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Chemical B7-2 Antigen

Name B7-2 Antigen
Equivalent Terms Antigen, B7 2 | Antigen, B7-2 | Antigen, CD86 | Antigens, CD86 | B70 Costimulatory Molecule | B7 2 Antigen | B7-2 Costimulatory Molecule | CD86 Antigen | CD86 Antigens | Costimulatory Molecule, B70 | Costimulatory Molecule, B7-2 | Early T Cell Costimulatory Molecule 1
Definition A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
Curation Status No associations have been curated for this chemical yet.
MeSH® ID D051940
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Top ↑ Ancestors

1. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Antigens Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Antigens, Surface Has associated diseases Has associated phenotype references B7 Antigens B7-2 Antigen
2. ChemicalsBiological Factors Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Intercellular Signaling Peptides and Proteins Has associated genes Has associated diseases Has associated phenotype references B7 Antigens B7-2 Antigen

Top ↑ Descendants

B7-2 Antigen
  CD86 protein, human
  Cd86 protein, mouse
  Cd86 protein, rat