regulation of blood pressure REN [Angiotensin-Converting Enzyme Inhibitors results in decreased regulation of blood pressure] which results in increased expression of and affects the activity of REN protein 1: Homo sapiens Cardiovascular System
6 genes: ACE | AGT | EDN1 | NPPA | NPPB | REN
1
29. Angiotensin-Converting Enzyme Inhibitors glomerular filtration Angiotensin-Converting Enzyme Inhibitors affects glomerular filtration 1: Rattus norvegicus Kidney   2
30. Angiotensin-Converting Enzyme Inhibitors regulation of blood pressure Angiotensin-Converting Enzyme Inhibitors affects regulation of blood pressure 1: Rattus norvegicus Cardiovascular System
6 genes: ACE | AGT | EDN1 | NPPA | NPPB | REN
1
31. Angiotensin-Converting Enzyme Inhibitors renal sodium excretion AGT | Furosemide AGT protein inhibits the reaction [Angiotensin-Converting Enzyme Inhibitors promotes the reaction [Furosemide results in increased renal sodium excretion]] 1: Homo sapiens Kidney   1
32. Angiotensin-Converting Enzyme Inhibitors vasoconstriction AGT Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [AGT results in increased vasoconstriction] 1: Rattus norvegicus Kidney
4 genes: ACE | AGT | AVP | EDN1
2
33. Angiotensin-Converting Enzyme Inhibitors regulation of blood pressure Nifedipine Nifedipine promotes the reaction [Angiotensin-Converting Enzyme Inhibitors results in decreased regulation of blood pressure] 1: Homo sapiens Cardiovascular System
6 genes: ACE | AGT | EDN1 | NPPA | NPPB | REN
1
34. Angiotensin-Converting Enzyme Inhibitors vasoconstriction Angiotensin-Converting Enzyme Inhibitors results in decreased vasoconstriction 1: Rattus norvegicus Kidney
4 genes: ACE | AGT | AVP | EDN1
1
35. Angiotensin-Converting Enzyme Inhibitors regulation of blood pressure Desoxycorticosterone | Sodium Chloride, Dietary | Vasopressins [Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [[Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased regulation of blood pressure]] which results in decreased abundance of Vasopressins 1: Rattus norvegicus Cardiovascular System
6 genes: ACE | AGT | EDN1 | NPPA | NPPB | REN
1
36. Angiotensin-Converting Enzyme Inhibitors apoptotic process FAS Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [FAS results in increased apoptotic process] 1: Homo sapiens T-Lymphocytes
7 genes: AVP | BAX | BCL2 | EPO | FAS | FASLG | GAS6
1
37. Angiotensin-Converting Enzyme Inhibitors apoptotic process Angiotensin-Converting Enzyme Inhibitors results in decreased apoptotic process 1: Rattus norvegicus Lung
7 genes: AVP | BAX | BCL2 | EPO | FAS | FASLG | GAS6
1
38. Angiotensin-Converting Enzyme Inhibitors regulation of blood pressure Nitrendipine [Nitrendipine co-treated with Angiotensin-Converting Enzyme Inhibitors] results in decreased regulation of blood pressure 1: Homo sapiens Blood Vessels
6 genes: ACE | AGT | EDN1 | NPPA | NPPB | REN
1
39. Angiotensin-Converting Enzyme Inhibitors response to oxidative stress Angiotensin-Converting Enzyme Inhibitors results in decreased response to oxidative stress 1: Rattus norvegicus Cardiovascular System
3 genes: BCL2 | MMP2 | MMP9
1
40. Angiotensin-Converting Enzyme Inhibitors vasoconstriction Norepinephrine Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Norepinephrine results in increased vasoconstriction] 1: Rattus norvegicus Kidney
4 genes: ACE | AGT | AVP | EDN1
2
41. Angiotensin-Converting Enzyme Inhibitors regulation of blood pressure Benzodiazepines | Cocaine [Benzodiazepines co-treated with Angiotensin-Converting Enzyme Inhibitors] inhibits the reaction [Cocaine results in increased regulation of blood pressure] 1: Rattus norvegicus Blood Vessels
6 genes: ACE | AGT | EDN1 | NPPA | NPPB | REN
1
42. Angiotensin-Converting Enzyme Inhibitors regulation of blood pressure ditekiren Angiotensin-Converting Enzyme Inhibitors promotes the reaction [ditekiren results in decreased regulation of blood pressure] 1: Macaca fascicularis Cardiovascular System
6 genes: ACE | AGT | EDN1 | NPPA | NPPB | REN
1
43. Angiotensin-Converting Enzyme Inhibitors regulation of blood pressure Aldosterone | Nifedipine [Angiotensin-Converting Enzyme Inhibitors promotes the reaction [Nifedipine results in decreased regulation of blood pressure]] which results in decreased abundance of Aldosterone 1: Homo sapiens Cardiovascular System
6 genes: ACE | AGT | EDN1 | NPPA | NPPB | REN
1
44. Angiotensin-Converting Enzyme Inhibitors response to oxidative stress Paraquat Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Paraquat results in increased response to oxidative stress] 1: Rattus norvegicus Mitochondria, Liver
3 genes: BCL2 | MMP2 | MMP9
1
45. Angiotensin-Converting Enzyme Inhibitors apoptotic process FAS Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [FAS results in increased apoptotic process] 1: Homo sapiens Lung | Epithelial Cells
7 genes: AVP | BAX | BCL2 | EPO | FAS | FASLG | GAS6
1
46. Angiotensin-Converting Enzyme Inhibitors positive regulation of urine volume Angiotensin-Converting Enzyme Inhibitors results in increased positive regulation of urine volume 1: Homo sapiens Cardiovascular System
2 genes: EDN1 | NPPB
1
47. Angiotensin-Converting Enzyme Inhibitors vasodilation Angiotensin-Converting Enzyme Inhibitors results in increased vasodilation 2: Canis lupus familiaris | Homo sapiens Cardiovascular System
2 genes: AGT | KNG1
3
48. Angiotensin-Converting Enzyme Inhibitors apoptotic process desethylamiodarone Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [desethylamiodarone results in increased apoptotic process] 1: Homo sapiens Lung | Cell Line, Tumor
7 genes: AVP | BAX | BCL2 | EPO | FAS | FASLG | GAS6
1
49. Angiotensin-Converting Enzyme Inhibitors response to oxidative stress Angiotensin-Converting Enzyme Inhibitors results in decreased response to oxidative stress 1: Homo sapiens Human Umbilical Vein Endothelial Cells
3 genes: BCL2 | MMP2 | MMP9
1
50. Angiotensin-Converting Enzyme Inhibitors regulation of blood pressure Angiotensin-Converting Enzyme Inhibitors results in decreased regulation of blood pressure 1: Homo sapiens Forearm | Cardiovascular System
6 genes: ACE | AGT | EDN1 | NPPA | NPPB | REN
1
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