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Chemical Therapeutic Uses

These are exposure studies associated with the chemical and all of its children.

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1–13 of 13 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Smarr MM, et al. (2017). Longitudinal Investigation of Fertility and the Environment Study (LIFE) Higher quartiles of preconception urinary concentrations of methyl paraben and ethyl paraben among female partners were associated with reduced couple fecundity in partner-specific and couple-based exposure models. sex 4-hydroxybenzoic acid | Anti-Infective Agents | benzylparaben | butylparaben | ethyl-p-hydroxybenzoate | heptylparaben | methylparaben | Parabens | propylparaben | protocatechuic acid | triclocarban | Triclosan Study subjects United States urine 4-hydroxybenzoic acid | benzylparaben | butylparaben | Creatinine | ethyl-p-hydroxybenzoate | heptylparaben | methylparaben | propylparaben | protocatechuic acid | triclocarban | Triclosan Details Infertility, Female | reproductive process
2. Kaye JA, et al. (2014). The results support a comparatively high adjusted relative risk of liver injury among patients exposed concurrently to multiple antimicrobials and modest elevations in the risk for several antimicrobials used alone; however, we found little evidence of any strong effect of commonly used antimicrobials on the risk of liver injury. Amoxicillin | Anti-Infective Agents | Clavulanic Acid | Doxycycline | Levofloxacin | moxifloxacin Study subjects United States Details Chemical and Drug Induced Liver Injury
3. Adgent MA, et al. (2015). National Health and Nutrition Examination Survey (NHANES) Antibiotics, but not triclosan, are negatively associated with urinary enterolactone; further study of triclosan exposure and enterolactone production may be needed to better understand positive associations among women. age | body mass index | diet | race | sex | socioeconomic status Anti-Bacterial Agents | Lincomycin | Macrolides | Quinolones | Sulfonamides | Triclosan Study subjects United States urine 2,3-bis(3'-hydroxybenzyl)butyrolactone | Triclosan Details
4. Mogensen DM, et al. (2017). Odense Child Cohort In this preliminary study, the use of antifungal medicine in the prenatal window of male genital development between 8-14 weeks of gestation was associated with a larger reduction in ano-scrotal distance than exposure outside this window. age | sex Antifungal Agents | Fluconazole Children | Fetuses | Pregnant females Denmark Details Prenatal Exposure Delayed Effects | male genitalia morphogenesis
5. Guthikonda K, et al. (2014). This study represents the first report of an interaction of genetic variation and DNA-methylation of GATA3 on the risk for asthma at 18 years, which is modified by the use of oral contraceptive pills and age at menarche. Contraceptives, Oral Subjects with gene influence:GATA3 United Kingdom Details Asthma
6. Rava M, et al. (2017). Epidemiological family-based study of the Genetics and Environment of Asthma (EGEA) | European Community Respiratory Health Survey (ECRHS) | Swiss study on Air Pollution and Lung Diseases In Adults (SAPALDIA) This study identified interactions between genetic variants near or within five genes, PLA2G4A, PLA2R1, RELA, PRKD1 and PRKCA, and occupational exposures to low molecular weight agents or irritants for current adult-onset asthma. Detergents | Disinfectants Subjects with gene influence:PLA2G4A | Subjects with gene influence:PLA2R1 | Subjects with gene influence:PRKCA | Subjects with gene influence:PRKD1 | Subjects with gene influence:RELA | Workers France|Switzerland Details Asthma, Occupational
7. Schlumpf M, et al. (2010). We present data on chemicals in human milk of 54 mother/child pairs, where for the first time cosmetic UV filters (sunscreens), synthetic musks, parabens, and phthalate metabolites were analyzed in the same sample along with persistent organochlor pollutants, polybrominated diphenylethers, and polychlorinated biphenyls. diet Dibutyl Phthalate | Diethylhexyl Phthalate | diisobutyl phthalate | Parabens | Perfume | Pesticides | Polybrominated Biphenyls | Polychlorinated Biphenyls | Sunscreening Agents Infants or newborns | Mothers Switzerland milk, human 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | acetyl methyl tetramethyl tetralin | alpha-hexachlorocyclohexane | beta-hexachlorocyclohexane | Chlordan | chlorpyrifos-ethyl | DDT | Dichlorodiphenyl Dichloroethylene | Dieldrin | enzacamene | ethylhexyl methoxycinnamate | ethyl-p-hydroxybenzoate | galaxolide | Heptachlor | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | homosalate | Lindane | methylparaben | mono-(2-ethylhexyl)phthalate | monobutyl phthalate | mono-isobutyl phthalate | musk ketone | musk xylene | nonachlor | octocrylene | octyl dimethyl 4-aminobenzoic acid | o,p'-DDT | oxybenzone | oxychlordane | PCB 180 | pentabrominated diphenyl ether 100 | phantolid | Polychlorinated Biphenyls | propylparaben | Toxaphene | tribromodiphenyl ether 28 Details
8. Park DU, et al. (2015). We conducted a comprehensive humidifier disinfectant exposure characterization for 374 subjects with lung disease who presumed their disease was related to humidifier disinfectant use (patient group) and for 303 of their family members (family group) for an ongoing epidemiological study. Disinfectants Children | Controls for disease:Lung Diseases | Subjects with disease:Lung Diseases | Pregnant females Korea, Republic of Disinfectants Details
9. Hahn S, et al. (2010). Exposure to biocides from household products may contribute to induction of sensitization in the population. Disinfectants Germany 1,2-benzisothiazoline-3-one | 2-Propanol | Benzalkonium Compounds | Benzoates | bronopol | chloroacetamide | Chlorpyrifos | d,d-T80-prallethrin | Dichlorvos | Formaldehyde | Glutaral | Hydrogen Peroxide | phenoxyethanol | phoxim | picaridin | Sodium Hypochlorite | Thiazoles | trichloroisocyanuric acid | Triclosan | troclosene Details
10. No authors listed. (2011). National Electronic Injury Surveillance System (NEISS) | Sentinel Event Notification System for Occupational Risks (SENSOR) To assess the frequency of illness and injury related to pool chemicals, Centers for Disease Control analyzed data for the period 2002-2008 from six states participating in the Sentinel Event Notification System for Occupational Risk (SENSOR)-Pesticides surveillance program and from the National Electronic Injury Surveillance System (NEISS). Disinfectants Study subjects United States Details Acute Disease | Occupational Diseases | Respiratory Tract Diseases
11. Park DU, et al. (2015). The use of household humidifier disinfectants was associated with humidifier disinfectant-associated lung injury risk in a dose-response manner. Disinfectants Controls for disease:Lung Injury | Subjects with disease:Lung Injury Korea, Republic of Disinfectants Details Lung Injury
12. Brevard TA, et al. (2003). In this study, we addressed the need for more information on chemical exposures in the workplace and found that working youths are at a higher risk of acute occupational disinfectant related illness than are adults. Disinfectants | Halogens | Phenols | Quaternary Ammonium Compounds Children United States Details Acute Disease | Occupational Diseases
13. Z'gambo J, et al. (2016). This study sought to characterize acute poisoning with regard to demographic factors (i.e. age, sex and residence), common toxic agents used and their case fatality rates as well as the overall mortality rate of acute poisoning. Narcotics | Pesticides Children | Study subjects Zambia Details Poisoning
1–13 of 13 results.