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Chemical Tumor Necrosis Factors

Name Tumor Necrosis Factors
Equivalent Terms Necrosis Factors, Tumor | Receptor Ligands, TNF | TNF Receptor Ligands | Tumor Necrosis Factor Superfamily Ligands
Definition A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D048069
External Links

Top ↑ Ancestors

ChemicalsBiological Factors Has associated genes Has associated diseases Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Cytokines Has associated genes Has associated diseases Tumor Necrosis Factors

Top ↑ Descendants

Tumor Necrosis Factors
View node CD30 Ligand
View node B-Cell Activating Factor
  C1QTNF3 protein, human
View node Antigens, CD70
View node CD40 Ligand
View node Fas Ligand Protein
View node Ectodysplasins
  Lymphotoxin alpha1, beta2 Heterotrimer
  M-sec protein, mouse
  TNFSF12 protein, human
  Tnfsf12 protein, mouse
  TNFSF18 protein, human
  Tnfsf18 protein, mouse
  Tnfsf4 protein, mouse
  Tnfsf4 protein, rat
View node Lymphotoxin-alpha
View node Tumor Necrosis Factor-alpha
View node Lymphotoxin-beta
View node OX40 Ligand
View node 4-1BB Ligand
View node TNF-Related Apoptosis-Inducing Ligand
View node RANK Ligand
View node Tumor Necrosis Factor Ligand Superfamily Member 13
View node Tumor Necrosis Factor Ligand Superfamily Member 14
View node Tumor Necrosis Factor Ligand Superfamily Member 15
  TWEAK protein, rat
  TWEAK protein, zebrafish