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Chemical Macrocyclic Compounds

1–50 of 2,965 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 15-acetyldeoxynivalenol estrogen receptor activity 15-acetyldeoxynivalenol results in increased estrogen receptor activity 1: Homo sapiens     1
2. 15-acetyldeoxynivalenol estrogen receptor activity 3-acetyldeoxynivalenol | deoxynivalenol | zearalenol | Zearalenone [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in increased estrogen receptor activity 1: Homo sapiens     1
3. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin cell cycle 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin results in decreased cell cycle 1: Homo sapiens B-Lymphocytes | Cell Line, Tumor
8 genes: BUB1B | CCND1 | CDK4 | CDKN1A | CDKN1B | CHEK1 | PTTG1 | TP53
1
4. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin apoptotic process 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin results in increased apoptotic process 1: Homo sapiens B-Lymphocytes | Cell Line, Tumor
9 genes: BUB1B | CASP3 | CASP9 | CHEK1 | HMOX1 | PARP1 | RAF1 | TNF | TP53
1
5. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin apoptotic process Vorinostat [17-(dimethylaminoethylamino)-17-demethoxygeldanamycin co-treated with Vorinostat] results in increased apoptotic process 1: Homo sapiens B-Lymphocytes | Cell Line, Tumor
9 genes: BUB1B | CASP3 | CASP9 | CHEK1 | HMOX1 | PARP1 | RAF1 | TNF | TP53
1
6. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin apoptotic process Vorinostat [17-(dimethylaminoethylamino)-17-demethoxygeldanamycin co-treated with Vorinostat] results in increased apoptotic process 1: Homo sapiens B-Lymphocytes | Tumor Cells, Cultured
9 genes: BUB1B | CASP3 | CASP9 | CHEK1 | HMOX1 | PARP1 | RAF1 | TNF | TP53
1
7. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin cell proliferation Rotenone 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Rotenone results in decreased cell proliferation] 1: Homo sapiens Neurons | Cell Line, Tumor
6 genes: ALK | BUB1B | CDK4 | MYC | RAF1 | TP53
1
8. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin reactive oxygen species metabolic process Rotenone 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Rotenone results in increased reactive oxygen species metabolic process] 1: Homo sapiens Neurons | Cell Line, Tumor   1
9. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin cell proliferation Cadmium Chloride 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Cadmium Chloride results in decreased cell proliferation] 1: Oncorhynchus mykiss Liver | Cell Line, Tumor
6 genes: ALK | BUB1B | CDK4 | MYC | RAF1 | TP53
1
10. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin creatine kinase activity Lipopolysaccharides 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Lipopolysaccharides results in increased creatine kinase activity] 1: Rattus norvegicus Plasma   1
11. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin lactate dehydrogenase activity Lipopolysaccharides 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Lipopolysaccharides results in increased lactate dehydrogenase activity] 1: Rattus norvegicus Plasma   1
12. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin creatine kinase activity Lipopolysaccharides | Quercetin Quercetin inhibits the reaction [17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Lipopolysaccharides results in increased creatine kinase activity]] 1: Rattus norvegicus Plasma   1
13. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin nitric oxide metabolic process Lipopolysaccharides 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Lipopolysaccharides results in increased nitric oxide metabolic process] 1: Rattus norvegicus Plasma   1
14. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin nitric oxide metabolic process Lipopolysaccharides | Quercetin Quercetin inhibits the reaction [17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Lipopolysaccharides results in increased nitric oxide metabolic process]] 1: Rattus norvegicus Plasma   1
15. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin superoxide anion generation Lipopolysaccharides 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Lipopolysaccharides results in increased superoxide anion generation] 1: Rattus norvegicus Heart Ventricles | Myocardium   1
16. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin glutathione biosynthetic process Lipopolysaccharides [17-(dimethylaminoethylamino)-17-demethoxygeldanamycin co-treated with Lipopolysaccharides] results in increased glutathione biosynthetic process 1: Rattus norvegicus Heart Ventricles | Myocardium   1
17. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin leukocyte migration involved in inflammatory response Lipopolysaccharides 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Lipopolysaccharides results in increased leukocyte migration involved in inflammatory response] 1: Rattus norvegicus Lung | Pulmonary Alveoli   1
18. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin leukocyte migration involved in inflammatory response Lipopolysaccharides | Quercetin Quercetin inhibits the reaction [17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Lipopolysaccharides results in increased leukocyte migration involved in inflammatory response]] 1: Rattus norvegicus Lung | Pulmonary Alveoli   1
19. 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin positive regulation of apoptotic DNA fragmentation Arsenic Trioxide [17-(dimethylaminoethylamino)-17-demethoxygeldanamycin co-treated with Arsenic Trioxide] results in increased positive regulation of apoptotic DNA fragmentation 1: Rattus norvegicus Osteoblasts | Cells, Cultured   1
20. 2-Hydroxypropyl-beta-cyclodextrin regulation of ATP metabolic process Phenylpropanolamine 2-Hydroxypropyl-beta-cyclodextrin inhibits the reaction [Phenylpropanolamine affects regulation of ATP metabolic process] 1: Homo sapiens Neural Stem Cells | Cell Line, Tumor   1
21. 2-Hydroxypropyl-beta-cyclodextrin regulation of ATP metabolic process Adenosine Triphosphate | Phenylpropanolamine 2-Hydroxypropyl-beta-cyclodextrin inhibits the reaction [[Phenylpropanolamine affects regulation of ATP metabolic process] which results in decreased abundance of Adenosine Triphosphate] 1: Homo sapiens Neural Stem Cells | Cell Line, Tumor   1
22. 2-Hydroxypropyl-beta-cyclodextrin positive regulation of necroptotic process Phenylpropanolamine 2-Hydroxypropyl-beta-cyclodextrin inhibits the reaction [Phenylpropanolamine results in increased positive regulation of necroptotic process] 1: Homo sapiens Neural Stem Cells | Cell Line, Tumor   1
23. 2-Hydroxypropyl-beta-cyclodextrin cholesterol transport involved in cholesterol storage Phenylpropanolamine 2-Hydroxypropyl-beta-cyclodextrin inhibits the reaction [Phenylpropanolamine results in increased cholesterol transport involved in cholesterol storage] 1: Homo sapiens Neural Stem Cells | Cell Line, Tumor   1
24. 2-Hydroxypropyl-beta-cyclodextrin positive regulation of cholesterol efflux 2-Hydroxypropyl-beta-cyclodextrin results in increased positive regulation of cholesterol efflux 1: Homo sapiens Neural Stem Cells | Cell Line, Tumor
2 genes: ABCA1 | NR1H3
1
25. 2-Hydroxypropyl-beta-cyclodextrin positive regulation of cholesterol efflux 24-hydroxycholesterol [2-Hydroxypropyl-beta-cyclodextrin results in increased positive regulation of cholesterol efflux] which results in increased secretion of 24-hydroxycholesterol 1: Homo sapiens Neural Stem Cells | Cell Line, Tumor
2 genes: ABCA1 | NR1H3
1
26. 2-Hydroxypropyl-beta-cyclodextrin glutamate dehydrogenase (NADP+) activity 2-Hydroxypropyl-beta-cyclodextrin results in increased glutamate dehydrogenase (NADP+) activity 1: Rattus norvegicus Plasma   1
27. 2-Hydroxypropyl-beta-cyclodextrin L-aspartate:2-oxoglutarate aminotransferase activity 2-Hydroxypropyl-beta-cyclodextrin results in increased L-aspartate:2-oxoglutarate aminotransferase activity 1: Rattus norvegicus Plasma   1
28. 2-Hydroxypropyl-beta-cyclodextrin micturition 2-Hydroxypropyl-beta-cyclodextrin results in decreased micturition 1: Rattus norvegicus     1
29. 3-acetyldeoxynivalenol estrogen receptor activity 3-acetyldeoxynivalenol results in increased estrogen receptor activity 1: Homo sapiens     1
30. 3-acetyldeoxynivalenol estrogen receptor activity 15-acetyldeoxynivalenol | deoxynivalenol | zearalenol | Zearalenone [15-acetyldeoxynivalenol co-treated with 3-acetyldeoxynivalenol co-treated with deoxynivalenol co-treated with zearalenol co-treated with Zearalenone] results in increased estrogen receptor activity 1: Homo sapiens     1
31. 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride apoptotic process Hemin 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride inhibits the reaction [Hemin results in increased apoptotic process] 1: Mus musculus Cell Line | Cerebral Cortex | Microvessels
5 genes: BAX | BCL2 | CASP3 | HMOX1 | PARP1
1
32. 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride positive regulation of cell death Doxorubicin | Rosiglitazone 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride inhibits the reaction [[Doxorubicin co-treated with Rosiglitazone] results in increased positive regulation of cell death] 1: Homo sapiens Breast | Cell Line, Tumor 1 gene: HMGB1 1
33. 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride positive regulation of cell death Docetaxel | Rosiglitazone 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride inhibits the reaction [[Docetaxel co-treated with Rosiglitazone] results in increased positive regulation of cell death] 1: Homo sapiens Breast | Cell Line, Tumor 1 gene: HMGB1 1
34. 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride peptidyl-tyrosine modification Blood Glucose | Oxygen 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron(III) chloride inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased peptidyl-tyrosine modification] 1: Rattus norvegicus Myocardium   1
35. 5,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III) peptidyl-tyrosine modification Mevinphos | Peroxynitrous Acid 5,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III) inhibits the reaction [Mevinphos promotes the reaction [Peroxynitrous Acid results in increased peptidyl-tyrosine modification]] 1: Rattus norvegicus Medulla Oblongata   1
36. 5,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III) neurological system process involved in regulation of systemic arterial blood pressure Mevinphos 5,10,15,20-tetrakis(N-methyl-4'-pyridyl)porphyrinato-iron(III) inhibits the reaction [Mevinphos affects neurological system process involved in regulation of systemic arterial blood pressure] 1: Rattus norvegicus Cardiovascular System   1
37. 5,15-diphenylporphyrin reactive oxygen species biosynthetic process Etoposide 5,15-diphenylporphyrin inhibits the reaction [Etoposide results in increased reactive oxygen species biosynthetic process] 1: Homo sapiens MCF-7 Cells   1
38. ado-trastuzumab emtansine mitotic cell cycle arrest ado-trastuzumab emtansine results in increased mitotic cell cycle arrest 1: Rattus norvegicus Liver | Hepatocytes   1
39. ado-trastuzumab emtansine mitotic cell cycle arrest ado-trastuzumab emtansine results in increased mitotic cell cycle arrest 1: Rattus norvegicus Liver | Bile Ducts | Epithelium   1
40. ado-trastuzumab emtansine mitotic cell cycle arrest ado-trastuzumab emtansine results in increased mitotic cell cycle arrest 2: Macaca fascicularis | Rattus norvegicus Liver | Kupffer Cells   1
41. ado-trastuzumab emtansine mitotic cell cycle arrest ado-trastuzumab emtansine results in increased mitotic cell cycle arrest 1: Macaca fascicularis Spleen | Cells   1
42. ado-trastuzumab emtansine mitotic cell cycle arrest ado-trastuzumab emtansine results in increased mitotic cell cycle arrest 1: Macaca fascicularis Kidney | Epithelium | Cells   1
43. ado-trastuzumab emtansine mitotic cell cycle arrest ado-trastuzumab emtansine results in increased mitotic cell cycle arrest 1: Macaca fascicularis Tongue | Epithelium | Cells   1
44. ado-trastuzumab emtansine mitotic cell cycle arrest ado-trastuzumab emtansine results in increased mitotic cell cycle arrest 1: Macaca fascicularis Mandible | Salivary Glands | Acinar Cells   1
45. ado-trastuzumab emtansine mitotic cell cycle arrest ado-trastuzumab emtansine results in increased mitotic cell cycle arrest 1: Macaca fascicularis Skin | Epithelium | Cells   1
46. ado-trastuzumab emtansine cell proliferation ado-trastuzumab emtansine results in decreased cell proliferation 1: Homo sapiens Breast | Cell Line, Tumor
2 genes: AKT1 | ERBB2
1
47. ado-trastuzumab emtansine mitotic cell cycle arrest ado-trastuzumab emtansine results in increased mitotic cell cycle arrest 1: Homo sapiens Breast | Cell Line, Tumor   1
48. ado-trastuzumab emtansine mitotic cell cycle arrest palbociclib [palbociclib co-treated with ado-trastuzumab emtansine] results in increased mitotic cell cycle arrest 1: Homo sapiens Breast | Cell Line, Tumor   1
49. AEOL 10150 cell death Paraquat | TXNRD2 AEOL 10150 inhibits the reaction [TXNRD2 mutant form promotes the reaction [Paraquat results in increased cell death]] 1: Rattus norvegicus Dopaminergic Neurons | Cell Line   1
50. AEOL 10150 positive regulation of oxidative stress-induced neuron death Isoflurophate AEOL 10150 inhibits the reaction [Isoflurophate results in increased positive regulation of oxidative stress-induced neuron death] 1: Rattus norvegicus Piriform Cortex   1
1–50 of 2,965 results.